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Literature DB >> 19656481

The impact of air pollutants as an adjuvant for allergic sensitization and asthma.

Loida Viera¹, Karin Chen, Andre Nel, Maria Garcia Lloret.

Abstract

The current global epidemic of atopy and asthma has been related to the changes in environmental exposures brought about by the development and expansion of industrialized societies. This article reviews the evidence supporting the fundamental role of air pollutants in fostering allergic inflammation of the airways, with emphasis on the molecular and genetic pathways that link ambient particulate matter (PM) exposure to the induction of proinflammatory changes and proallergic effects in the respiratory tract. We propose that the link between PM exposure and proallergic effects involves organic PM components that generate oxygen radicals capable of perturbing the redox equilibrium mucosal immune cells.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2009 PMID： 19656481 DOI： 10.1007/s11882-009-0046-x

Source DB: PubMed Journal: Curr Allergy Asthma Rep ISSN： 1529-7322 Impact factor: 4.806

66 in total

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7 in total

Review 1. Perinatal and early childhood environmental factors influencing allergic asthma immunopathogenesis.

Authors: Jonathan M Gaffin; Watcharoot Kanchongkittiphon; Wanda Phipatanakul
Journal: Int Immunopharmacol Date: 2014-06-19 Impact factor: 4.932

2. Effects of distance from a heavily transited avenue on asthma and atopy in a periurban shantytown in Lima, Peru.

Authors: Lauren M Baumann; Colin L Robinson; Juan M Combe; Alfonso Gomez; Karina Romero; Robert H Gilman; Lilia Cabrera; Nadia N Hansel; Robert A Wise; Patrick N Breysse; Kathleen Barnes; Juan E Hernandez; William Checkley
Journal: J Allergy Clin Immunol Date: 2011-01-14 Impact factor: 10.793

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Authors: Jiyoun Kim; Sudha Natarajan; Louis J Vaickus; Jacqueline C Bouchard; Dominic Beal; William W Cruikshank; Daniel G Remick
Journal: Am J Pathol Date: 2011-10-01 Impact factor: 4.307

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Authors: Deborah Traversi; Piero Cervella; Giorgio Gilli
Journal: Environ Sci Pollut Res Int Date: 2014-08-21 Impact factor: 4.223