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Literature DB >> 205290

Vasoactive intestinal polypeptide promotes cyclic adenosine 3',5'-monophosphate accumulation in guinea-pig trachea.

Abstract

Cyclic adenosine 3',5'-monophosphage (cyclic AMP) levels in guinea-pig tracheal rings increased on incubation with the vasoactive intestinal peptide (VIP). The effect was potentiated by the addition of theophylline. The results suggest that the tracheo-bronchial relaxant action of VIP may be mediated by stimulation of tracheal adenylyl cyclase.

Entities: Chemical Gene Species

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Year: 1978 PMID： 205290 PMCID： PMC1668193 DOI： 10.1111/j.1476-5381.1978.tb08471.x

Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739

14 in total

1. Vasoactive intestinal peptide stimulation of adenylate cyclase and active electrolyte secretion in intestinal mucosa.

Authors: C J Schwartz; D V Kimberg; H E Sheerin; M Field; S I Said
Journal: J Clin Invest Date: 1974-09 Impact factor: 14.808

2. Humoral control of airways.

Authors: S I Said; S Kitamura; T Yoshida; J Preskitt; L D Holden
Journal: Ann N Y Acad Sci Date: 1974 Impact factor: 5.691

3. Vasoactive intestinal polypeptide and glucagon: stimulation of adenylate cyclase activity via distinct receptors in liver and fat cell membranes.

Authors: B Desbuguois; M H Laudat; P Laudat
Journal: Biochem Biophys Res Commun Date: 1973-08-21 Impact factor: 3.575

4. Effects on smooth muscle preparations of unidentified vasoactiv peptides from intestine and lung.

Authors: P J Piper; S I Said; J R Vane
Journal: Nature Date: 1970-03-21 Impact factor: 49.962

5. Lipolytic action of a newly isolated vasoactive intestinal polypeptide.

Authors: E K Frandsen; A J Moody
Journal: Horm Metab Res Date: 1973-05 Impact factor: 2.936

6. Relationship of spasmogenic and smooth muscle relaxant peptides from normal lung to other vasoactive compounds.

Authors: S I Said; V Mutt
Journal: Nature Date: 1977-01-06 Impact factor: 49.962

7. Mechanism of action of some bronchodilators. Cyclic nucleotide metabolism in tracheal preparations.

Authors: F Murad
Journal: Am Rev Respir Dis Date: 1974-12

8. Effect of trimetoquinol on the cyclic AMP level in the tracheal muscle of guinea-pig.

Authors: M Inamasu; A Shinjo; Y Iwasawa; T Morita
Journal: Biochem Pharmacol Date: 1974-11-15 Impact factor: 5.858

9. [Intestinal vasoactive peptide receptors in enterocytes : specific binding and stimulation of cyclic AMP].

Authors: M Laburthe; J Besson; D H Bon Hoa; G Rosselin
Journal: C R Acad Hebd Seances Acad Sci D Date: 1977-06-06

10. Cyclic 3',5'-adenosine monophosphate and bronchial tone.

Authors: L Triner; Y Vulliemoz; M Verosky
Journal: Eur J Pharmacol Date: 1977-01-07 Impact factor: 4.432

8 in total

1. Stimulation of sodium pump by vasoactive intestinal peptide in guinea-pig isolated trachea: potential contribution to mechanisms underlying relaxation of smooth muscle.

Authors: K J Morrison; P M Vanhoutte
Journal: Br J Pharmacol Date: 1996-06 Impact factor: 8.739

Review 2. Noradrenergic inhibitory innervation of the lung.

Authors: J B Richardson
Journal: Lung Date: 1981 Impact factor: 2.584

3. The third nervous system in the lung: physiology and clinical perspectives.

Authors: P J Barnes
Journal: Thorax Date: 1984-08 Impact factor: 9.139

4. Effect of kainic acid injections and other brain lesions on vasoactive intestinal peptide (VIP)-stimulated formation of cAMP in rat brain.

Authors: M Quik; P C Emson; J Fahrenkrug; L L Iversen
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 1979-04 Impact factor: 3.000