Literature DB >> 19557077

High marks for GWAS.

Stephen Chanock1.   

Abstract

Two genome-wide association studies for testicular cancer report associations at three new loci, including two candidate genes previously implicated in testicular development, KITLG (ligand for the receptor tyrosine kinase) and SPRY4 (sprouty 4). These studies are notable for the high effect sizes detected and the biological plausibility of the candidate genes.

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Year:  2009        PMID： 19557077      PMCID： PMC6310064          DOI： 10.1038/ng0709-765

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  9 in total

1.  Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration.

Authors:  Christopher Runyan; Kyle Schaible; Kathleen Molyneaux; Zhuoqiao Wang; Linda Levin; Christopher Wylie
Journal:  Development       Date:  2006-11-15       Impact factor: 6.868

Review 2.  Beyond odds ratios--communicating disease risk based on genetic profiles.

Authors:  Peter Kraft; Sholom Wacholder; Marilyn C Cornelis; Frank B Hu; Richard B Hayes; Gilles Thomas; Robert Hoover; David J Hunter; Stephen Chanock
Journal:  Nat Rev Genet       Date:  2009-04       Impact factor: 53.242

3.  Common genetic variation and human traits.

Authors:  David B Goldstein
Journal:  N Engl J Med       Date:  2009-04-15       Impact factor: 91.245

Review 4.  A HapMap harvest of insights into the genetics of common disease.

Authors:  Teri A Manolio; Lisa D Brooks; Francis S Collins
Journal:  J Clin Invest       Date:  2008-05       Impact factor: 14.808

5.  Risks of breast and testicular cancers in young adult twins in England and Wales: evidence on prenatal and genetic aetiology.

Authors:  A J Swerdlow; B L De Stavola; M A Swanwick; N E Maconochie
Journal:  Lancet       Date:  1997-12-13       Impact factor: 79.321

6.  Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.

Authors:  Peter A Kanetsky; Nandita Mitra; Saran Vardhanabhuti; Mingyao Li; David J Vaughn; Richard Letrero; Stephanie L Ciosek; David R Doody; Lauren M Smith; Joellen Weaver; Anthony Albano; Chu Chen; Jacqueline R Starr; Daniel J Rader; Andrew K Godwin; Muredach P Reilly; Hakon Hakonarson; Stephen M Schwartz; Katherine L Nathanson
Journal:  Nat Genet       Date:  2009-05-31       Impact factor: 38.330

7.  Genome-wide association studies in cancer.

Authors:  Douglas F Easton; Rosalind A Eeles
Journal:  Hum Mol Genet       Date:  2008-10-15       Impact factor: 6.150

8.  A genome-wide association study of testicular germ cell tumor.

Authors:  Elizabeth A Rapley; Clare Turnbull; Ali Amin Al Olama; Emmanouil T Dermitzakis; Rachel Linger; Robert A Huddart; Anthony Renwick; Deborah Hughes; Sarah Hines; Sheila Seal; Jonathan Morrison; Jeremie Nsengimana; Panagiotis Deloukas; Nazneen Rahman; D Timothy Bishop; Douglas F Easton; Michael R Stratton
Journal:  Nat Genet       Date:  2009-05-31       Impact factor: 38.330

9.  Familial risk in testicular cancer as a clue to a heritable and environmental aetiology.

Authors:  K Hemminki; X Li
Journal:  Br J Cancer       Date:  2004-05-04       Impact factor: 7.640
  9 in total
  15 in total

Review 1.  A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.

Authors:  John P A Ioannidis; Peter Castaldi; Evangelos Evangelou
Journal:  J Natl Cancer Inst       Date:  2010-05-26       Impact factor: 13.506

2.  A stratified genetic risk assessment for testicular cancer.

Authors:  C P Kratz; M H Greene; G Bratslavsky; J Shi
Journal:  Int J Androl       Date:  2011-05-12

Review 3.  Familial testicular germ cell tumours.

Authors:  Christian P Kratz; Phuong L Mai; Mark H Greene
Journal:  Best Pract Res Clin Endocrinol Metab       Date:  2010-06       Impact factor: 4.690

4.  Structural variation in two human genomes mapped at single-nucleotide resolution by whole genome de novo assembly.

Authors:  Yingrui Li; Hancheng Zheng; Ruibang Luo; Honglong Wu; Hongmei Zhu; Ruiqiang Li; Hongzhi Cao; Boxin Wu; Shujia Huang; Haojing Shao; Hanzhou Ma; Fan Zhang; Shuijian Feng; Wei Zhang; Hongli Du; Geng Tian; Jingxiang Li; Xiuqing Zhang; Songgang Li; Lars Bolund; Karsten Kristiansen; Adam J de Smith; Alexandra I F Blakemore; Lachlan J M Coin; Huanming Yang; Jian Wang; Jun Wang
Journal:  Nat Biotechnol       Date:  2011-07-24       Impact factor: 54.908

5.  Genome-wide association studies in cancer--current and future directions.

Authors:  Charles C Chung; Wagner C S Magalhaes; Jesus Gonzalez-Bosquet; Stephen J Chanock
Journal:  Carcinogenesis       Date:  2009-11-11       Impact factor: 4.944

6.  Discover novel disease-associated genes based on regulatory networks of long-range chromatin interactions.

Authors:  Hao Wang; Jiaxin Yang; Yu Zhang; Jianrong Wang
Journal:  Methods       Date:  2020-10-21       Impact factor: 3.608

Review 7.  The genomic landscape of testicular germ cell tumours: from susceptibility to treatment.

Authors:  Kevin Litchfield; Max Levy; Robert A Huddart; Janet Shipley; Clare Turnbull
Journal:  Nat Rev Urol       Date:  2016-06-14       Impact factor: 14.432

8.  Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.

Authors:  Mark P Purdue; Mattias Johansson; Diana Zelenika; Jorge R Toro; Ghislaine Scelo; Lee E Moore; Egor Prokhortchouk; Xifeng Wu; Lambertus A Kiemeney; Valerie Gaborieau; Kevin B Jacobs; Wong-Ho Chow; David Zaridze; Vsevolod Matveev; Jan Lubinski; Joanna Trubicka; Neonila Szeszenia-Dabrowska; Jolanta Lissowska; Péter Rudnai; Eleonora Fabianova; Alexandru Bucur; Vladimir Bencko; Lenka Foretova; Vladimir Janout; Paolo Boffetta; Joanne S Colt; Faith G Davis; Kendra L Schwartz; Rosamonde E Banks; Peter J Selby; Patricia Harnden; Christine D Berg; Ann W Hsing; Robert L Grubb; Heiner Boeing; Paolo Vineis; Françoise Clavel-Chapelon; Domenico Palli; Rosario Tumino; Vittorio Krogh; Salvatore Panico; Eric J Duell; José Ramón Quirós; Maria-José Sanchez; Carmen Navarro; Eva Ardanaz; Miren Dorronsoro; Kay-Tee Khaw; Naomi E Allen; H Bas Bueno-de-Mesquita; Petra H M Peeters; Dimitrios Trichopoulos; Jakob Linseisen; Börje Ljungberg; Kim Overvad; Anne Tjønneland; Isabelle Romieu; Elio Riboli; Anush Mukeria; Oxana Shangina; Victoria L Stevens; Michael J Thun; W Ryan Diver; Susan M Gapstur; Paul D Pharoah; Douglas F Easton; Demetrius Albanes; Stephanie J Weinstein; Jarmo Virtamo; Lars Vatten; Kristian Hveem; Inger Njølstad; Grethe S Tell; Camilla Stoltenberg; Rajiv Kumar; Kvetoslava Koppova; Olivier Cussenot; Simone Benhamou; Egbert Oosterwijk; Sita H Vermeulen; Katja K H Aben; Saskia L van der Marel; Yuanqing Ye; Christopher G Wood; Xia Pu; Alexander M Mazur; Eugenia S Boulygina; Nikolai N Chekanov; Mario Foglio; Doris Lechner; Ivo Gut; Simon Heath; Hélène Blanche; Amy Hutchinson; Gilles Thomas; Zhaoming Wang; Meredith Yeager; Joseph F Fraumeni; Konstantin G Skryabin; James D McKay; Nathaniel Rothman; Stephen J Chanock; Mark Lathrop; Paul Brennan
Journal:  Nat Genet       Date:  2010-12-05       Impact factor: 38.330

9.  A polymorphic p53 response element in KIT ligand influences cancer risk and has undergone natural selection.

Authors:  Jorge Zeron-Medina; Xuting Wang; Emmanouela Repapi; Michelle R Campbell; Dan Su; Francesc Castro-Giner; Benjamin Davies; Elisabeth F P Peterse; Natalia Sacilotto; Graeme J Walker; Tamara Terzian; Ian P Tomlinson; Neil F Box; Nicolai Meinshausen; Sarah De Val; Douglas A Bell; Gareth L Bond
Journal:  Cell       Date:  2013-10-10       Impact factor: 41.582

10.  Age-specific incidence data indicate four mutations are required for human testicular cancers.

Authors:  James P Brody
Journal:  PLoS One       Date:  2011-10-06       Impact factor: 3.240
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