Literature DB >> 19465708

Risk of hepatocellular carcinoma in hepatitis B and prevention through treatment.

Morris Sherman1.   

Abstract

Risk factors for the development of hepatocellular carcinoma in patients with chronic hepatitis B virus (HBV) infection are being elucidated. An HBV DNA concentration greater than 10(4) copies/mL is an especially strong predictor of risk in individuals aged 30 years or older, independent of the level of serum alanine aminotransferase (ALT). Other predictors of cancer are HBV genotype, with genotype C imparting an increased risk, and serum ALT values at least two times the upper limit of normal. Viral suppression with continuous lamivudine therapy reduces the risk of complications and delays progression of liver disease as long as response is maintained.

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Year:  2009        PMID： 19465708     DOI： 10.3949/ccjm.76.s3.02

Source DB:  PubMed          Journal:  Cleve Clin J Med        ISSN： 0891-1150            Impact factor:   2.321


  16 in total

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2.  Implication of reported viral hepatitis incidence rate change in Hubei Province, China, between 2004-2010.

Authors:  Ying Hu; Chuanhua Yu; Banghua Chen; Lei Wang
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2012-06-09

Review 3.  Hepatitis B viral load affects prognosis of hepatocellular carcinoma.

Authors:  Su Jong Yu; Yoon Jun Kim
Journal:  World J Gastroenterol       Date:  2014-09-14       Impact factor: 5.742

4.  Graft-versus-host disease: role of inflammation in the development of chromosomal abnormalities of keratinocytes.

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5.  Hepatocellular carcinoma: prevention and therapy.

Authors:  Davendra P S Sohal; Weijing Sun
Journal:  Curr Oncol Rep       Date:  2011-06       Impact factor: 5.075

Review 6.  Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma.

Authors:  Alla Arzumanyan; Helena M G P V Reis; Mark A Feitelson
Journal:  Nat Rev Cancer       Date:  2013-02       Impact factor: 60.716

7.  Preventive effect of Metformin against N-nitrosodiethylamine-initiated hepatocellular carcinoma in rats.

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Review 8.  Occult hepatitis B virus and hepatocellular carcinoma.

Authors:  Teresa Pollicino; Carlo Saitta
Journal:  World J Gastroenterol       Date:  2014-05-28       Impact factor: 5.742

9.  Ruptured hepatocellular carcinoma disguising as heterotopic pregnancy.

Authors:  Qiu N Lee; Gabriel Ayonmigbesimi Akra; Augustus G Kigotho; Mahsa Seyed Ahadi
Journal:  BMJ Case Rep       Date:  2018-02-27

Review 10.  Effects of antiviral therapy on preventing liver tumorigenesis and hepatocellular carcinoma recurrence.

Authors:  Zhong-Ming Tan; Bei-Cheng Sun
Journal:  World J Gastroenterol       Date:  2013-12-21       Impact factor: 5.742
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