Literature DB >> 19590625

Outcomes in pancreatic resection are negatively influenced by pre-operative hospitalization.

Wande B Pratt1, Charles M Vollmer, Mark P Callery.   

Abstract

BACKGROUND: Quality improvement in high-acuity surgery increasingly relies on clinical pathways to streamline patient care and to maximize cost-efficiency. Yet, it remains unclear whether immediate pre-operative hospitalization (non-elective resection) influences operative performance and to what extent it alters the post-operative course.
METHODS: Retrospective case series, cost analysis.University tertiary care referral centre. Four hundred and twelve consecutive pancreatic resections performed for benign and malignant disease between 2001 and 2008. Outcomes for both elective and non-elective operations were scrutinized, and correlated with deviations from our clinical Carepath for Pancreatic Resection. Observed-to-expected (O/E) morbidity ratios were calculated for each.
RESULTS: Overall, 39 patients (10%) required immediate pre-operative hospitalization, 22 (56%) of which were transferred from another hospital. The most common indications were pancreatitis, gastric outlet obstruction, intractable abdominal pain and gastrointestinal bleeding. During a 1- to 2-week hospitalization, 51% of patients underwent endoscopic retrograde cholangio-pancreatography (ERCP), 36% were administered parenteral nutrition, 20% received antibiotics and 15% were transfused blood products. Yet, this pre-operative scenario, at a median cost of $7250 per patient, had no measurable impact on operative performance. Post-operatively, non-elective patients suffered more complications and a higher (O/E) ratio (1.00 vs. 0.93). These outcomes resulted in significantly more deviations from our carepath and an additional $7000 per non-elective case.
CONCLUSION: Immediate pre-operative hospitalization has no meaningful impact on operative performance; yet, deviations from a standardized clinical pathway are far more likely after non-elective pancreatic resection, and result in more severe clinical and economic outcomes.

Entities:  

Keywords:  clinical pathway; complications; costs; pancreatic cancer; pancreatic resection; pancreaticoduodenectomy; quality; surgical outcomes

Year:  2009        PMID: 19590625      PMCID: PMC2697868          DOI: 10.1111/j.1477-2574.2008.00012.x

Source DB:  PubMed          Journal:  HPB (Oxford)        ISSN: 1365-182X            Impact factor:   3.647


  23 in total

1.  Hospital volume and surgical mortality in the United States.

Authors:  John D Birkmeyer; Andrea E Siewers; Emily V A Finlayson; Therese A Stukel; F Lee Lucas; Ida Batista; H Gilbert Welch; David E Wennberg
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2.  Critical pathway effectiveness: assessing the impact of patient, hospital care, and pathway characteristics using qualitative comparative analysis.

Authors:  Sydney M Dy; Pushkal Garg; Dorothy Nyberg; Patricia B Dawson; Peter J Pronovost; Laura Morlock; Haya Rubin; Albert W Wu
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3.  One thousand consecutive pancreaticoduodenectomies.

Authors:  John L Cameron; Taylor S Riall; JoAnn Coleman; Kenneth A Belcher
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4.  Deviation-based cost modeling: a novel model to evaluate the clinical and economic impact of clinical pathways.

Authors:  Tsafrir Vanounou; Wande Pratt; Josef E Fischer; Charles M Vollmer; Mark P Callery
Journal:  J Am Coll Surg       Date:  2007-04       Impact factor: 6.113

5.  Quality assessment in high-acuity surgery: volume and mortality are not enough.

Authors:  Charles M Vollmer; Wande Pratt; Tsafrir Vanounou; Shishir K Maithel; Mark P Callery
Journal:  Arch Surg       Date:  2007-04

6.  Cost and utilization impact of a clinical pathway for patients undergoing pancreaticoduodenectomy.

Authors:  G A Porter; P W Pisters; C Mansyur; A Bisanz; K Reyna; P Stanford; J E Lee; D B Evans
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7.  Assessment of complications after pancreatic surgery: A novel grading system applied to 633 patients undergoing pancreaticoduodenectomy.

Authors:  Michelle L DeOliveira; Jordan M Winter; Markus Schafer; Steven C Cunningham; John L Cameron; Charles J Yeo; Pierre-Alain Clavien
Journal:  Ann Surg       Date:  2006-12       Impact factor: 12.969

8.  Hospital volume and late survival after cancer surgery.

Authors:  John D Birkmeyer; Yating Sun; Sandra L Wong; Therese A Stukel
Journal:  Ann Surg       Date:  2007-05       Impact factor: 12.969

9.  Impact of hospital volume on operative mortality for major cancer surgery.

Authors:  C B Begg; L D Cramer; W J Hoskins; M F Brennan
Journal:  JAMA       Date:  1998-11-25       Impact factor: 56.272

10.  Critical pathways as a strategy for improving care: problems and potential.

Authors:  S D Pearson; D Goulart-Fisher; T H Lee
Journal:  Ann Intern Med       Date:  1995-12-15       Impact factor: 25.391

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  4 in total

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Authors:  Lidewij Spelt; Daniel Ansari; Christian Sturesson; Bobby Tingstedt; Roland Andersson
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Review 2.  Systematic review and meta-analysis of enhanced recovery after pancreatic surgery with particular emphasis on pancreaticoduodenectomies.

Authors:  M M E Coolsen; R M van Dam; A A van der Wilt; K Slim; K Lassen; C H C Dejong
Journal:  World J Surg       Date:  2013-08       Impact factor: 3.352

3.  Modified Frailty Index Predicts Morbidity and Mortality After Pancreaticoduodenectomy.

Authors:  Harveshp Mogal; Sarah A Vermilion; Rebecca Dodson; Fang-Chi Hsu; Russell Howerton; Perry Shen; Clancy J Clark
Journal:  Ann Surg Oncol       Date:  2017-01-05       Impact factor: 5.344

4.  The impact of recent hospitalization on surgical site infection after a pancreatectomy.

Authors:  Dominic E Sanford; Steven M Strasberg; William G Hawkins; Ryan C Fields
Journal:  HPB (Oxford)       Date:  2015-07-29       Impact factor: 3.647

  4 in total

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