Literature DB >> 19559477

NECT trial: more than a small victory over sleeping sickness.

Jimmy Opigo1, Charles Woodrow.   

Abstract

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Year:  2009        PMID： 19559477     DOI： 10.1016/S0140-6736(09)61163-6

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


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  10 in total

1.  Induction of oxidative stress in Trypanosoma brucei by the antitrypanosomal dihydroquinoline OSU-40.

Authors:  Shanshan He; Alex Dayton; Periannan Kuppusamy; Karl A Werbovetz; Mark E Drew
Journal:  Antimicrob Agents Chemother       Date:  2012-02-06       Impact factor: 5.191

Review 2.  [Parasitic diseases of the central nervous system].

Authors:  E Schmutzhard
Journal:  Nervenarzt       Date:  2010-02       Impact factor: 1.214

3.  Computer-aided discovery of Trypanosoma brucei RNA-editing terminal uridylyl transferase 2 inhibitors.

Authors:  Ozlem Demir; Mehdi Labaied; Chris Merritt; Ken Stuart; Rommie E Amaro
Journal:  Chem Biol Drug Des       Date:  2014-06-05       Impact factor: 2.817

Review 4.  NECT is next: implementing the new drug combination therapy for Trypanosoma brucei gambiense sleeping sickness.

Authors:  Oliver Yun; Gerardo Priotto; Jacqueline Tong; Laurence Flevaud; François Chappuis
Journal:  PLoS Negl Trop Dis       Date:  2010-05-25

5.  A molecular mechanism for eflornithine resistance in African trypanosomes.

Authors:  Isabel M Vincent; Darren Creek; David G Watson; Mohammed A Kamleh; Debra J Woods; Pui Ee Wong; Richard J S Burchmore; Michael P Barrett
Journal:  PLoS Pathog       Date:  2010-11-24       Impact factor: 6.823

6.  Fexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness.

Authors:  Els Torreele; Bernadette Bourdin Trunz; David Tweats; Marcel Kaiser; Reto Brun; Guy Mazué; Michael A Bray; Bernard Pécoul
Journal:  PLoS Negl Trop Dis       Date:  2010-12-21

7.  Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis.

Authors:  Jean Rodgers; Amy Jones; Stéphane Gibaud; Barbara Bradley; Christopher McCabe; Michael P Barrett; George Gettinby; Peter G E Kennedy
Journal:  PLoS Negl Trop Dis       Date:  2011-09-06

8.  SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis.

Authors:  Robert T Jacobs; Bakela Nare; Stephen A Wring; Matthew D Orr; Daitao Chen; Jessica M Sligar; Matthew X Jenks; Robert A Noe; Tana S Bowling; Luke T Mercer; Cindy Rewerts; Eric Gaukel; Jennifer Owens; Robin Parham; Ryan Randolph; Beth Beaudet; Cyrus J Bacchi; Nigel Yarlett; Jacob J Plattner; Yvonne Freund; Charles Ding; Tsutomu Akama; Y-K Zhang; Reto Brun; Marcel Kaiser; Ivan Scandale; Robert Don
Journal:  PLoS Negl Trop Dis       Date:  2011-06-28

9.  Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes.

Authors:  Geoffrey M Attardo; Adly M M Abd-Alla; Alvaro Acosta-Serrano; James E Allen; Rosemary Bateta; Joshua B Benoit; Kostas Bourtzis; Jelle Caers; Guy Caljon; Mikkel B Christensen; David W Farrow; Markus Friedrich; Aurélie Hua-Van; Emily C Jennings; Denis M Larkin; Daniel Lawson; Michael J Lehane; Vasileios P Lenis; Ernesto Lowy-Gallego; Rosaline W Macharia; Anna R Malacrida; Heather G Marco; Daniel Masiga; Gareth L Maslen; Irina Matetovici; Richard P Meisel; Irene Meki; Veronika Michalkova; Wolfgang J Miller; Patrick Minx; Paul O Mireji; Lino Ometto; Andrew G Parker; Rita Rio; Clair Rose; Andrew J Rosendale; Omar Rota-Stabelli; Grazia Savini; Liliane Schoofs; Francesca Scolari; Martin T Swain; Peter Takáč; Chad Tomlinson; George Tsiamis; Jan Van Den Abbeele; Aurelien Vigneron; Jingwen Wang; Wesley C Warren; Robert M Waterhouse; Matthew T Weirauch; Brian L Weiss; Richard K Wilson; Xin Zhao; Serap Aksoy
Journal:  Genome Biol       Date:  2019-09-02       Impact factor: 13.583

10.  Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign.

Authors:  Melissa L Sykes; Jonathan B Baell; Marcel Kaiser; Eric Chatelain; Sarah R Moawad; Danny Ganame; Jean-Robert Ioset; Vicky M Avery
Journal:  PLoS Negl Trop Dis       Date:  2012-11-29
  10 in total

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