Literature DB >> 1968038

Probe, VK5B, is located in the same interval as the autosomal dominant adult polycystic kidney disease locus, PKD1.

V J Hyland1, G K Suthers, K Friend, R N MacKinnon, D F Callen, M H Breuning, T Keith, V A Brown, P Phipps, G R Sutherland.   

Abstract

The polymorphic DNA probe VK5B (D16S94) was mapped by genetic linkage in families from the Centre d'Etude de Polymorphisme Humain (CEPH) as being in the same interval as the autosomal dominant adult polycystic kidney disease locus (PKD1). The maximum likelihood estimate of the genetic location of VK5B using multipoint linkage analysis was 9.6 cM proximal to 3'HVR (D16S85) and 5.4 cM distal to CRI-0327 (D16S63), in males. The VK5B probe may be useful in PKD1 families for prenatal and presymptomatic diagnosis of the disease. Additional typing of PKD1 families is required to determine whether the location of VK5B is distal or proximal to (PKD1).

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Year:  1990        PMID： 1968038     DOI： 10.1007/bf00200577

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  11 in total

1.  Assignment of anonymous DNA probes to specific intervals of human chromosomes 16 and X.

Authors:  V J Hyland; K E Fernandez; D F Callen; R N MacKinnon; E Baker; K Friend; G R Sutherland
Journal:  Hum Genet       Date:  1989-08       Impact factor: 4.132

2.  Mapping the short arm of human chromosome 16.

Authors:  D F Callen; V J Hyland; E G Baker; A Fratini; A K Gedeon; J C Mulley; K E Fernandez; M H Breuning; G R Sutherland
Journal:  Genomics       Date:  1989-04       Impact factor: 5.736

Review 3.  Report of the committee on the genetic constitution of chromosome 16.

Authors:  S T Reeders; C E Hildebrand
Journal:  Cytogenet Cell Genet       Date:  1989

4.  Anonymous DNA probes to human chromosome 16 derived from a flow-purified library.

Authors:  V J Hyland; S Grist; D F Callen; G R Sutherland
Journal:  Am J Hum Genet       Date:  1988-02       Impact factor: 11.025

5.  Regional localization of the autosomal dominant polycystic kidney disease locus.

Authors:  S T Reeders; T Keith; P Green; G G Germino; N J Barton; O J Lehmann; V A Brown; P Phipps; J Morgan; J C Bear
Journal:  Genomics       Date:  1988-08       Impact factor: 5.736

6.  Two genetic markers closely linked to adult polycystic kidney disease on chromosome 16.

Authors:  S T Reeders; M H Breuning; G Corney; S J Jeremiah; P Meera Khan; K E Davies; D A Hopkinson; P L Pearson; D J Weatherall
Journal:  Br Med J (Clin Res Ed)       Date:  1986-03-29

7.  Linkage heterogeneity of autosomal dominant polycystic kidney disease.

Authors:  W J Kimberling; P R Fain; J B Kenyon; D Goldgar; E Sujansky; P A Gabow
Journal:  N Engl J Med       Date:  1988-10-06       Impact factor: 91.245

8.  Strategies for multilocus linkage analysis in humans.

Authors:  G M Lathrop; J M Lalouel; C Julier; J Ott
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

9.  Improved early diagnosis of adult polycystic kidney disease with flanking DNA markers.

Authors:  M H Breuning; S T Reeders; H Brunner; J W Ijdo; J J Saris; A Verwest; G J van Ommen; P L Pearson
Journal:  Lancet       Date:  1987-12-12       Impact factor: 79.321

10.  A second genetic locus for autosomal dominant polycystic kidney disease.

Authors:  G Romeo; M Devoto; G Costa; L Roncuzzi; L Catizone; P Zucchelli; G G Germino; T Keith; D J Weatherall; S T Reeders
Journal:  Lancet       Date:  1988-07-02       Impact factor: 79.321
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  8 in total

1.  Construction of a map of chromosome 16 by using radiation hybrids.

Authors:  I Ceccherini; G Romeo; S Lawrence; M H Breuning; P C Harris; H Himmelbauer; A M Frischauf; G R Sutherland; G G Germino; S T Reeders
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-01       Impact factor: 11.205

2.  Map of 16 polymorphic loci on the short arm of chromosome 16 close to the polycystic kidney disease gene (PKD1).

Authors:  M H Breuning; F G Snijdewint; H Brunner; A Verwest; J W Ijdo; J J Saris; J G Dauwerse; L Blonden; T Keith; D F Callen
Journal:  J Med Genet       Date:  1990-10       Impact factor: 6.318

3.  Saturating the region of the polycystic kidney disease gene with NotI linking clones.

Authors:  H Himmelbauer; G G Germino; I Ceccherini; G Romeo; S T Reeders; A M Frischauf
Journal:  Am J Hum Genet       Date:  1991-02       Impact factor: 11.025

4.  Genetic heterogeneity of polycystic kidney disease in Bulgaria.

Authors:  N Bogdanova; B Dworniczak; D Dragova; V Todorov; D Dimitrakov; K Kalinov; J Hallmayer; J Horst; L Kalaydjieva
Journal:  Hum Genet       Date:  1995-06       Impact factor: 4.132

5.  Linkage disequilibrium in the region of the autosomal dominant polycystic kidney disease gene (PKD1).

Authors:  A Snarey; S Thomas; M C Schneider; S E Pound; N Barton; A F Wright; S Somlo; G G Germino; P C Harris; S T Reeders
Journal:  Am J Hum Genet       Date:  1994-08       Impact factor: 11.025

Review 6.  Prenatal diagnosis of autosomal dominant polycystic kidney disease (PKD1) presenting in utero and prognosis for very early onset disease.

Authors:  K D MacDermot; A K Saggar-Malik; D L Economides; S Jeffery
Journal:  J Med Genet       Date:  1998-01       Impact factor: 6.318

7.  Diagnosis of adult polycystic kidney disease by genetic markers and ultrasonographic imaging in a voluntary family register.

Authors:  R G Elles; K A Hodgkinson; N P Mallick; D J O'Donoghue; A P Read; S Rimmer; E A Watters; R Harris
Journal:  J Med Genet       Date:  1994-02       Impact factor: 6.318

8.  Multipoint mapping of adult onset polycystic kidney disease (PKD1) on chromosome 16.

Authors:  P M Pignatelli; S E Pound; A D Carothers; A M Macnicol; P L Allan; M L Watson; A F Wright
Journal:  J Med Genet       Date:  1992-09       Impact factor: 6.318
  8 in total

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