Literature DB >> 1964159

Expression of transforming growth factor-beta 3 by embryonal carcinoma cells, parietal endoderm-like cells and early mouse embryos.

W J Campbell1, D Kelly, A Rizzino.   

Abstract

Utilizing the technique of reverse transcription-polymerase chain reaction (RT-PCR), we have examined the expression of transforming growth factor-beta 3 (TGF-beta 3) by embryonal carcinoma (EC) cells, EC-derived differentiated cells and early mammalian embryos. Using a TGF-beta bioassay, we determined that PYS-2 cells express considerable TGF-beta activity that cannot be completely neutralized by antibodies specific for TGF-beta 1 and TGF-beta 2. We also have determined that PYS-2 cells, as well as F9 EC cells and their differentiated cells, express transcripts for TGF-beta 3. In addition, we have determined that blastocysts, cultured for three days in serum-containing medium, express TGF-beta 3 transcripts. Thus, our data suggest that expression of TGF-beta 3 is initiated during early stages of mammalian development.

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Year:  1990        PMID： 1964159     DOI： 10.1007/bf02623696

Source DB:  PubMed          Journal:  In Vitro Cell Dev Biol        ISSN： 0883-8364


  15 in total

1.  Production of PDGF-like growth factors by embryonal carcinoma cells and binding of PDGF to their endoderm-like differentiated cells.

Authors:  A Rizzino; D F Bowen-Pope
Journal:  Dev Biol       Date:  1985-07       Impact factor: 3.582

2.  The murine transforming growth factor-beta precursor.

Authors:  R Derynck; J A Jarrett; E Y Chen; D V Goeddel
Journal:  J Biol Chem       Date:  1986-04-05       Impact factor: 5.157

3.  Identification of another member of the transforming growth factor type beta gene family.

Authors:  P ten Dijke; P Hansen; K K Iwata; C Pieler; J G Foulkes
Journal:  Proc Natl Acad Sci U S A       Date:  1988-07       Impact factor: 11.205

4.  Early mouse embryos produce and release factors with transforming growth factor activity.

Authors:  A Rizzino
Journal:  In Vitro Cell Dev Biol       Date:  1985-09

Review 5.  Transforming growth factor-beta: multiple effects on cell differentiation and extracellular matrices.

Authors:  A Rizzino
Journal:  Dev Biol       Date:  1988-12       Impact factor: 3.582

6.  Appearance of high affinity receptors for type beta transforming growth factor during differentiation of murine embryonal carcinoma cells.

Authors:  A Rizzino
Journal:  Cancer Res       Date:  1987-08-15       Impact factor: 12.701

7.  Expression of transforming growth factor beta 2 during the differentiation of murine embryonal carcinoma and embryonic stem cells.

Authors:  C L Mummery; H Slager; W Kruijer; A Feijen; E Freund; I Koornneef; A J van den Eijnden-van Raaij
Journal:  Dev Biol       Date:  1990-01       Impact factor: 3.582

8.  Developmental expression of PDGF, TGF-alpha, and TGF-beta genes in preimplantation mouse embryos.

Authors:  D A Rappolee; C A Brenner; R Schultz; D Mark; Z Werb
Journal:  Science       Date:  1988-09-30       Impact factor: 47.728

9.  Human transforming growth factor-beta 3: recombinant expression, purification, and biological activities in comparison with transforming growth factors-beta 1 and -beta 2.

Authors:  J L Graycar; D A Miller; B A Arrick; R M Lyons; H L Moses; R Derynck
Journal:  Mol Endocrinol       Date:  1989-12

10.  Regulation and expression of transforming growth factor type-beta during early mammalian development.

Authors:  D Kelly; W J Campbell; J Tiesman; A Rizzino
Journal:  Cytotechnology       Date:  1990-11       Impact factor: 2.058
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  3 in total

1.  Expression of fibroblast growth factor receptors by embryonal carcinoma cells and early mouse embryos.

Authors:  W J Campbell; K A Miller; T M Anderson; J D Shull; A Rizzino
Journal:  In Vitro Cell Dev Biol       Date:  1992-01

2.  Transcriptional regulation of the TGF-beta 2 gene in choriocarcinoma cells and breast carcinoma cells: differential utilization of Cis-regulatory elements.

Authors:  M Kingsley-Kallesen; L Johnson; B Scholtz; D Kelly; A Rizzino
Journal:  In Vitro Cell Dev Biol Anim       Date:  1997-04       Impact factor: 2.723

3.  Co-expression analysis of fetal weight-related genes in ovine skeletal muscle during mid and late fetal development stages.

Authors:  Lingyang Xu; Fuping Zhao; Hangxing Ren; Li Li; Jian Lu; Jiasen Liu; Shifang Zhang; George E Liu; Jiuzhou Song; Li Zhang; Caihong Wei; Lixin Du
Journal:  Int J Biol Sci       Date:  2014-09-11       Impact factor: 6.580
  3 in total

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