Release pattern of N-terminal probrain natriuretic peptide after intra-aortic balloon pump counterpulsation: Insights into the effects of mechanical unloading in patients with acute decompensated heart failure.

A 60-year-old man with dilated cardiomyopathy and severe decompensated heart failure was acutely managed with intra-aortic balloon pump (IABP) counterpulsation. The present report shows the release pattern of plasma natriuretic peptides after IABP therapy. Preliminary findings suggest that natriuretic peptide levels can be used to measure adequate ventricular unloading by IABP counterpulsation, and that a significant early decrease in natriuretic peptide levels after IABP therapy may potentially help identify future candidates for cardiac recovery after prolonged circulatory support.