Literature DB >> 19444846

Taking fingerprints of DNA polymerases: multiplex enzyme profiling on DNA arrays.

Ramon Kranaster1, Andreas Marx.   

Abstract

A novel screening approach based on an oligonucleotide-addressing enzyme assay enables multiplexed simultaneous profiling of DNA polymerases in nanoliter volumes in terms of their different properties. This approach was used to identify enzymes with altered properties out of a library of protein mutants.

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Year:  2009        PMID： 19444846     DOI： 10.1002/anie.200900953

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  5 in total

1.  Directed evolution of DNA polymerases for next-generation sequencing.

Authors:  Aaron M Leconte; Maha P Patel; Lauryn E Sass; Peter McInerney; Mirna Jarosz; Li Kung; Jayson L Bowers; Philip R Buzby; J William Efcavitch; Floyd E Romesberg
Journal:  Angew Chem Int Ed Engl       Date:  2010-08-09       Impact factor: 15.336

2.  Boronic acid functionalized peptidyl synthetic lectins: combinatorial library design, peptide sequencing, and selective glycoprotein recognition.

Authors:  Kevin L Bicker; Jing Sun; John J Lavigne; Paul R Thompson
Journal:  ACS Comb Sci       Date:  2011-03-25       Impact factor: 3.784

Review 3.  Directed polymerase evolution.

Authors:  Tingjian Chen; Floyd E Romesberg
Journal:  FEBS Lett       Date:  2013-11-05       Impact factor: 4.124

Review 4.  Exploring the Chemistry of Genetic Information Storage and Propagation through Polymerase Engineering.

Authors:  Gillian Houlihan; Sebastian Arangundy-Franklin; Philipp Holliger
Journal:  Acc Chem Res       Date:  2017-04-06       Impact factor: 22.384

5.  Variants of a Thermus aquaticus DNA polymerase with increased selectivity for applications in allele- and methylation-specific amplification.

Authors:  Matthias Drum; Ramon Kranaster; Christina Ewald; Rainer Blasczyk; Andreas Marx
Journal:  PLoS One       Date:  2014-05-06       Impact factor: 3.240
  5 in total

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