Literature DB >> 1946399

DNA-binding protein RAP1 stimulates meiotic recombination at the HIS4 locus in yeast.

M A White1, M Wierdl, P Detloff, T D Petes.   

Abstract

In the yeast Saccharomyces cerevisiae, as in other eukaryotes, some regions of the genome have a much higher rate of meiotic recombination than others. We show below that the binding of the RAP1 protein to a site upstream of the HIS4 gene is necessary for a high rate of meiotic (but not mitotic) recombination at this locus. A mutation in the RAP1 binding site at HIS4 results in a decrease in recombination; overproduction of RAP1 causes an increase in recombination at HIS4 above wild-type levels.

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Year:  1991        PMID： 1946399      PMCID： PMC52799          DOI： 10.1073/pnas.88.21.9755

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  27 in total

1.  Site Specific Induction of Gene Conversion in SCHIZOSACCHAROMYCES POMBE.

Authors:  H Gutz
Journal:  Genetics       Date:  1971-11       Impact factor: 4.562

2.  GCN4 protein, a positive transcription factor in yeast, binds general control promoters at all 5' TGACTC 3' sequences.

Authors:  K Arndt; G R Fink
Journal:  Proc Natl Acad Sci U S A       Date:  1986-11       Impact factor: 11.205

3.  TUF, the yeast DNA-binding factor specific for UASrpg upstream activating sequences: identification of the protein and its DNA-binding domain.

Authors:  J Huet; A Sentenac
Journal:  Proc Natl Acad Sci U S A       Date:  1987-06       Impact factor: 11.205

4.  Replacement of chromosome segments with altered DNA sequences constructed in vitro.

Authors:  S Scherer; R W Davis
Journal:  Proc Natl Acad Sci U S A       Date:  1979-10       Impact factor: 11.205

5.  Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements.

Authors:  D Shore; K Nasmyth
Journal:  Cell       Date:  1987-12-04       Impact factor: 41.582

6.  The Ade6-M26 Mutation of Schizosaccharomyces Pombe Increases the Frequency of Crossing over.

Authors:  P Schuchert; J Kohli
Journal:  Genetics       Date:  1988-07       Impact factor: 4.562

7.  Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination.

Authors:  E Alani; R Padmore; N Kleckner
Journal:  Cell       Date:  1990-05-04       Impact factor: 41.582

8.  The nucleotide sequence of the HIS4 region of yeast.

Authors:  T F Donahue; P J Farabaugh; G R Fink
Journal:  Gene       Date:  1982-04       Impact factor: 3.688

9.  Multiple global regulators control HIS4 transcription in yeast.

Authors:  K T Arndt; C Styles; G R Fink
Journal:  Science       Date:  1987-08-21       Impact factor: 47.728

10.  DNA sequence analysis of the ade6 gene of Schizosaccharomyces pombe. Wild-type and mutant alleles including the recombination host spot allele ade6-M26.

Authors:  P Szankasi; W D Heyer; P Schuchert; J Kohli
Journal:  J Mol Biol       Date:  1988-12-20       Impact factor: 5.469
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  62 in total

1.  Maximal stimulation of meiotic recombination by a yeast transcription factor requires the transcription activation domain and a DNA-binding domain.

Authors:  D T Kirkpatrick; Q Fan; T D Petes
Journal:  Genetics       Date:  1999-05       Impact factor: 4.562

2.  Global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae.

Authors:  J L Gerton; J DeRisi; R Shroff; M Lichten; P O Brown; T D Petes
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-10       Impact factor: 11.205

3.  A test of the CoHR motif associated with meiotic double-strand breaks in Saccharomyces cerevisiae.

Authors:  Stuart J Haring; Lucas J Lautner; Josep M Comeron; Robert E Malone
Journal:  EMBO Rep       Date:  2004-01       Impact factor: 8.807

4.  High-Resolution Global Analysis of the Influences of Bas1 and Ino4 Transcription Factors on Meiotic DNA Break Distributions in Saccharomyces cerevisiae.

Authors:  Xuan Zhu; Scott Keeney
Journal:  Genetics       Date:  2015-08-05       Impact factor: 4.562

5.  Organization and roles of nucleosomes at mouse meiotic recombination hotspots.

Authors:  Irina V Getun; Zhen K Wu; Philippe R J Bois
Journal:  Nucleus       Date:  2012-05-01       Impact factor: 4.197

6.  Recombination hotspot activity of hypervariable minisatellite DNA requires minisatellite DNA binding proteins.

Authors:  W P Wahls; P D Moore
Journal:  Somat Cell Mol Genet       Date:  1998-01

Review 7.  Meiotic recombination hotspots: shaping the genome and insights into hypervariable minisatellite DNA change.

Authors:  W P Wahls
Journal:  Curr Top Dev Biol       Date:  1998       Impact factor: 4.897

8.  Relationship between transcription and initiation of meiotic recombination: toward chromatin accessibility.

Authors:  A Nicolas
Journal:  Proc Natl Acad Sci U S A       Date:  1998-01-06       Impact factor: 11.205

9.  Transcriptional induction of Ty recombination in yeast.

Authors:  Y Nevo-Caspi; M Kupiec
Journal:  Proc Natl Acad Sci U S A       Date:  1994-12-20       Impact factor: 11.205

10.  A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination.

Authors:  J I Piruat; A Aguilera
Journal:  EMBO J       Date:  1998-08-17       Impact factor: 11.598
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