Literature DB >> 14684310

Differential modulation of the antifungal activity of amphotericin B by natural and ent-cholesterol.

Rowena K Richter1, Daniel E Mickus, Scott D Rychnovsky, Tadeusz F Molinski.   

Abstract

The addition of exogenous ent-cholesterol suppressed the antifungal activity of the amphotericin B when added to cultures of Candida albicans, but to a lesser extent than natural cholesterol. There were no detectable differences between added 2a or 2b on the antifungal activities of jaspamide or bengazole A, two unrelated antifungal natural products.

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Year:  2004        PMID: 14684310     DOI: 10.1016/j.bmcl.2003.10.018

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  6 in total

1.  Stereospecific requirement of cholesterol in the function of the serotonin1A receptor.

Authors:  Md Jafurulla; Bhagyashree D Rao; Sugunan Sreedevi; Jean-Marie Ruysschaert; Douglas F Covey; Amitabha Chattopadhyay
Journal:  Biochim Biophys Acta       Date:  2013-09-02

2.  Role of chirality in peptide-induced formation of cholesterol-rich domains.

Authors:  Richard M Epand; Scott D Rychnovsky; Jitendra D Belani; Raquel F Epand
Journal:  Biochem J       Date:  2005-09-01       Impact factor: 3.857

Review 3.  The enantiomer of cholesterol.

Authors:  E J Westover; D F Covey
Journal:  J Membr Biol       Date:  2004-11       Impact factor: 1.843

4.  Characterization of enantiomeric bile acid-induced apoptosis in colon cancer cell lines.

Authors:  Bryson W Katona; Shrikant Anant; Douglas F Covey; William F Stenson
Journal:  J Biol Chem       Date:  2008-12-03       Impact factor: 5.157

Review 5.  ent-Steroids: novel tools for studies of signaling pathways.

Authors:  Douglas F Covey
Journal:  Steroids       Date:  2008-12-03       Impact factor: 2.668

6.  Synthesis and structure-activity relationships of bengazole A analogs.

Authors:  Roger J Mulder; Cynthia M Shafer; Doralyn S Dalisay; Tadeusz F Molinski
Journal:  Bioorg Med Chem Lett       Date:  2009-04-22       Impact factor: 2.823

  6 in total

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