Literature DB >> 19521633

Efficient three-component one-pot synthesis of fully substituted pyridin-2(1H)-ones via tandem Knoevenagel condensation-ring-opening of cyclopropane-intramolecular cyclization.

Fushun Liang1, Xin Cheng, Jing Liu, Qun Liu.   

Abstract

An efficient synthesis of fully substituted pyridin-2(1H)-ones was developed via three-component one-pot reactions of readily available 1-acetyl-1-carbamoyl cyclopropanes, malononitrile and cyclic secondary amines.

Entities:  

Year:  2009        PMID： 19521633     DOI： 10.1039/b905742k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  Efficient and divergent synthesis of polyfunctionalized 2-pyridones from β-keto amides.

Authors:  Baochang Gao; Yufeng Sun; Jun Wang; Zhigang Yuan; Liwu Zu; Xu Zhang; Wenbin Liu
Journal:  RSC Adv       Date:  2018-10-01       Impact factor: 4.036

2.  Ethyl 6-amino-5-cyano-2,4-bis-(4-methyl-phen-yl)-4H-pyran-3-carboxyl-ate.

Authors:  M Kannan; Kandhasamy Kumaravel; Gnanasambandam Vasuki; R Krishna
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-09-11

3.  Ethyl 6-amino-5-cyano-2-methyl-4-propyl-4H-pyran-3-carboxyl-ate.

Authors:  Qun-Di Yu; Ke-Xin Li; Yun-Yu Liu
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-10-28

4.  6-Amino-3,4-dimethyl-4-phenyl-2H,4H-pyrano[2,3-c]pyrazole-5-carbonitrile.

Authors:  Nishith Saurav Topno; Kandhasamy Kumaravel; M Kannan; Gnanasambandam Vasuki; R Krishna
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-03-23

5.  4-(4-Fluoro-phen-yl)-6-methyl-amino-5-nitro-2-phenyl-4H-pyran-3-carbo-nitrile.

Authors:  R Vishnupriya; J Suresh; S Sivakumar; R Ranjith Kumar; P L Nilantha Lakshman
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-04-10
  5 in total

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