Literature DB >> 196594

The synthesis of tritium-labelled human corticotropin of high specific radioactivity.

D E Brundish, R Wade.   

Abstract

Human [[3,5-3H2]Tyr23]corticotropin-(1-39)-nonatriacontapeptide of specific radioactivity 25.2 Ci/mmol, identical with unlabelled human corticotropin by several criteria, was prepared via the fully protected di-iodotyrosine compound. The latter was synthesized by classical procedures.

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Year:  1977        PMID： 196594      PMCID： PMC1164883          DOI： 10.1042/bj1650169

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  9 in total

1.  Purification and some properties of prolidase of swine kidney.

Authors:  N C DAVIS; E L SMITH
Journal:  J Biol Chem       Date:  1957-01       Impact factor: 5.157

2.  Adrenocorticotropin. 51. Synthesis and properties of analogues of the human hormone with tyrosine residues replaced by 3,5-diiodotyrosine.

Authors:  S Lemaire; D Yamashiro; C Behrens; C Hao Li
Journal:  J Am Chem Soc       Date:  1977-03-02       Impact factor: 15.419

3.  Tritiated peptides. Part 2. Synthesis of two [3,5-3H2-Tyr2]-analogues of corticotrophin.

Authors:  D E Brundish; J R Martin; R Wade
Journal:  J Chem Soc Perkin 1       Date:  1976

4.  On the metabolism of two adrenocorticotrophin analogues.

Authors:  J R Baker; H P Bennett; A M Hudson; C McMartin; G E Purdon
Journal:  Clin Endocrinol (Oxf)       Date:  1976       Impact factor: 3.478

5.  Properties of a simplified bioassay for adrenocorticotrophic activity using the steroidogenic response of isolated adrenal cells.

Authors:  P J Lowry; C McMartin; J Peters
Journal:  J Endocrinol       Date:  1973-10       Impact factor: 4.286

6.  [Synthesis of the human adrenal cortex hormone ( h ACTH) with a revised amino acid sequence].

Authors:  P Sieber; W Rittel; B Riniker
Journal:  Helv Chim Acta       Date:  1972       Impact factor: 2.164

7.  Complete amino acid analysis of peptides and proteins after hydrolysis by a mixture of sepharose-bound peptidases.

Authors:  H P Bennett; D F Elliott; B E Evans; P J Lowry; C McMartin
Journal:  Biochem J       Date:  1972-09       Impact factor: 3.857

8.  Fate of corticotrophins in an isolated adrenal-cell bioassay and decrease of peptide breakdown by cell purification.

Authors:  H P Bennett; G Bullock; P J Lowry; C McMartin; J Peters
Journal:  Biochem J       Date:  1974-02       Impact factor: 3.857

9.  Norephedrines as metabolites of ( 14 C)amphetamine in urine in man.

Authors:  J Caldwell; L G Dring; R T Williams
Journal:  Biochem J       Date:  1972-08       Impact factor: 3.857
  9 in total
  1 in total

1.  A rapid method, using octadecasilyl-silica, for the extraction of certain peptides from tissues.

Authors:  H P Bennett; A M Hudson; L Kelly; C McMartin; G E Purdon
Journal:  Biochem J       Date:  1978-12-01       Impact factor: 3.857
  1 in total

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