Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 1H NMR of 5'CGCGTATATACGCG3', a duplex and a four-membered loop.

Literature DB >> 1945888

1H NMR of 5'CGCGTATATACGCG3', a duplex and a four-membered loop.

Abstract

The deoxyribonucleotide 5'CGCGTATATACGCG3' was synthesized and studied by NMR methods. This short, fully palindromic duplex also forms a hairpin under certain conditions described within. As such, it is considered to be a model for cruciform formation. We show that this sequence forms a four-membered loop and a duplex in solution. The duplex is shown to be a normal, B-DNA like helix, while the hairpin is shown to be a four-membered ATAT loop.

Mesh：

Substances：

Year: 1991 PMID： 1945888 PMCID： PMC329064 DOI： 10.1093/nar/19.21.6041

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

19 in total

1. Cruciform structures in supercoiled DNA.

Authors: N Panayotatos; R D Wells
Journal: Nature Date: 1981-02-05 Impact factor: 49.962

2. Nuclear Overhauser effect study and assignment of D stem and reverse-Hoogsteen base pair proton resonances in yeast tRNAAsp.

Authors: S Roy; A G Redfield
Journal: Nucleic Acids Res Date: 1981-12-21 Impact factor: 16.971

3. Hairpin-loop formation by inverted repeats in supercoiled DNA is a local and transmissible property.

Authors: D M Lilley
Journal: Nucleic Acids Res Date: 1981-03-25 Impact factor: 16.971

4. Cruciform transitions in DNA.

Authors: R R Sinden; D E Pettijohn
Journal: J Biol Chem Date: 1984-05-25 Impact factor: 5.157

5. Assignment of the non-exchangeable proton resonances of d(C-G-C-G-A-A-T-T-C-G-C-G) using two-dimensional nuclear magnetic resonance methods.

Authors: D R Hare; D E Wemmer; S H Chou; G Drobny; B R Reid
Journal: J Mol Biol Date: 1983-12-15 Impact factor: 5.469

6. Sequential resonance assignments in 1H NMR spectra of oligonucleotides by two-dimensional NMR spectroscopy.

Authors: R M Scheek; R Boelens; N Russo; J H van Boom; R Kaptein
Journal: Biochemistry Date: 1984-03-27 Impact factor: 3.162

7. Mechanics of sequence-dependent stacking of bases in B-DNA.

Authors: C R Calladine
Journal: J Mol Biol Date: 1982-10-25 Impact factor: 5.469

8. NMR studies of DNA conformation and dynamics in solution.

Authors: D J Patel; S A Kozlowski; S Ikuta; K Itakura; R Bhatt; D R Hare
Journal: Cold Spring Harb Symp Quant Biol Date: 1983

9. High-resolution phosphorus nuclear magnetic resonance spectra of yeast phenylalanine transfer ribonucleic acid. Melting curves and relaxation effects.

Authors: D G Gorenstein; B A Luxon
Journal: Biochemistry Date: 1979-08-21 Impact factor: 3.162

6. The effects of nucleotide sequence changes on DNA secondary structure formation in Escherichia coli are consistent with cruciform extrusion in vivo.

Authors: A Davison; D R Leach
Journal: Genetics Date: 1994-06 Impact factor: 4.562

6 in total

1H NMR of 5'CGCGTATATACGCG3', a duplex and a four-membered loop.

1. Cruciform structures in supercoiled DNA.

2. Nuclear Overhauser effect study and assignment of D stem and reverse-Hoogsteen base pair proton resonances in yeast tRNAAsp.

3. Hairpin-loop formation by inverted repeats in supercoiled DNA is a local and transmissible property.

4. Cruciform transitions in DNA.

5. Assignment of the non-exchangeable proton resonances of d(C-G-C-G-A-A-T-T-C-G-C-G) using two-dimensional nuclear magnetic resonance methods.

6. Sequential resonance assignments in 1H NMR spectra of oligonucleotides by two-dimensional NMR spectroscopy.

7. Mechanics of sequence-dependent stacking of bases in B-DNA.

8. NMR studies of DNA conformation and dynamics in solution.

9. High-resolution phosphorus nuclear magnetic resonance spectra of yeast phenylalanine transfer ribonucleic acid. Melting curves and relaxation effects.

Review 10. Structure, kinetics and thermodynamics of DNA hairpin fragments in solution.

1. Hairpin opening by single-strand-specific nucleases.

2. Methylation of the nucleobases in RNA oligonucleotides mediates duplex-hairpin conversion.

3. Hairpins in a DNA site for topoisomerase II studied by 1H- and 31P-NMR.

4. A comparison of the hairpin stability of the palindromic d(CGCG(A/T)4CGCG) oligonucleotides.

5. Conformation of the circular dumbbell d<pCGC-TT-GCG-TT>: structure determination and molecular dynamics.

6. The effects of nucleotide sequence changes on DNA secondary structure formation in Escherichia coli are consistent with cruciform extrusion in vivo.