Seungbum Kang1, Jin A Choi, Choun-Ki Joo. 1. Department of Ophthalmology and Visual Science, St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Abstract
PURPOSE: To compare posterior capsular opacification (PCO) in a heparin-surface-modified (HSM) hydrophilic acrylic intraocular lens (IOL) and a hydrophobic acrylic IOL. METHODS:Seventy-eight patients with simple cataract were randomized to receive either the BioVue 3 HSM hydrophilic acrylic IOL (Ophthalmic Innovations International, Ontario, CA, USA) (n = 38) or the SensarAR40e hydrophobic acrylic IOL (AMO, Santa Ana, CA, USA) (n = 40). Another 99 patients with complicated cataract received either the BioVue 3 (n = 49) or the Sensar AR40e IOL (n = 50). Twelve months after surgery, POCOman software was used to analyze digital retroillumination photographs of the PCO. RESULTS: In the simple cataract group, the respective PCO areas, expressed as a percentage and PCO severity scores at 12 months were 6.12% and 0.081 in the BioVue 3 group and 5.91% and 0.075 in the Sensar AR40e group. There was no statistically significant difference in the PCO area or the PCO severity score between the two IOLs (P = 0.631, P = 0.495, respectively). In the complicated cataract group, the respective PCO areas and PCO severity scores were 35.80% and 0.181 in the BioVue 3 group and 27.17% and 0.110 in the Sensar AR40e group. There was no statistically significant difference between the two IOLs (P = 0.147, P = 0.162). CONCLUSION: There was no difference in the degree or severity of PCO between the HSM hydrophilic acrylic IOL and the hydrophobic acrylic IOL groups.
RCT Entities:
PURPOSE: To compare posterior capsular opacification (PCO) in a heparin-surface-modified (HSM) hydrophilic acrylic intraocular lens (IOL) and a hydrophobic acrylic IOL. METHODS: Seventy-eight patients with simple cataract were randomized to receive either the BioVue 3 HSM hydrophilic acrylic IOL (Ophthalmic Innovations International, Ontario, CA, USA) (n = 38) or the Sensar AR40e hydrophobic acrylic IOL (AMO, Santa Ana, CA, USA) (n = 40). Another 99 patients with complicated cataract received either the BioVue 3 (n = 49) or the Sensar AR40e IOL (n = 50). Twelve months after surgery, POCOman software was used to analyze digital retroillumination photographs of the PCO. RESULTS: In the simple cataract group, the respective PCO areas, expressed as a percentage and PCO severity scores at 12 months were 6.12% and 0.081 in the BioVue 3 group and 5.91% and 0.075 in the Sensar AR40e group. There was no statistically significant difference in the PCO area or the PCO severity score between the two IOLs (P = 0.631, P = 0.495, respectively). In the complicated cataract group, the respective PCO areas and PCO severity scores were 35.80% and 0.181 in the BioVue 3 group and 27.17% and 0.110 in the Sensar AR40e group. There was no statistically significant difference between the two IOLs (P = 0.147, P = 0.162). CONCLUSION: There was no difference in the degree or severity of PCO between the HSM hydrophilic acrylic IOL and the hydrophobic acrylic IOL groups.
Authors: P G Ursell; D J Spalton; M V Pande; E J Hollick; S Barman; J Boyce; K Tilling Journal: J Cataract Refract Surg Date: 1998-03 Impact factor: 3.351
Authors: G Beltrame; M L Salvetat; M Chizzolini; G B Driussi; P Busatto; G Di Giorgio; F Barosco Journal: Eur J Ophthalmol Date: 2002 Sep-Oct Impact factor: 2.597