Literature DB >> 19629222

Current diagnosis and treatment of spondylodiscitis.

Rolf Sobottke1, Harald Seifert, Gerd Fätkenheuer, Matthias Schmidt, Axel Gossmann, Peer Eysel.   

Abstract

INTRODUCTION: Infection of the spinal column is rare, and often recognized and treated too late. Spondylodiscitis is osteomyelitis of the spine and can cause severe symptoms. Hospital mortality is in the region of 2% to 17%.
METHODS: Selective literature review and results of the authors' own research.
RESULTS: The incidence of pyogenic spondylodiscitis is around 1 : 250 000, which represents around 3% to 5% of osteomyelitis as a whole. 10% to 15% of all vertebral infections can be ascribed to exogenous spondylodiscitis, with Staphylococcus aureus as the commonest pathogen, 2% to 16% of which are reported to be MRSA (methicillin-resistant S. aureus). Catheter-related, nosocomial infection with MRSA is a key cause for spondylodiscitis. 50% of all skeletal tuberculoses are found in the spine. DISCUSSION: Spondylodiscitis should be borne in mind in cases of diffuse back pain and non-specific symptoms. MRI is the diagnostic modality of choice for detecting spondylodiscitis. Thanks to precise monitoring of conservative treatments and primarily stable surgical techniques, prolonged immobilization of the patient is no longer necessary nowadays.

Entities:  

Keywords:  spinal infection; spine; spondylitis; spondylodiscitis; vertebral osteomyelitis

Year:  2008        PMID: 19629222      PMCID: PMC2696793          DOI: 10.3238/arztebl.2008.0181

Source DB:  PubMed          Journal:  Dtsch Arztebl Int        ISSN: 1866-0452            Impact factor:   5.594


  28 in total

1.  Primary stable anterior instrumentation or dorsoventral spondylodesis in spondylodiscitis? Results of a comparative study.

Authors:  P Eysel; C Hopf; I Vogel; J D Rompe
Journal:  Eur Spine J       Date:  1997       Impact factor: 3.134

Review 2.  Fungal infections of the spine.

Authors:  Choll W Kim; Andrew Perry; Brad Currier; Michael Yaszemski; Steven R Garfin
Journal:  Clin Orthop Relat Res       Date:  2006-03       Impact factor: 4.176

3.  Fluorine-18 fluorodeoxyglucose positron emission tomography findings in spondylodiscitis: preliminary results.

Authors:  A Schmitz; J H Risse; F Grünwald; F Gassel; H J Biersack; O Schmitt
Journal:  Eur Spine J       Date:  2001-12       Impact factor: 3.134

4.  [Infectious spondylitis. A retrospective evaluation of MRI markers].

Authors:  M Wikström; J Vogel; N Rilinger; M Diepers; E Hartwig; A Rieber
Journal:  Radiologe       Date:  1997-02       Impact factor: 0.635

5.  Pyogenic spinal infections and outcome according to the 36-item short form health survey.

Authors:  Chris Woertgen; Ralf Dirk Rothoerl; Carsten Englert; Carsten Neumann
Journal:  J Neurosurg Spine       Date:  2006-06

Review 6.  [Chronic infections of the skeletal system. Their imaging diagnosis].

Authors:  C Glaser; M Matzko; M Reiser
Journal:  Radiologe       Date:  2000-06       Impact factor: 0.635

Review 7.  Suggestions for managing pyogenic (non-tuberculous) discitis in adults.

Authors:  Franck Grados; François Xavier Lescure; Eric Senneville; René Marc Flipo; Jean Luc Schmit; Patrice Fardellone
Journal:  Joint Bone Spine       Date:  2007-02-02       Impact factor: 4.929

8.  Discitis following removal of intervertebral disc.

Authors:  T S Lindholm; P Pylkkänen
Journal:  Spine (Phila Pa 1976)       Date:  1982 Nov-Dec       Impact factor: 3.468

9.  Vertebral osteomyelitis: assessment using MR.

Authors:  M T Modic; D H Feiglin; D W Piraino; F Boumphrey; M A Weinstein; P M Duchesneau; S Rehm
Journal:  Radiology       Date:  1985-10       Impact factor: 11.105

10.  Surgical treatment of spondylodiscitis.

Authors:  Christian Schinkel; Matthias Gottwald; Hans-Joachim Andress
Journal:  Surg Infect (Larchmt)       Date:  2003       Impact factor: 2.150

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  63 in total

Review 1.  [Quality indicators for managing patients with low back pain].

Authors:  J F Chenot
Journal:  Schmerz       Date:  2010-06       Impact factor: 1.107

Review 2.  Treatment of spondylodiscitis.

Authors:  Kourosh Zarghooni; Marc Röllinghoff; Rolf Sobottke; Peer Eysel
Journal:  Int Orthop       Date:  2011-12-06       Impact factor: 3.075

3.  Surgical management of pyogenic discitis of lumbar region.

Authors:  Pramod Devkota; R Krishnakumar; J Renjith Kumar
Journal:  Asian Spine J       Date:  2014-04-08

Review 4.  Pediatric spinal infections-a review of non-tuberculous infections.

Authors:  Chandan B Mohanty; Graham Fieggen; Chandrashekhar E Deopujari
Journal:  Childs Nerv Syst       Date:  2018-07-03       Impact factor: 1.475

5.  Specific spinal pathologies in adult patients with an acute or subacute atraumatic low back pain in the emergency department.

Authors:  Aleksi Reito; Kati Kyrölä; Liisa Pekkanen; Juha Paloneva
Journal:  Int Orthop       Date:  2018-05-29       Impact factor: 3.075

6.  [Standards of microbiological diagnostics of spondylodiscitis].

Authors:  B Lehner; M Akbar; C Rehnitz; G W Omlor; U Dapunt; I Burckhardt
Journal:  Orthopade       Date:  2012-09       Impact factor: 1.087

7.  [Systemic and local antibiotic therapy of conservative and operative treatment of spondylodiscitis].

Authors:  C Fleege; T A Wichelhaus; M Rauschmann
Journal:  Orthopade       Date:  2012-09       Impact factor: 1.087

8.  Robot guidance for percutaneous minimally invasive placement of pedicle screws for pyogenic spondylodiscitis is associated with lower rates of wound breakdown compared to conventional fluoroscopy-guided instrumentation.

Authors:  Awad Alaid; Kajetan von Eckardstein; Nicolas Roydon Smoll; Volodymyr Solomiichuk; Veit Rohde; Ramon Martinez; Bawarjan Schatlo
Journal:  Neurosurg Rev       Date:  2017-07-20       Impact factor: 3.042

Review 9.  The orthotic treatment of acute and chronic disease of the cervical and lumbar spine.

Authors:  Kourosh Zarghooni; Frank Beyer; Jan Siewe; Peer Eysel
Journal:  Dtsch Arztebl Int       Date:  2013-11-01       Impact factor: 5.594

10.  [Operative therapy of bacterial spondylodiscitis: a retrospective study].

Authors:  C Ewald; J Gartemann; S A Kuhn; J Walter; R Kalff
Journal:  Orthopade       Date:  2009-03       Impact factor: 1.087

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