Literature DB >> 23344543

Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma.

Alla Arzumanyan1, Helena M G P V Reis, Mark A Feitelson.   

Abstract

Hepatocellular carcinoma (HCC) is a highly lethal cancer, with increasing worldwide incidence, that is mainly associated with chronic hepatitis B virus (HBV) and/or hepatitis C virus (HCV) infections. There are few effective treatments partly because the cell- and molecular-based mechanisms that contribute to the pathogenesis of this tumour type are poorly understood. This Review outlines pathogenic mechanisms that seem to be common to both viruses and which suggest innovative approaches to the prevention and treatment of HCC.

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Year:  2013        PMID： 23344543     DOI： 10.1038/nrc3449

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  182 in total

Review 1.  Angiogenic activity of hepatitis B and C viruses.

Authors:  Kristof Vrancken; Jan Paeshuyse; Sandra Liekens
Journal:  Antivir Chem Chemother       Date:  2012-01-17

2.  Subversion of cellular autophagy machinery by hepatitis B virus for viral envelopment.

Authors:  Jianhua Li; Yinghui Liu; Zekun Wang; Kuancheng Liu; Yaohui Wang; Jiangxia Liu; Huanping Ding; Zhenghong Yuan
Journal:  J Virol       Date:  2011-04-20       Impact factor: 5.103

3.  miR-21 promotes migration and invasion by the miR-21-PDCD4-AP-1 feedback loop in human hepatocellular carcinoma.

Authors:  Qin Zhu; Zhiming Wang; Yu Hu; Jindong Li; Xinying Li; Ledu Zhou; Yun Huang
Journal:  Oncol Rep       Date:  2012-02-09       Impact factor: 3.906

4.  Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B.

Authors:  Renate G van der Molen; Dave Sprengers; Rekha S Binda; Esther C de Jong; Hubert G M Niesters; Johannes G Kusters; Jaap Kwekkeboom; Harry L A Janssen
Journal:  Hepatology       Date:  2004-09       Impact factor: 17.425

5.  Hepatitis C virus-linked mitochondrial dysfunction promotes hypoxia-inducible factor 1 alpha-mediated glycolytic adaptation.

Authors:  Maria Ripoli; Annamaria D'Aprile; Giovanni Quarato; Magdalena Sarasin-Filipowicz; Jérôme Gouttenoire; Rosella Scrima; Olga Cela; Domenico Boffoli; Markus H Heim; Darius Moradpour; Nazzareno Capitanio; Claudia Piccoli
Journal:  J Virol       Date:  2010-01       Impact factor: 5.103

6.  Mechanism of the interferon alpha response against hepatitis C virus replicons.

Authors:  Ju-Tao Guo; Ji A Sohn; Qing Zhu; Christoph Seeger
Journal:  Virology       Date:  2004-07-20       Impact factor: 3.616

7.  Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma.

Authors:  Laura Gramantieri; Manuela Ferracin; Francesca Fornari; Angelo Veronese; Silvia Sabbioni; Chang-Gong Liu; George A Calin; Catia Giovannini; Eros Ferrazzi; Gian Luca Grazi; Carlo M Croce; Luigi Bolondi; Massimo Negrini
Journal:  Cancer Res       Date:  2007-07-01       Impact factor: 12.701

8.  -509C>T polymorphism in the TGF-beta1 gene promoter, impact on the hepatocellular carcinoma risk in Chinese patients with chronic hepatitis B virus infection.

Authors:  Peng Qi; Yue-ming Chen; Hao Wang; Meng Fang; Qiang Ji; Yun-peng Zhao; Xiao-juan Sun; Yan Liu; Chun-fang Gao
Journal:  Cancer Immunol Immunother       Date:  2009-01-25       Impact factor: 6.968

9.  Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma.

Authors:  Trevor J Grant; Joshua A Bishop; Lisa M Christadore; Girish Barot; Hang Gyeong Chin; Sarah Woodson; John Kavouris; Ayesha Siddiq; Rachel Gredler; Xue-Ning Shen; Jennifer Sherman; Tracy Meehan; Kevin Fitzgerald; Sriharsa Pradhan; Laura A Briggs; William H Andrews; Devanand Sarkar; Scott E Schaus; Ulla Hansen
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-06       Impact factor: 11.205

10.  Epigenetic repression of E-cadherin expression by hepatitis B virus x antigen in liver cancer.

Authors:  A Arzumanyan; T Friedman; E Kotei; I O L Ng; Z Lian; M A Feitelson
Journal:  Oncogene       Date:  2011-06-27       Impact factor: 9.867
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  318 in total

Review 1.  The emerging role of nuclear viral DNA sensors.

Authors:  Benjamin A Diner; Krystal K Lum; Ileana M Cristea
Journal:  J Biol Chem       Date:  2015-09-09       Impact factor: 5.157

2.  A Viral Exposure Signature Defines Early Onset of Hepatocellular Carcinoma.

Authors:  Jinping Liu; Wei Tang; Anuradha Budhu; Marshonna Forgues; Maria O Hernandez; Julián Candia; Yujin Kim; Elise D Bowman; Stefan Ambs; Yongmei Zhao; Bao Tran; Xiaolin Wu; Christopher Koh; Pallavi Surana; T Jake Liang; Maria Guarnera; Dean Mann; Manoj Rajaure; Tim F Greten; Zhanwei Wang; Herbert Yu; Xin Wei Wang
Journal:  Cell       Date:  2020-06-10       Impact factor: 41.582

3.  Establishment of a Patient-Derived Xenograft Tumor From Hepatitis C-Associated Liver Cancer and Evaluation of Imatinib Treatment Efficacy.

Authors:  Mustafa Nazzal; Subhayan Sur; Robert Steele; Mousumi Khatun; Tapas Patra; Nancy Phillips; John Long; Ranjit Ray; Ratna B Ray
Journal:  Hepatology       Date:  2020-08       Impact factor: 17.425

4.  Dynamic expression of ZNF382 and its tumor-suppressor role in hepatitis B virus-related hepatocellular carcinogenesis.

Authors:  Siwen Dang; Jingshi Zhou; Yijun Chen; Pu Chen; Meiju Ji; Bingyin Shi; Qi Yang; Peng Hou
Journal:  Oncogene       Date:  2019-02-25       Impact factor: 9.867

5.  Outflanking HCV.

Authors:  Zhigang Tian
Journal:  Nat Immunol       Date:  2014-01       Impact factor: 25.606

6.  Response.

Authors:  Vikrant V Sahasrabuddhe; Munira Z Gunja; Barry I Graubard; Britton Trabert; Lauren M Schwartz; Yikyung Park; Albert R Hollenbeck; Neal D Freedman; Katherine A McGlynn
Journal:  J Natl Cancer Inst       Date:  2013-05-01       Impact factor: 13.506

Review 7.  Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation.

Authors:  Zdenko Herceg; Marie-Pierre Lambert; Karin van Veldhoven; Christiana Demetriou; Paolo Vineis; Martyn T Smith; Kurt Straif; Christopher P Wild
Journal:  Carcinogenesis       Date:  2013-06-07       Impact factor: 4.944

Review 8.  Chemopreventive strategies in hepatocellular carcinoma.

Authors:  Siddharth Singh; Preet Paul Singh; Lewis R Roberts; William Sanchez
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2013-08-13       Impact factor: 46.802

9.  IGF-I receptor as an emerging potential molecular-targeted for hepatocellular carcinoma in vitro and in vivo.

Authors:  Min Yao; Li Wang; Junling Yang; Xiaodi Yan; Yin Cai; Dengfu Yao
Journal:  Tumour Biol       Date:  2016-09-13

10.  Combined acoustic radiation force impulse, aminotransferase to platelet ratio index and Forns index assessment for hepatic fibrosis grading in hepatitis B.

Authors:  Chang-Feng Dong; Jia Xiao; Ling-Bo Shan; Han-Ying Li; Yong-Jia Xiong; Gui-Lin Yang; Jing Liu; Si-Min Yao; Sha-Xi Li; Xiao-Hua Le; Jing Yuan; Bo-Ping Zhou; George L Tipoe; Ying-Xia Liu
Journal:  World J Hepatol       Date:  2016-05-18
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