Literature DB >> 19606868

Neglected tropical diseases: multi-target-directed ligands in the search for novel lead candidates against Trypanosoma and Leishmania.

Andrea Cavalli1, Maria Laura Bolognesi.   

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Year:  2009        PMID： 19606868     DOI： 10.1021/jm9004835

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  32 in total

Review 1.  Mitochondria and trypanosomatids: targets and drugs.

Authors:  Lianet Monzote Fidalgo; Lars Gille
Journal:  Pharm Res       Date:  2011-09-21       Impact factor: 4.200

2.  New organoruthenium complexes with bioactive thiosemicarbazones as co-ligands: potential anti-trypanosomal agents.

Authors:  Bruno Demoro; Cynthia Sarniguet; Roberto Sánchez-Delgado; Miriam Rossi; Daniel Liebowitz; Francesco Caruso; Claudio Olea-Azar; Virtudes Moreno; Andrea Medeiros; Marcelo A Comini; Lucía Otero; Dinorah Gambino
Journal:  Dalton Trans       Date:  2011-12-02       Impact factor: 4.390

Review 3.  Chemistry and biology of multicomponent reactions.

Authors:  Alexander Dömling; Wei Wang; Kan Wang
Journal:  Chem Rev       Date:  2012-03-22       Impact factor: 60.622

Review 4.  Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis.

Authors:  Advait S Nagle; Shilpi Khare; Arun Babu Kumar; Frantisek Supek; Andriy Buchynskyy; Casey J N Mathison; Naveen Kumar Chennamaneni; Nagendar Pendem; Frederick S Buckner; Michael H Gelb; Valentina Molteni
Journal:  Chem Rev       Date:  2014-11-03       Impact factor: 60.622

5.  Untargeted LC-MS metabolomic studies of Asteraceae species to discover inhibitors of Leishmania major dihydroorotate dehydrogenase.

Authors:  Lucas A Chibli; Annylory L Rosa; Maria Cristina Nonato; Fernando B Da Costa
Journal:  Metabolomics       Date:  2019-04-04       Impact factor: 4.290

6.  Almiramides A-C: discovery and development of a new class of leishmaniasis lead compounds.

Authors:  Laura M Sanchez; Dioxelis Lopez; Brian A Vesely; Gina Della Togna; William H Gerwick; Dennis E Kyle; Roger G Linington
Journal:  J Med Chem       Date:  2010-05-27       Impact factor: 7.446

Review 7.  Sterol 14alpha-demethylase (CYP51) as a therapeutic target for human trypanosomiasis and leishmaniasis.

Authors:  Galina I Lepesheva; Michael R Waterman
Journal:  Curr Top Med Chem       Date:  2011       Impact factor: 3.295

8.  Risedronate metal complexes potentially active against Chagas disease.

Authors:  Bruno Demoro; Francesco Caruso; Miriam Rossi; Diego Benítez; Mercedes Gonzalez; Hugo Cerecetto; Beatriz Parajón-Costa; Jorge Castiglioni; Melina Galizzi; Roberto Docampo; Lucía Otero; Dinorah Gambino
Journal:  J Inorg Biochem       Date:  2010-08-14       Impact factor: 4.155

9.  Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei.

Authors:  Laura M Sanchez; Giselle M Knudsen; Claudia Helbig; Geraldine De Muylder; Samantha M Mascuch; Zachary B Mackey; Lena Gerwick; Christine Clayton; James H McKerrow; Roger G Linington
Journal:  J Nat Prod       Date:  2013-02-27       Impact factor: 4.050

10.  Development of a New Antileishmanial Aziridine-2,3-Dicarboxylate-Based Inhibitor with High Selectivity for Parasite Cysteine Proteases.

Authors:  Caroline Schad; Ulrike Baum; Benjamin Frank; Uwe Dietzel; Felix Mattern; Carlos Gomes; Alicia Ponte-Sucre; Heidrun Moll; Uta Schurigt; Tanja Schirmeister
Journal:  Antimicrob Agents Chemother       Date:  2015-11-23       Impact factor: 5.191
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