Literature DB >> 24347474

Chelators for copper radionuclides in positron emission tomography radiopharmaceuticals.

Zhengxin Cai1, Carolyn J Anderson.   

Abstract

The development of chelating agents for copper radionuclides in positron emission tomography radiopharmaceuticals has been a highly active and important area of study in recent years. The rapid evolution of chelators has resulted in highly specific copper chelators that can be readily conjugated to biomolecules and efficiently radiolabeled to form stable complexes in vivo. Chelators are not only designed for conjugation to monovalent biomolecules but also for incorporation into multivalent targeting ligands such as theranostic nanoparticles. These advancements have strengthened the role of copper radionuclides in the fields of nuclear medicine and molecular imaging. This review emphasizes developments of new copper chelators that have most greatly advanced the field of copper-based radiopharmaceuticals over the past 5 years.
© 2013 The Authors. J. Label Compd. Radiopharm published by John Wiley & Sons Ltd.

Entities:  

Keywords:  PET; chelator; copper 64; molecular imaging; radiopharmaceutical

Mesh：

Substances：

Year:  2013        PMID： 24347474      PMCID： PMC4277819          DOI： 10.1002/jlcr.3165

Source DB:  PubMed          Journal:  J Labelled Comp Radiopharm        ISSN： 0362-4803            Impact factor:   1.921


  58 in total

1.  Preparation and biological evaluation of (64)Cu labeled Tyr(3)-octreotate using a phosphonic acid-based cross-bridged macrocyclic chelator.

Authors:  Yunjun Guo; Riccardo Ferdani; Carolyn J Anderson
Journal:  Bioconjug Chem       Date:  2012-06-18       Impact factor: 4.774

2.  "Click to chelate": synthesis and installation of metal chelates into biomolecules in a single step.

Authors:  Thomas L Mindt; Harriet Struthers; Luc Brans; Todor Anguelov; Christian Schweinsberg; Veronique Maes; Dirk Tourwé; Roger Schibli
Journal:  J Am Chem Soc       Date:  2006-11-29       Impact factor: 15.419

3.  A practical guide to the construction of radiometallated bioconjugates for positron emission tomography.

Authors:  Brian M Zeglis; Jason S Lewis
Journal:  Dalton Trans       Date:  2011-03-25       Impact factor: 4.390

4.  64Cu-TETA-octreotide as a PET imaging agent for patients with neuroendocrine tumors.

Authors:  C J Anderson; F Dehdashti; P D Cutler; S W Schwarz; R Laforest; L A Bass; J S Lewis; D W McCarthy
Journal:  J Nucl Med       Date:  2001-02       Impact factor: 10.057

Review 5.  Copper chelation chemistry and its role in copper radiopharmaceuticals.

Authors:  T J Wadas; E H Wong; G R Weisman; C J Anderson
Journal:  Curr Pharm Des       Date:  2007       Impact factor: 3.116

Review 6.  Sarar technology for the application of Copper-64 in biology and materials science.

Authors:  S V Smith
Journal:  Q J Nucl Med Mol Imaging       Date:  2008-01-05       Impact factor: 2.346

Review 7.  Decay data and production yields of some non-standard positron emitters used in PET.

Authors:  S M Qaim
Journal:  Q J Nucl Med Mol Imaging       Date:  2008-01-05       Impact factor: 2.346

Review 8.  Cross-bridged macrocyclic chelators for stable complexation of copper radionuclides for PET imaging.

Authors:  C J Anderson; T J Wadas; E H Wong; G R Weisman
Journal:  Q J Nucl Med Mol Imaging       Date:  2007-11-28       Impact factor: 2.346

9.  Synthesis of novel 1,4,7,10-tetraazacyclodecane-1,4,7,10-tetraacetic acid (DOTA) derivatives for chemoselective attachment to unprotected polyfunctionalized compounds.

Authors:  Sebastian Knör; Armin Modlinger; Thorsten Poethko; Margret Schottelius; Hans-Jürgen Wester; Horst Kessler
Journal:  Chemistry       Date:  2007       Impact factor: 5.236

10.  Imparting multivalency to a bifunctional chelator: a scaffold design for targeted PET imaging probes.

Authors:  Wei Liu; Guiyang Hao; Michael A Long; Tiffani Anthony; Jer-Tsong Hsieh; Xiankai Sun
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336
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  25 in total

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Authors:  Zhengxin Cai; Barbara T Y Li; Edward H Wong; Gary R Weisman; Carolyn J Anderson
Journal:  Dalton Trans       Date:  2015-03-07       Impact factor: 4.390

Review 2.  Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes.

Authors:  Reik Löser; Jens Pietzsch
Journal:  Front Chem       Date:  2015-06-23       Impact factor: 5.221

Review 3.  High-Throughput Approaches to the Development of Molecular Imaging Agents.

Authors:  Lina Y Hu; Kimberly A Kelly; Julie L Sutcliffe
Journal:  Mol Imaging Biol       Date:  2017-04       Impact factor: 3.488

4.  PET Imaging of HER2-Positive Tumors with Cu-64-Labeled Affibody Molecules.

Authors:  Shibo Qi; Susan Hoppmann; Yingding Xu; Zhen Cheng
Journal:  Mol Imaging Biol       Date:  2019-10       Impact factor: 3.488

5.  Evaluation of Cu-64 and Ga-68 Radiolabeled Glucagon-Like Peptide-1 Receptor Agonists as PET Tracers for Pancreatic β cell Imaging.

Authors:  Nilantha Bandara; Alex Zheleznyak; Kaavya Cherukuri; David A Griffith; Chris Limberakis; David A Tess; Chen Jianqing; Rikki Waterhouse; Suzanne E Lapi
Journal:  Mol Imaging Biol       Date:  2016-02       Impact factor: 3.488

6.  Chelation of Theranostic Copper Radioisotopes with S-Rich Macrocycles: From Radiolabelling of Copper-64 to In Vivo Investigation.

Authors:  Marianna Tosato; Marco Verona; Chiara Favaretto; Marco Pometti; Giordano Zanoni; Fabrizio Scopelliti; Francesco Paolo Cammarata; Luca Morselli; Zeynep Talip; Nicholas P van der Meulen; Valerio Di Marco; Mattia Asti
Journal:  Molecules       Date:  2022-06-28       Impact factor: 4.927

7.  Revisiting dithiadiaza macrocyclic chelators for copper-64 PET imaging.

Authors:  Sergey Shuvaev; Elizaveta A Suturina; Nicholas J Rotile; Andrei Astashkin; Christopher J Ziegler; Alana W Ross; Tia L Walker; Peter Caravan; Ian S Taschner
Journal:  Dalton Trans       Date:  2020-10-20       Impact factor: 4.390

Review 8.  Peptide-based fibrin-targeting probes for thrombus imaging.

Authors:  Bruno L Oliveira; Peter Caravan
Journal:  Dalton Trans       Date:  2017-10-31       Impact factor: 4.390

9.  Promising bifunctional chelators for copper 64-PET imaging: practical (64)Cu radiolabeling and high in vitro and in vivo complex stability.

Authors:  Ningjie Wu; Chi Soo Kang; Inseok Sin; Siyuan Ren; Dijie Liu; Varyanna C Ruthengael; Michael R Lewis; Hyun-Soon Chong
Journal:  J Biol Inorg Chem       Date:  2015-12-14       Impact factor: 3.358

Review 10.  A nuclear chocolate box: the periodic table of nuclear medicine.

Authors:  Philip J Blower
Journal:  Dalton Trans       Date:  2015-03-21       Impact factor: 4.390
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