| Literature DB >> 19588452 |
Abstract
Harrell's c-index or concordance C has been widely used as a measure of separation of two survival distributions. In the absence of censored data, the c-index estimates the Mann-Whitney parameter Pr(X>Y), which has been repeatedly utilized in various statistical contexts. In the presence of randomly censored data, the c-index no longer estimates Pr(X>Y); rather, a parameter that involves the underlying censoring distributions. This is in contrast to Efron's maximum likelihood estimator of the Mann-Whitney parameter, which is recommended in the setting of random censorship.Mesh:
Year: 2009 PMID: 19588452 DOI: 10.1002/bimj.200800228
Source DB: PubMed Journal: Biom J ISSN: 0323-3847 Impact factor: 2.207