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Literature DB >> 19419860

Synthesis and structure-activity relationships of bengazole A analogs.

Roger J Mulder¹, Cynthia M Shafer, Doralyn S Dalisay, Tadeusz F Molinski.

Abstract

Analogs of the potent antifungal agent, bengazole A, were prepared and evaluated against Candida spp. in both microbroth dilution and disk diffusion assays.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2009 PMID： 19419860 PMCID： PMC2691865 DOI： 10.1016/j.bmcl.2009.04.069

Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823

9 in total

1. First Total Synthesis of Bengazole A.

Authors: Roger J. Mulder; Cynthia M. Shafer; Tadeusz F. Molinski
Journal: J Org Chem Date: 1999-06-25 Impact factor: 4.354

2. Differential modulation of the antifungal activity of amphotericin B by natural and ent-cholesterol.

Authors: Rowena K Richter; Daniel E Mickus; Scott D Rychnovsky; Tadeusz F Molinski
Journal: Bioorg Med Chem Lett Date: 2004-01-05 Impact factor: 2.823

3. Stereocontrolled total synthesis of bengazole a: a marine bisoxazole natural product displaying potent antifungal properties.

Authors: James A Bull; Emily P Balskus; Richard A J Horan; Martin Langner; Steven V Ley
Journal: Angew Chem Int Ed Engl Date: 2006-10-13 Impact factor: 15.336

4. Bengazoles C-G from the Sponge Jaspis sp. Synthesis of the Side Chain and Determination of Absolute Configuration.

Authors: Philip A. Searle; Rowena K. Richter; Tadeusz F. Molinski
Journal: J Org Chem Date: 1996-06-14 Impact factor: 4.354

5. Monosubstituted Oxazoles. 1. Synthesis of 5-Substituted Oxazoles by Directed Alkylation.

Authors: Cynthia M. Shafer; Tadeusz F. Molinski
Journal: J Org Chem Date: 1998-02-06 Impact factor: 4.354

Review 6. Developments in marine natural products. Receptor-specific bioactive compounds.

Authors: T F Molinski
Journal: J Nat Prod Date: 1993-01 Impact factor: 4.050

7. Amino acid derivatives from the marine sponge Jaspis digonoxea.

Authors: A Rudi; Y Kashman; Y Benayahu; M Schleyer
Journal: J Nat Prod Date: 1994-06 Impact factor: 4.050

8. Total synthesis of potent antifungal marine bisoxazole natural products bengazoles A and B.

Authors: James A Bull; Emily P Balskus; Richard A J Horan; Martin Langner; Steven V Ley
Journal: Chemistry Date: 2007 Impact factor: 5.236

9. New structures and bioactivity patterns of bengazole alkaloids from a choristid marine sponge.

Authors: J Rodríguez; R M Nieto; P Crews
Journal: J Nat Prod Date: 1993-12 Impact factor: 4.050

9 in total

7 in total

1. Synthesis and chain-dependent antifungal activity of long-chain 2H-azirine-carboxylate esters related to dysidazirine.

Authors: Colin K Skepper; Doralyn S Dalisay; Tadeusz F Molinski
Journal: Bioorg Med Chem Lett Date: 2010-02-01 Impact factor: 2.823

2. Phorboxazole Synthetic Studies: Design, Synthesis and Biological Evaluation of Phorboxazole A and Hemi-Phorboxazole A Related Analogues.

Authors: Amos B Smith; Anne-Marie L Hogan; Zhuqing Liu; Thomas M Razler; Regina M Meis; Brandon I Morinaka; Tadeusz F Molinski
Journal: Tetrahedron Date: 2011-07-08 Impact factor: 2.457

Review 3. The Development of the Bengamides as New Antibiotics against Drug-Resistant Bacteria.

Authors: Cristina Porras-Alcalá; Federico Moya-Utrera; Miguel García-Castro; Antonio Sánchez-Ruiz; Juan Manuel López-Romero; María Soledad Pino-González; Amelia Díaz-Morilla; Seiya Kitamura; Dennis W Wolan; José Prados; Consolación Melguizo; Iván Cheng-Sánchez; Francisco Sarabia
Journal: Mar Drugs Date: 2022-05-31 Impact factor: 6.085