Literature DB >> 25365529

Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis.

Advait S Nagle1, Shilpi Khare1, Arun Babu Kumar, Frantisek Supek1, Andriy Buchynskyy, Casey J N Mathison1, Naveen Kumar Chennamaneni, Nagendar Pendem, Frederick S Buckner, Michael H Gelb, Valentina Molteni1.   

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Year:  2014        PMID： 25365529      PMCID： PMC4633805          DOI： 10.1021/cr500365f

Source DB:  PubMed          Journal:  Chem Rev        ISSN： 0009-2665            Impact factor:   60.622


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  394 in total

Review 1.  Advances in leishmaniasis.

Authors:  Henry W Murray; Jonathan D Berman; Clive R Davies; Nancy G Saravia
Journal:  Lancet       Date:  2005 Oct 29-Nov 4       Impact factor: 79.321

Review 2.  Post-kala-azar dermal leishmaniasis.

Authors:  V Ramesh; A Mukherjee
Journal:  Int J Dermatol       Date:  1995-02       Impact factor: 2.736

3.  Inhibition of glycosylphosphatidylinositol biosynthesis in Leishmania mexicana by mannosamine.

Authors:  M C Field; E Medina-Acosta; G A Cross
Journal:  J Biol Chem       Date:  1993-05-05       Impact factor: 5.157

4.  Drug regimens for visceral leishmaniasis in Mediterranean countries.

Authors:  Luigi Gradoni; Ketty Soteriadou; Hecmi Louzir; Allal Dakkak; Seray Ozensoy Toz; Charles Jaffe; Jean-Pierre Dedet; Lenea Campino; Carmen Cañavate; Jean-Claude Dujardin
Journal:  Trop Med Int Health       Date:  2008-08-24       Impact factor: 2.622

5.  Azaterphenyl diamidines as antileishmanial agents.

Authors:  Laixing Hu; Reem K Arafa; Mohamed A Ismail; Tanja Wenzler; Reto Brun; Manoj Munde; W David Wilson; Sandra Nzimiro; Serene Samyesudhas; Karl A Werbovetz; David W Boykin
Journal:  Bioorg Med Chem Lett       Date:  2007-10-30       Impact factor: 2.823

6.  In vitro activity of Tridax procumbens against promastigotes of Leishmania mexicana.

Authors:  Zhelmy Martín-Quintal; Rosa Moo-Puc; Francisco González-Salazar; Manuel J Chan-Bacab; Luis W Torres-Tapia; Sergio R Peraza-Sánchez
Journal:  J Ethnopharmacol       Date:  2009-02-10       Impact factor: 4.360

7.  Synthesis, biological evaluation, and molecular modeling of 3,5-substituted-N1-phenyl-N4,N4-di-n-butylsulfanilamides as antikinetoplastid antimicrotubule agents.

Authors:  Tesmol G George; Molla M Endeshaw; Rachel E Morgan; Kiran V Mahasenan; Dawn A Delfín; Mitali S Mukherjee; Adam J Yakovich; Jean Fotie; Chenglong Li; Karl A Werbovetz
Journal:  Bioorg Med Chem       Date:  2007-06-27       Impact factor: 3.641

8.  Placebo-controlled clinical trial of sodium stibogluconate (Pentostam) versus ketoconazole for treating cutaneous leishmaniasis in Guatemala.

Authors:  T R Navin; B A Arana; F E Arana; J D Berman; J F Chajón
Journal:  J Infect Dis       Date:  1992-03       Impact factor: 5.226

9.  Risk for human African trypanosomiasis, Central Africa, 2000-2009.

Authors:  Pere P Simarro; Giuliano Cecchi; José R Franco; Massimo Paone; Eric M Fèvre; Abdoulaye Diarra; José Antonio Ruiz Postigo; Raffaele C Mattioli; Jean G Jannin
Journal:  Emerg Infect Dis       Date:  2011-12       Impact factor: 6.883

10.  One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screening.

Authors:  Chidochangu P Mpamhanga; Daniel Spinks; Lindsay B Tulloch; Emma J Shanks; David A Robinson; Iain T Collie; Alan H Fairlamb; Paul G Wyatt; Julie A Frearson; William N Hunter; Ian H Gilbert; Ruth Brenk
Journal:  J Med Chem       Date:  2009-07-23       Impact factor: 7.446
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  66 in total

1.  Discovery of N-(2-aminoethyl)-N-benzyloxyphenyl benzamides: New potent Trypanosoma brucei inhibitors.

Authors:  Andriy Buchynskyy; J Robert Gillespie; Matthew A Hulverson; Joshua McQueen; Sharon A Creason; Ranae M Ranade; Nicole A Duster; Michael H Gelb; Frederick S Buckner
Journal:  Bioorg Med Chem       Date:  2016-11-12       Impact factor: 3.641

2.  8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases.

Authors:  Cyril Fersing; Clotilde Boudot; Julien Pedron; Sébastien Hutter; Nicolas Primas; Caroline Castera-Ducros; Sandra Bourgeade-Delmas; Alix Sournia-Saquet; Alain Moreau; Anita Cohen; Jean-Luc Stigliani; Geneviève Pratviel; Maxime D Crozet; Susan Wyllie; Alan Fairlamb; Alexis Valentin; Pascal Rathelot; Nadine Azas; Bertrand Courtioux; Pierre Verhaeghe; Patrice Vanelle
Journal:  Eur J Med Chem       Date:  2018-08-01       Impact factor: 6.514

3.  Tetraazamacrocyclic derivatives and their metal complexes as antileishmanial leads.

Authors:  Timothy J Hubin; Ashlie N Walker; Dustin J Davilla; TaRynn N Carder Freeman; Brittany M Epley; Travis R Hasley; Prince N A Amoyaw; Surendra Jain; Stephen J Archibald; Timothy J Prior; Jeanette A Krause; Allen G Oliver; Babu L Tekwani; M Omar F Khan
Journal:  Polyhedron       Date:  2019-02-23       Impact factor: 3.052

4.  A new multi-epitope peptide vaccine induces immune responses and protection against Leishmania infantum in BALB/c mice.

Authors:  Bahareh Vakili; Navid Nezafat; Bijan Zare; Nasrollah Erfani; Maryam Akbari; Younes Ghasemi; Mohammad Reza Rahbar; Gholam Reza Hatam
Journal:  Med Microbiol Immunol       Date:  2019-11-06       Impact factor: 3.402

5.  Screening for Small Molecule Modulators of Trypanosoma brucei Hsp70 Chaperone Activity Based upon Alcyonarian Coral-Derived Natural Products.

Authors:  Sarah K Andreassend; Stephen J Bentley; Gregory L Blatch; Aileen Boshoff; Robert A Keyzers
Journal:  Mar Drugs       Date:  2020-01-27       Impact factor: 5.118

6.  Enterocin AS-48 as Evidence for the Use of Bacteriocins as New Leishmanicidal Agents.

Authors:  María Ángeles Abengózar; Rubén Cebrián; José María Saugar; Teresa Gárate; Eva Valdivia; Manuel Martínez-Bueno; Mercedes Maqueda; Luis Rivas
Journal:  Antimicrob Agents Chemother       Date:  2017-03-24       Impact factor: 5.191

7.  In Vitro and In Vivo Characterization of Potent Antileishmanial Methionine Aminopeptidase 1 Inhibitors.

Authors:  Felipe Rodriguez; Sarah F John; Eva Iniguez; Sebastian Montalvo; Karina Michael; Lyndsey White; Dong Liang; Omonike A Olaleye; Rosa A Maldonado
Journal:  Antimicrob Agents Chemother       Date:  2020-05-21       Impact factor: 5.191

8.  Discovery of a quinoline-based phenyl sulfone derivative as an antitrypanosomal agent.

Authors:  Huaisheng Zhang; Jasmine Collins; Rogers Nyamwihura; Shelbi Ware; Marcel Kaiser; Ifedayo Victor Ogungbe
Journal:  Bioorg Med Chem Lett       Date:  2018-03-24       Impact factor: 2.823

9.  Identification of non-peptidic cysteine reactive fragments as inhibitors of cysteine protease rhodesain.

Authors:  Danielle McShan; Stefan Kathman; Brittiney Lowe; Ziyang Xu; Jennifer Zhan; Alexander Statsyuk; Ifedayo Victor Ogungbe
Journal:  Bioorg Med Chem Lett       Date:  2015-09-02       Impact factor: 2.823

Review 10.  Novel lead compounds in pre-clinical development against African sleeping sickness.

Authors:  Michael Berninger; Ines Schmidt; Alicia Ponte-Sucre; Ulrike Holzgrabe
Journal:  Medchemcomm       Date:  2017-07-31       Impact factor: 3.597
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