Literature DB >> 195749

[Intestinal vasoactive peptide receptors in enterocytes : specific binding and stimulation of cyclic AMP].

M Laburthe, J Besson, D H Bon Hoa, G Rosselin.   

Abstract

Receptors for the vasoactive intestinal peptide (VIP) were characterized on enterocytes isolated from Rat small intestine. Native VIP inhibited competitively the binding of 125I-VIP to enterocytes and strongly stimulated cyclic AMP production; both these effects were observed for concentrations of VIP as low as 0.5-1.0 ng/ml (0.15-0.30 nM) which are compatible with the VIP concentration in the gut.

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Year:  1977        PMID： 195749

Source DB:  PubMed          Journal:  C R Acad Hebd Seances Acad Sci D


  9 in total

1.  Vasoactive intestinal polypeptide promotes cyclic adenosine 3',5'-monophosphate accumulation in guinea-pig trachea.

Authors:  E K Frandsen; G A Krishna; S I Said
Journal:  Br J Pharmacol       Date:  1978-03       Impact factor: 8.739

2.  Vasoactive intestinal peptide: a potent stimulator of adenosine 3':5'-cyclic monophosphate accumulation in gut carcinoma cell lines in culture.

Authors:  M Laburthe; M Rousset; C Boissard; G Chevalier; A Zweibaum; G Rosselin
Journal:  Proc Natl Acad Sci U S A       Date:  1978-06       Impact factor: 11.205

3.  Vasoactive intestinal polypeptide: specific binding to rat brain membranes.

Authors:  D P Taylor; C B Pert
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

Review 4.  Vasoactive intestinal peptide.

Authors:  S I Said
Journal:  J Endocrinol Invest       Date:  1986-04       Impact factor: 4.256

5.  Evidence for the presence of insulin binding sites in isolated rat intestinal epithelial cells.

Authors:  M E Forgue-Lafitte; M R Marescot; M C Chamblier; G Rosselin
Journal:  Diabetologia       Date:  1980-10       Impact factor: 10.122

6.  Vasoactive intestinal polypeptide (VIP) as a mediator of the watery diarrhea syndrome.

Authors:  S I Said
Journal:  World J Surg       Date:  1979-09-20       Impact factor: 3.352

7.  Influence of vasoactive intestinal polypeptide on net water flux and cyclic adenosine 3',5'-monophosphate formation in the rat jejunum.

Authors:  E Beubler
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1980-09       Impact factor: 3.000

8.  Importance of the vasoactive intestinal peptide receptor in the stimulation of cyclic adenosine 3',5'-monophosphate in gallbladder epithelial cells of man. Comparison with the guinea pig.

Authors:  C Dupont; J P Broyart; Y Broer; B Chenut; M Laburthe; G Rosselin
Journal:  J Clin Invest       Date:  1981-03       Impact factor: 14.808

9.  A new bioassay of VIP: results in watery diarrhoea syndrome.

Authors:  M C Laburthe; C M Dupont; J D Besson; M Rousset; G E Rosselin
Journal:  Gut       Date:  1980-07       Impact factor: 23.059
  9 in total

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