Literature DB >> 19553112

Discovery and optimization of a novel Neuromedin B receptor antagonist.

Jiasheng Fu1, Stephen J Shuttleworth, Richard V Connors, Anne Chai, Peter Coward.   

Abstract

The discovery and parallel synthesis of potent, small molecule antagonists of Neuromedin B receptor based on the ary-hexahydro-dibenzodiazepin-1-one core is described.

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Year:  2009        PMID: 19553112     DOI: 10.1016/j.bmcl.2009.05.124

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

Review 1.  Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2009.

Authors:  Roland E Dolle; Bertrand Le Bourdonnec; Karin Worm; Guillermo A Morales; Craig J Thomas; Wei Zhang
Journal:  J Comb Chem       Date:  2010-10-05

2.  Synthesis of tetracyclic pyrido-fused dibenzodiazepines via a catalyst-free cascade reaction.

Authors:  Abdolali Alizadeh; Akram Bagherinejad
Journal:  Mol Divers       Date:  2020-06-14       Impact factor: 2.943

  2 in total

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