Literature DB >> 28480063

Viral hepatitis and hepatocellular carcinoma: etiology and management.

Philippe J Zamor1, Andrew S deLemos1, Mark W Russo1.   

Abstract

Chronic hepatitis B virus (HBV) and chronic hepatitis C virus (HCV) are associated with hepatic fibrosis and development of hepatocellular carcinoma (HCC). There are differences and variation with the incidence of HCC worldwide. Additionally, HCC develops via different pathways with these viral hepatitides. This review outlines the various mechanisms and pathophysiology that contributes to this process. There will also be a review on the recommended screening for HCC. Treatment considerations, which are different for these viruses, will be outlined in this review.

Entities:  

Keywords:  Hepatocellular carcinoma (HCC); chronic hepatitis B; chronic hepatitis C; cirrhosis; sustained virologic response (SVR)

Year:  2017        PMID: 28480063      PMCID: PMC5401856          DOI: 10.21037/jgo.2017.03.14

Source DB:  PubMed          Journal:  J Gastrointest Oncol        ISSN: 2078-6891


  103 in total

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2.  HCV genotype 3 is associated with a higher hepatocellular carcinoma incidence in patients with ongoing viral C cirrhosis.

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Journal:  Ann Intern Med       Date:  2003-02-18       Impact factor: 25.391

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6.  Interferon-alpha and 5-fluorouracil combination therapy after palliative hepatic resection in patients with advanced hepatocellular carcinoma, portal venous tumor thrombus in the major trunk, and multiple nodules.

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Journal:  Cancer       Date:  2007-12-01       Impact factor: 6.860

7.  Hepatitis B virus-associated multistep hepatocarcinogenesis: a stepwise increase in allelic alterations.

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Journal:  Cancer Res       Date:  2008-07-15       Impact factor: 12.701

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Journal:  Hepatology       Date:  2002-11       Impact factor: 17.425

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Authors:  Y Imai; S Kawata; S Tamura; I Yabuuchi; S Noda; M Inada; Y Maeda; Y Shirai; T Fukuzaki; I Kaji; H Ishikawa; Y Matsuda; M Nishikawa; K Seki; Y Matsuzawa
Journal:  Ann Intern Med       Date:  1998-07-15       Impact factor: 25.391

10.  Achieving sustained virologic response after interferon-free hepatitis C virus treatment correlates with hepatic interferon gene expression changes independent of cirrhosis.

Authors:  E G Meissner; A Kohli; K Virtaneva; D Sturdevant; C Martens; S F Porcella; J G McHutchison; H Masur; S Kottilil
Journal:  J Viral Hepat       Date:  2016-02-03       Impact factor: 3.728

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  38 in total

Review 1.  Hepatocellular Carcinoma: Etiology and Current and Future Drugs.

Authors:  Aastha Jindal; Anusha Thadi; Kunwar Shailubhai
Journal:  J Clin Exp Hepatol       Date:  2019-01-25

2.  Hepatocellular metastasis recurrence in liver transplant after treatment with direct antiviral agents.

Authors:  Silvia Maier; Debora Donnini; Laura De Luca; Claudio Avellini; Leonardo Alberto Sechi; Giorgio Soardo
Journal:  Clin J Gastroenterol       Date:  2019-08-13

3.  IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma.

Authors:  Turan Aghayev; Aleksandra M Mazitova; Jennifer R Fang; Sergei I Grivennikov; Ekaterina K Koltsova; Iuliia O Peshkova; Matthew Rausch; Manhsin Hung; Kerry F White; Ricard Masia; Elizaveta K Titerina; Aliia R Fatkhullina; Isabelle Cousineau; Simon Turcotte; Dmitry Zhigarev; Anastasiia Marchenko; Svetlana Khoziainova; Petr Makhov; Yin Fei Tan; Andrew V Kossenkov; David L Wiest; John Stagg; Xin Wei Wang; Kerry S Campbell; Amiran K Dzutsev; Giorgio Trinchieri; Jonathan A Hill
Journal:  Cancer Discov       Date:  2022-08-05       Impact factor: 38.272

4.  SCAMP3 is regulated by miR-128-3p and promotes the metastasis of hepatocellular carcinoma cells through EGFR-MAPK p38 signaling pathway.

Authors:  Le Kang; Ze-Hua Zhang; Ying Zhao
Journal:  Am J Transl Res       Date:  2020-12-15       Impact factor: 4.060

Review 5.  Recent Advances in Anticancer Activity of Novel Plant Extracts and Compounds from Curcuma longa in Hepatocellular Carcinoma.

Authors:  Nighat Gull; Fareeha Arshad; Gowhar A Naikoo; Israr Ul Hassan; Mona Zamani Pedram; Arif Ahmad; Alaa A A Aljabali; Vijay Mishra; Saurabh Satija; Nitin Charbe; Poonam Negi; Rohit Goyal; Ángel Serrano-Aroca; Mazhar S Al Zoubi; Mohamed El-Tanani; Murtaza M Tambuwala
Journal:  J Gastrointest Cancer       Date:  2022-03-14

6.  Hepatitis B virus x protein induces epithelial-mesenchymal transition of hepatocellular carcinoma cells by regulating long non-coding RNA.

Authors:  Yinji Jin; Di Wu; Weiwei Yang; Mingjiao Weng; Yafei Li; Xuefei Wang; Xiao Zhang; Xiaoming Jin; Tianzhen Wang
Journal:  Virol J       Date:  2017-12-19       Impact factor: 4.099

Review 7.  Viral Oncology: Molecular Biology and Pathogenesis.

Authors:  Uyen Ngoc Mui; Christopher T Haley; Stephen K Tyring
Journal:  J Clin Med       Date:  2017-11-29       Impact factor: 4.241

8.  Peretinoin, an acyclic retinoid, inhibits hepatocarcinogenesis by suppressing sphingosine kinase 1 expression in vitro and in vivo.

Authors:  Masaya Funaki; Juria Kitabayashi; Tetsuro Shimakami; Naoto Nagata; Yuriko Sakai; Kai Takegoshi; Hikari Okada; Kazuhisa Murai; Takayoshi Shirasaki; Takeru Oyama; Taro Yamashita; Tsuguhito Ota; Yoh Takuwa; Masao Honda; Shuichi Kaneko
Journal:  Sci Rep       Date:  2017-12-05       Impact factor: 4.379

Review 9.  The Endless Sources of Hepatocellular Carcinoma Heterogeneity.

Authors:  Marina Barcena-Varela; Amaia Lujambio
Journal:  Cancers (Basel)       Date:  2021-05-26       Impact factor: 6.639

Review 10.  HBV Integration Induces Complex Interactions between Host and Viral Genomic Functions at the Insertion Site.

Authors:  Dake Zhang; Ke Zhang; Urlike Protzer; Changqing Zeng
Journal:  J Clin Transl Hepatol       Date:  2021-04-25
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