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Literature DB >> 7049842

The nucleotide sequence of the HIS4 region of yeast.

Abstract

We have determined the nucleotide sequence of the yeast HIS4 gene and its 5' and 3' flanking sequences. The protein chain has a calculated Mr-value of 87 935. Th 5' end of the HIS4 transcript maps at a position 63 bp upstream from the site of initiation of protein synthesis. The 3' end of the HIS4 transcript maps at a position approx. 118 bp after the UAG termination codon. There is no evidence for intervening sequences within the transcription unit. Functional sub-regions within the HIS4 coding frame have been identified by determining the sequence changes for various his4 mutations.

Entities: Gene Species

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Year: 1982 PMID： 7049842 DOI： 10.1016/0378-1119(82)90055-5

Source DB: PubMed Journal: Gene ISSN： 0378-1119 Impact factor: 3.688

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Cited

119 in total

1. Somatic pairing of homologs in budding yeast: existence and modulation.

Authors: S M Burgess; N Kleckner; B M Weiner
Journal: Genes Dev Date: 1999-06-15 Impact factor: 11.361

2. Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae.

Authors: P Detloff; M A White; T D Petes
Journal: Genetics Date: 1992-09 Impact factor: 4.562

3. A GCN4 protein recognition element is not sufficient for GCN4-dependent regulation of transcription in the ARO7 promoter of Saccharomyces cerevisiae.

Authors: T Schmidheini; H U Mösch; R Graf; G H Braus
Journal: Mol Gen Genet Date: 1990-10

8. The Pichia pastoris HIS4 gene: nucleotide sequence, creation of a non-reverting his4 deletion mutant, and development of HIS4-based replicating and integrating plasmids.

Authors: D I Crane; S J Gould
Journal: Curr Genet Date: 1994 Nov-Dec Impact factor: 3.886

9. A gene with specific and global effects on recombination of sequences from tandemly repeated genes in Saccharomyces cerevisiae.

Authors: R L Keil; A D McWilliams
Journal: Genetics Date: 1993-11 Impact factor: 4.562

10. GCN1, a translational activator of GCN4 in Saccharomyces cerevisiae, is required for phosphorylation of eukaryotic translation initiation factor 2 by protein kinase GCN2.

Authors: M J Marton; D Crouch; A G Hinnebusch
Journal: Mol Cell Biol Date: 1993-06 Impact factor: 4.272

The nucleotide sequence of the HIS4 region of yeast.

1. Somatic pairing of homologs in budding yeast: existence and modulation.

2. Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae.

3. A GCN4 protein recognition element is not sufficient for GCN4-dependent regulation of transcription in the ARO7 promoter of Saccharomyces cerevisiae.

4. Gene conversion tracts stimulated by HOT1-promoted transcription are long and continuous.

5. Histidine biosynthesis.

6. The pentafunctional arom enzyme of Saccharomyces cerevisiae is a mosaic of monofunctional domains.

7. Structural and functional conservation of histidinol dehydrogenase between plants and microbes.

8. The Pichia pastoris HIS4 gene: nucleotide sequence, creation of a non-reverting his4 deletion mutant, and development of HIS4-based replicating and integrating plasmids.

9. A gene with specific and global effects on recombination of sequences from tandemly repeated genes in Saccharomyces cerevisiae.

10. GCN1, a translational activator of GCN4 in Saccharomyces cerevisiae, is required for phosphorylation of eukaryotic translation initiation factor 2 by protein kinase GCN2.