| Literature DB >> 19521522 |
Yun Luo1, Masaru Higa, Shintaro Amae, Tomoyuki Yambe, Takeshi Okuyama, Toshiyuki Takagi, Hidetoshi Matsuki.
Abstract
Severe dysfunction of muscle tissues can be treated by transplantation but the success rate is still not high enough. One possibility instead is to replace the dysfunctional muscle with artificial muscles. This article introduces a unique approach using shape memory alloys (SMAs) to replace the anal sphincter muscle for solving the problem of fecal incontinence. The use of SMAs that exhibit a two-way shape memory effect allows the device to function like a sphincter muscle and facilitates simple design. In this article, we will give a brief introduction to the functional material-SMA-together with its medical applications, and will follow this with a description of the recent progress in research and development of an SMA-based artificial sphincter. The possibility of its commercialization will also be discussed.Entities:
Keywords: anal sphincter; artificial muscle; artificial organ; fecal incontinence; shape memory alloy; tissue reconstruction
Year: 2005 PMID: 19521522 PMCID: PMC2645520 DOI: 10.4161/org.2.1.1757
Source DB: PubMed Journal: Organogenesis ISSN: 1547-6278 Impact factor: 2.500