Literature DB >> 19587925

A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides.

Michelle T Ma1, John A Karas, Jonathan M White, Denis Scanlon, Paul S Donnelly.   

Abstract

A new sarcophagine cage amine ligand with a pendent carboxylate functional group has been synthesised; the ligand has been conjugated to tumour targeting peptides ([Tyr3]-octreotate and [Lys3]-bombesin) and the conjugates radiolabelled with copper-64.

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Year:  2009        PMID： 19587925     DOI： 10.1039/b903426a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

1.  Comparison of (64)Cu-complexing bifunctional chelators for radioimmunoconjugation: labeling efficiency, specific activity, and in vitro/in vivo stability.

Authors:  Maggie S Cooper; Michelle T Ma; Kavitha Sunassee; Karen P Shaw; Jennifer D Williams; Rowena L Paul; Paul S Donnelly; Philip J Blower
Journal:  Bioconjug Chem       Date:  2012-04-13       Impact factor: 4.774

Review 2.  Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease.

Authors:  Thaddeus J Wadas; Edward H Wong; Gary R Weisman; Carolyn J Anderson
Journal:  Chem Rev       Date:  2010-05-12       Impact factor: 60.622

Review 3.  Bombesin receptor-mediated imaging and cytotoxicity: review and current status.

Authors:  Veronica Sancho; Alessia Di Florio; Terry W Moody; Robert T Jensen
Journal:  Curr Drug Deliv       Date:  2011-01       Impact factor: 2.565

4.  Metallic radionuclides in the development of diagnostic and therapeutic radiopharmaceuticals.

Authors:  Sibaprasad Bhattacharyya; Manish Dixit
Journal:  Dalton Trans       Date:  2011-05-03       Impact factor: 4.390

5.  In vitro and in vivo evaluation of 64Cu-labeled SarAr-bombesin analogs in gastrin-releasing peptide receptor-expressing prostate cancer.

Authors:  Kimberly A Lears; Riccardo Ferdani; Kexian Liang; Alexander Zheleznyak; Rebecca Andrews; Christopher D Sherman; Samuel Achilefu; Carolyn J Anderson; Buck E Rogers
Journal:  J Nucl Med       Date:  2011-02-14       Impact factor: 10.057

6.  New Bifunctional Chelator p-SCN-PhPr-NE3TA for Copper-64: Synthesis, Peptidomimetic Conjugation, Radiolabeling, and Evaluation for PET Imaging.

Authors:  Yongkang Gai; Lingyi Sun; Wenqi Hui; Qin Ouyang; Carolyn J Anderson; Guangya Xiang; Xiang Ma; Dexing Zeng
Journal:  Inorg Chem       Date:  2016-06-27       Impact factor: 5.165

Review 7.  A nuclear chocolate box: the periodic table of nuclear medicine.

Authors:  Philip J Blower
Journal:  Dalton Trans       Date:  2015-03-21       Impact factor: 4.390

8.  Total chemical synthesis of a heterodimeric interchain bis-lactam-linked Peptide: application to an analogue of human insulin-like Peptide 3.

Authors:  John Karas; Fazel Shabanpoor; Mohammed Akhter Hossain; James Gardiner; Frances Separovic; John D Wade; Denis B Scanlon
Journal:  Int J Pept       Date:  2013-10-28

Review 9.  Chelators for copper radionuclides in positron emission tomography radiopharmaceuticals.

Authors:  Zhengxin Cai; Carolyn J Anderson
Journal:  J Labelled Comp Radiopharm       Date:  2013-12-18       Impact factor: 1.921

10.  New Bifunctional Chelators Incorporating Dibromomaleimide Groups for Radiolabeling of Antibodies with Positron Emission Tomography Imaging Radioisotopes.

Authors:  Matthew Farleigh; Truc Thuy Pham; Zilin Yu; Jana Kim; Kavitha Sunassee; George Firth; Nafsika Forte; Vijay Chudasama; James R Baker; Nicholas J Long; Charlotte Rivas; Michelle T Ma
Journal:  Bioconjug Chem       Date:  2021-03-16       Impact factor: 4.774
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