Literature DB >> 19502068

Synthesis, antioxidant properties and radioprotective effects of new benzothiazoles and thiadiazoles.

Damien Cressier1, Caroline Prouillac, Pierre Hernandez, Christine Amourette, Michel Diserbo, Claude Lion, Ghassoub Rima.   

Abstract

In this work, we report the synthesis and characterization of new compounds derived from benzothiazoles and thiadiazoles. We observed that structural modifications on these skeletons affected the antioxidant activity. Thiol and aminothiol compounds derived from thiadiazoles and benzothiazoles showed an interesting antioxidant property. The radioprotective activity has also been evaluated in mice. Some of these compounds could be good radioprotectors.

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Year:  2009        PMID： 19502068     DOI： 10.1016/j.bmc.2009.05.039

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  18 in total

1.  Redox regulation of neurovascular function by acetazolamide: complementary insight into mechanisms underlying high-altitude acclimatisation.

Authors:  Damian M Bailey; Julien V Brugniaux; Sylvia Pietri; Marcel Culcasi; Erik R Swenson
Journal:  J Physiol       Date:  2012-08-01       Impact factor: 5.182

2.  An integrated approach towards the development of novel antifungal agents containing thiadiazole: synthesis and a combined similarity search, homology modelling, molecular dynamics and molecular docking study.

Authors:  Mustafa Er; Abdulati Miftah Abounakhla; Hakan Tahtaci; Ali Hasin Bawah; Süleyman Selim Çınaroğlu; Abdurrahman Onaran; Abdulilah Ece
Journal:  Chem Cent J       Date:  2018-11-23       Impact factor: 4.215

3.  'Click' synthesis of dextran macrostructures for combinatorial-designed self-assembled nanoparticles encapsulating diverse anticancer therapeutics.

Authors:  Sampath C Abeylath; Mansoor M Amiji
Journal:  Bioorg Med Chem       Date:  2011-09-17       Impact factor: 3.641

4.  Synthesis, Characterization, and Biological Evaluation of certain 6-methyl-2(3H)-benzo-1, 3-thiazolyl-1'-ethylidene-2-(o, p- Substituted Acetophenones) Hydrazine Analogs.

Authors:  G Alang; G Kaur; R Kaur; A Singh; R Tiwari
Journal:  J Young Pharm       Date:  2010-10

5.  5-({[(E)-Benzyl-idene-amino]-oxy}meth-yl)-1,3,4-thia-diazol-2-amine.

Authors:  Weiyan Yin; Zhi Wang; Zi-Wen Yang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-02-17

6.  2,2'-[(1,3,4-Thia-diazole-2,5-di-yl)bis-(sulfanedi-yl)]diaceto-nitrile.

Authors:  Joel T Mague; Mehmet Akkurt; Shaaban K Mohamed; Ahmed M M El-Saghier; Mustafa R Albayati
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-11-30

7.  Synthesis, characterization and RHF/ab initio simulations of 2-amino-1,3,4-thiadiazole and its annulated ring junction pyrimidine derivatives.

Authors:  Wafaa S Hamama; Moustafa A Gouda; Mamdouh S Soliman; Marwa H Badr; Hanafi H Zoorob
Journal:  J Adv Res       Date:  2012-03-09       Impact factor: 10.479

8.  A Fluorinated Phenylbenzothiazole Arrests the Trypanosoma cruzi Cell Cycle and Diminishes the Infection of Mammalian Host Cells.

Authors:  Roberto I Cuevas-Hernández; Richard M B M Girard; Sarai Martínez-Cerón; Marcelo Santos da Silva; Maria Carolina Elias; Marcell Crispim; José G Trujillo-Ferrara; Ariel Mariano Silber
Journal:  Antimicrob Agents Chemother       Date:  2020-01-27       Impact factor: 5.191

9.  Synthesis of benzo[d]thiazole-hydrazone analogues: molecular docking and SAR studies of potential H+/K+ ATPase inhibitors and anti-inflammatory agents.

Authors:  Shi-Meng Wang; Gao-Feng Zha; K P Rakesh; N Darshini; T Shubhavathi; H K Vivek; N Mallesha; Hua-Li Qin
Journal:  Medchemcomm       Date:  2017-04-26       Impact factor: 3.597

10.  EGFR tyrosine kinase targeted compounds: in vitro antitumor activity and molecular modeling studies of new benzothiazole and pyrimido[2,1-b]benzothiazole derivatives.

Authors:  Moustafa T Gabr; Nadia S El-Gohary; Eman R El-Bendary; Mohamed M El-Kerdawy
Journal:  EXCLI J       Date:  2014-05-26       Impact factor: 4.068
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