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Literature DB >> 19475598

Symmetry-guided design and fluorous synthesis of a stable and rapidly excreted imaging tracer for (19)F MRI.

Zhong-Xing Jiang¹, Xin Liu, Eun-Kee Jeong, Yihua Bruce Yu.

Abstract

Getting FIT: A bispherical (19)F imaging tracer, (19)FIT, was designed and synthesized. (19)FIT is advantageous over perfluorocarbon-based (19)F imaging agents, as it is not retained in the organs and does not require complex formulation procedures. Imaging agents such as (19)FIT can lead to (19)F magnetic resonance imaging (MRI) playing an important role in drug therapy, analogous to the role played by (1)H MRI in disease diagnosis.

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Year: 2009 PMID： 19475598 PMCID： PMC2873849 DOI： 10.1002/anie.200901005

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

21 in total

1. Out of the shadows--MRI and the Nobel Prize.

Authors: John Gore
Journal: N Engl J Med Date: 2003-12-11 Impact factor: 91.245

Review 2. Snapshot magnetic resonance imaging (Nobel lecture).

Authors: Peter Mansfield
Journal: Angew Chem Int Ed Engl Date: 2004-10-18 Impact factor: 15.336

Review 3. Solubilizing excipients in oral and injectable formulations.

Authors: Robert G Strickley
Journal: Pharm Res Date: 2004-02 Impact factor: 4.200

Review 4. 19F: a versatile reporter for non-invasive physiology and pharmacology using magnetic resonance.

Authors: Jian-xin Yu; Vikram D Kodibagkar; Weina Cui; Ralph P Mason
Journal: Curr Med Chem Date: 2005 Impact factor: 4.530

5. 19F relaxation rate enhancement and frequency shift with Gd-DTPA.

Authors: A V Ratner; S Quay; H H Muller; B B Simpson; R Hurd; S W Young
Journal: Invest Radiol Date: 1989-03 Impact factor: 6.016

6. Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging.

Authors: D A Tomalia; L A Reyna; S Svenson
Journal: Biochem Soc Trans Date: 2007-02 Impact factor: 5.407

7. Gadolinium-modulated 19F signals from perfluorocarbon nanoparticles as a new strategy for molecular imaging.

Authors: Anne M Neubauer; Jacob Myerson; Shelton D Caruthers; Franklin D Hockett; Patrick M Winter; Junjie Chen; Patrick J Gaffney; J David Robertson; Gregory M Lanza; Samuel A Wickline
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8. 19F Magnetic resonance imaging of perfluorooctanoic acid encapsulated in liposome for biodistribution measurement.

Authors: Atsuomi Kimura; Michiko Narazaki; Yoko Kanazawa; Hideaki Fujiwara
Journal: Magn Reson Imaging Date: 2004-07 Impact factor: 2.546

9. Fluorinated blood substitute retention in the rat measured by fluorine-19 magnetic resonance imaging.

Authors: K L Meyer; M J Carvlin; B Mukherji; H A Sloviter; P M Joseph
Journal: Invest Radiol Date: 1992-08 Impact factor: 6.016

10. Self-delivering nanoemulsions for dual fluorine-19 MRI and fluorescence detection.

Authors: Jelena M Janjic; Mangala Srinivas; Deepak K K Kadayakkara; Eric T Ahrens
Journal: J Am Chem Soc Date: 2008-02-12 Impact factor: 15.419

22 in total

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2. Fluorous mixture synthesis of asymmetric dendrimers.

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Journal: J Org Chem Date: 2010-03-19 Impact factor: 4.354

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Review 4. New frontiers and developing applications in 19F NMR.

Authors: Jian-Xin Yu; Rami R Hallac; Srinivas Chiguru; Ralph P Mason
Journal: Prog Nucl Magn Reson Spectrosc Date: 2012-11-02 Impact factor: 9.795

5. Optimize the Separation of Fluorinated Amphiles Using High-Performance Liquid Chromatography.

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6. Fluorinated paramagnetic chelates as potential multi-chromic 19F tracer agents.

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Journal: Chem Commun (Camb) Date: 2011-05-26 Impact factor: 6.222

7. A symmetrical fluorous dendron-cyanine dye-conjugated bimodal nanoprobe for quantitative 19F MRI and NIR fluorescence bioimaging.

Authors: Zhe Wang; Xuyi Yue; Yu Wang; Chunqi Qian; Peng Huang; Marty Lizak; Gang Niu; Fu Wang; Pengfei Rong; Dale O Kiesewetter; Ying Ma; Xiaoyuan Chen
Journal: Adv Healthc Mater Date: 2014-05-02 Impact factor: 9.933

8. Avoiding steric congestion in dendrimer growth through proportionate branching: a twist on da Vinci's rule of tree branching.

Authors: Xuyi Yue; Marc B Taraban; Laura L Hyland; Yihua Bruce Yu
Journal: J Org Chem Date: 2012-10-10 Impact factor: 4.354

9. Design and characterization of a novel fluorinated magnetic resonance imaging agent for functional analysis of bile Acid transporter activity.

Authors: Diana Vivian; Kunrong Cheng; Sandeep Khurana; Su Xu; Valerie Whiterock; Drew Witter; Kimberley A Lentz; Kenneth S Santone; Jean-Pierre Raufman; James E Polli
Journal: Pharm Res Date: 2013-01-15 Impact factor: 4.200

10. Discovery of a (19)F MRI sensitive salinomycin derivative with high cytotoxicity towards cancer cells.

Authors: Qiuyan Shi; Yu Li; Shaowei Bo; Xiaofei Li; Peng Zhao; Qi Liu; Zhigang Yang; Hengjiang Cong; Hexiang Deng; Mingnan Chen; Shizhen Chen; Xin Zhou; Hong Ding; Zhong-Xing Jiang
Journal: Chem Commun (Camb) Date: 2016-03-21 Impact factor: 6.222