| Literature DB >> 19506575 |
Wolf H Rogowski1, Scott D Grosse, Muin J Khoury.
Abstract
Research in genetics and genomics has led to an expanding list of molecular genetic tests, which are increasingly entering health care systems. However, the evidence surrounding the benefits and harms of these tests is frequently weak. Here we present the main challenges to the successful translation of new research findings about genotype-phenotype associations into clinical practice. We discuss the means to achieve an accelerated translation research agenda that is conducted in a reasonable, fair and efficient manner.Mesh:
Year: 2009 PMID: 19506575 DOI: 10.1038/nrg2606
Source DB: PubMed Journal: Nat Rev Genet ISSN: 1471-0056 Impact factor: 53.242