Literature DB >> 19603582

Influence of chlorhexidine concentration on the durability of etch-and-rinse dentin bonds: a 12-month in vitro study.

Lorenzo Breschi1, Federica Cammelli, Erika Visintini, Annalisa Mazzoni, Francesca Vita, Marcela Carrilho, Milena Cadenaro, Stephen Foulger, Giovanni Mazzoti, Franklin R Tay, Roberto Di Lenarda, David Pashley.   

Abstract

PURPOSE: To investigate the effect of 0.2% and 2% chlorhexidine (CHX) used as a therapeutic primer on the long-term bond strengths of two etch-and-rinse adhesive systems.
MATERIALS AND METHODS: Adper Scotchbond 1XT (SB1) and XP-Bond (XPB) were evaluated. Etched dentin substrates were assigned to 6 treatment groups: (1) 0.2% CHX + SB1; (2) 2% CHX + SB1; (3) SB1 (control); (4) 0.2% CHX + XPB; (5) 2% CHX + XPB; (6) XPB (control). Composite buildups were made and beams prepared for microtensile bond strength testing. Beams were divided into 3 subgroups and either immediately pulled to failure or stored in artificial saliva for 6 or 12 months prior to testing. Data were evaluated with three-way ANOVA. Additional adhesive interfaces were prepared to investigate nanoleakage expression by TEM.
RESULTS: SB1 and XPB showed similar immediate bond strength values with or without CHX pretreatment (p > 0.05). After 12 months, bonds fell from 43.9 +/- 9.5 MPa to 20.1 +/- 5.4 MPa and from 39.6 +/- 9.4 MPa to 14.2 +/- 5.0 MPa in control specimens for SB1 and XPB respectively, while bond fell only from 41.9 +/- 9.6MPa to 33.2 +/- 8.3 MPa and 38.3 +/- 8.9 MPa to 26.5 +/- 10.9 (for SB1 and XPB, respectively) when 0.2% CHX was previously used. CHX concentration did not affect bond strength values (0.2% vs 2%, p > 0.05). Nanoleakage increased during aging in controls, but reduced silver deposits were found in CHX-treated specimens.
CONCLUSION: Chlorhexidine significantly reduced the loss of bond strength seen in control bonds. Since no bacterial growth was present in the aging conditions, the results of this study suggest that endogenous factors thought to degrade the adhesive interface can be inhibited by CHX. Further in vivo trials should confirm the role of CHX in bond durability.

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Year:  2009        PMID: 19603582      PMCID: PMC3817484     

Source DB:  PubMed          Journal:  J Adhes Dent        ISSN: 1461-5185            Impact factor:   2.359


  48 in total

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2.  The effect of caries detector dyes and a cavity cleansing agent on composite resin bonding to enamel and dentin.

Authors:  A A el-Housseiny; H Jamjoum
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Review 3.  Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry.

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Journal:  Circ Res       Date:  2003-05-02       Impact factor: 17.367

4.  Single-step adhesives are permeable membranes.

Authors:  Franklin R Tay; David H Pashley; Byoung I Suh; Ricardo M Carvalho; Anut Itthagarun
Journal:  J Dent       Date:  2002 Sep-Nov       Impact factor: 4.379

Review 5.  Failure, repair, refurbishing and longevity of restorations.

Authors:  I A Mjör; V V Gordan
Journal:  Oper Dent       Date:  2002 Sep-Oct       Impact factor: 2.440

6.  Micromorphological changes in resin-dentin bonds after 1 year of water storage.

Authors:  Masanori Hashimoto; Hiroki Ohno; Hidehiko Sano; Franklin R Tay; Masayuki Kaga; Yoshiyuki Kudou; Haruhisa Oguchi; Yoshima Araki; Minoru Kubota
Journal:  J Biomed Mater Res       Date:  2002

7.  Interactions between resin monomers and commercial composite resins with human saliva derived esterases.

Authors:  F Jaffer; Y Finer; J P Santerre
Journal:  Biomaterials       Date:  2002-04       Impact factor: 12.479

8.  Two modes of nanoleakage expression in single-step adhesives.

Authors:  F R Tay; D H Pashley; M Yoshiyama
Journal:  J Dent Res       Date:  2002-07       Impact factor: 6.116

9.  The localization of matrix metalloproteinase-20 (MMP-20, enamelysin) in mature human teeth.

Authors:  M Sulkala; M Larmas; T Sorsa; T Salo; L Tjäderhane
Journal:  J Dent Res       Date:  2002-09       Impact factor: 6.116

10.  Water treeing--a potential mechanism for degradation of dentin adhesives.

Authors:  Franklin R Tay; David H Pashley
Journal:  Am J Dent       Date:  2003-02       Impact factor: 1.522

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  35 in total

Review 1.  Mechanisms regulating the degradation of dentin matrices by endogenous dentin proteases and their role in dental adhesion. A review.

Authors:  Camila Sabatini; David H Pashley
Journal:  Am J Dent       Date:  2014-08       Impact factor: 1.522

Review 2.  Strategies to prevent hydrolytic degradation of the hybrid layer-A review.

Authors:  Leo Tjäderhane; Fabio D Nascimento; Lorenzo Breschi; Annalisa Mazzoni; Ivarne L S Tersariol; Saulo Geraldeli; Arzu Tezvergil-Mutluay; Marcela Carrilho; Ricardo M Carvalho; Franklin R Tay; David H Pashley
Journal:  Dent Mater       Date:  2013-08-14       Impact factor: 5.304

3.  Substantivity of chlorhexidine to human dentin.

Authors:  Marcela R Carrilho; Ricardo M Carvalho; Ethan N Sousa; José Nicolau; Lorenzo Breschi; Annalisa Mazzoni; Leo Tjäderhane; Franklin R Tay; Kelli Agee; David H Pashley
Journal:  Dent Mater       Date:  2010-05-15       Impact factor: 5.304

4.  Use of a specific MMP-inhibitor (galardin) for preservation of hybrid layer.

Authors:  Lorenzo Breschi; Patrizia Martin; Annalisa Mazzoni; Fernando Nato; Marcela Carrilho; Leo Tjäderhane; Erika Visintini; Milena Cadenaro; Franklin R Tay; Elettra De Stefano Dorigo; David H Pashley
Journal:  Dent Mater       Date:  2010-03-17       Impact factor: 5.304

5.  Effect of epigallocatechin-3-gallate and thermal cycling on the bond strength of resin cements to the root dentin.

Authors:  Danielle Cristine Messias; Moisés Franco Barbosa da Silva; Natália Spadini de Faria; Tatiane Rocco Dias-Arnez; Fuad Jacob Rached-Júnior; Ana Beatriz Silva Sousa
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Review 6.  State of the art etch-and-rinse adhesives.

Authors:  David H Pashley; Franklin R Tay; Lorenzo Breschi; Leo Tjäderhane; Ricardo M Carvalho; Marcela Carrilho; Arzu Tezvergil-Mutluay
Journal:  Dent Mater       Date:  2010-11-27       Impact factor: 5.304

7.  Zinc reduces collagen degradation in demineralized human dentin explants.

Authors:  R Osorio; M Yamauti; E Osorio; M E Ruiz-Requena; D H Pashley; F R Tay; M Toledano
Journal:  J Dent       Date:  2010-11-23       Impact factor: 4.379

8.  Can 1% chlorhexidine diacetate and ethanol stabilize resin-dentin bonds?

Authors:  Adriana Pigozzo Manso; Rosa Helena Miranda Grande; Ana Karina Bedran-Russo; Alessandra Reis; Alessandro D Loguercio; David Henry Pashley; Ricardo Marins Carvalho
Journal:  Dent Mater       Date:  2014-05-09       Impact factor: 5.304

Review 9.  MMP Inhibitors on Dentin Stability: A Systematic Review and Meta-analysis.

Authors:  A F Montagner; R Sarkis-Onofre; T Pereira-Cenci; M S Cenci
Journal:  J Dent Res       Date:  2014-06-16       Impact factor: 6.116

10.  Chlorhexidine stabilizes the adhesive interface: a 2-year in vitro study.

Authors:  Lorenzo Breschi; Annalisa Mazzoni; Fernando Nato; Marcela Carrilho; Erika Visintini; Leo Tjäderhane; Alessandra Ruggeri; Franklin R Tay; Elettra De Stefano Dorigo; David H Pashley
Journal:  Dent Mater       Date:  2009-12-31       Impact factor: 5.304

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