Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Advances in histamine pharmacology reveal new drug targets.

Literature DB >> 19413566

Advances in histamine pharmacology reveal new drug targets.

Abstract

This Themed Issue consists of three reviews and 11 original articles authored by internationally respected industrial and academic pharmacologists from across three continents. It derives from the highly successful symposium on 'The H3 and H4 histamine receptors: the antihistamines for the 21(st) century', which took place at EPHAR 2008 in Manchester University, and encompasses new roles, new compounds and exciting new therapeutic areas for histamine.

Entities: Chemical

Mesh：

Substances：

Year: 2009 PMID： 19413566 PMCID： PMC2697794 DOI： 10.1111/j.1476-5381.2009.00228.x

Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739

14 in total

1. Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors.

Authors: Carla Ferrada; Estefanía Moreno; Vicent Casadó; Gerold Bongers; Antoni Cortés; Josefa Mallol; Enric I Canela; Rob Leurs; Sergi Ferré; Carme Lluís; Rafael Franco
Journal: Br J Pharmacol Date: 2009-05 Impact factor: 8.739

Review 2. Structural features of mammalian histidine decarboxylase reveal the basis for specific inhibition.

Authors: A A Moya-García; A Pino-Angeles; R Gil-Redondo; A Morreale; F Sánchez-Jiménez
Journal: Br J Pharmacol Date: 2009-05 Impact factor: 8.739

Review 3. Molecular and biochemical pharmacology of the histamine H4 receptor.

Authors: Rob Leurs; Paul L Chazot; Fiona C Shenton; Herman D Lim; Iwan J P de Esch
Journal: Br J Pharmacol Date: 2009-05 Impact factor: 8.739

Review 4. The role of histamine H4 receptor in immune and inflammatory disorders.

Authors: E Zampeli; E Tiligada
Journal: Br J Pharmacol Date: 2009-03-20 Impact factor: 8.739

5. Altered histamine H3 receptor radioligand binding in post-mortem brain samples from subjects with psychiatric diseases.

Authors: C Y Jin; O Anichtchik; P Panula
Journal: Br J Pharmacol Date: 2009-05 Impact factor: 8.739

6. The histamine H4 receptor is functionally expressed on neurons in the mammalian CNS.

Authors: W M Connelly; F C Shenton; N Lethbridge; R Leurs; H J Waldvogel; R L M Faull; G Lees; P L Chazot
Journal: Br J Pharmacol Date: 2009-05 Impact factor: 8.739

7. Pharmacological characterization of the new histamine H4 receptor agonist VUF 8430.

Authors: Herman D Lim; Maristella Adami; Elena Guaita; Thomas Werfel; Rogier A Smits; Iwan J P de Esch; Remko A Bakker; Ralf Gutzmer; Gabriella Coruzzi; Rob Leurs
Journal: Br J Pharmacol Date: 2009-05 Impact factor: 8.739

8. In vitro and in vivo characterization of A-940894: a potent histamine H4 receptor antagonist with anti-inflammatory properties.

Authors: M I Strakhova; C A Cuff; A M Manelli; T L Carr; D G Witte; J L Baranowski; T A Vortherms; T R Miller; L Rundell; M J McPherson; R M Adair; A A Brito; B M Bettencourt; B B Yao; J M Wetter; K C Marsh; H Liu; M D Cowart; J D Brioni; T A Esbenshade
Journal: Br J Pharmacol Date: 2009-05 Impact factor: 8.739

9. Effects of L-histidine depletion and L-tyrosine/L-phenylalanine depletion on sensory and motor processes in healthy volunteers.

Authors: P van Ruitenbeek; A Sambeth; A Vermeeren; S N Young; W J Riedel
Journal: Br J Pharmacol Date: 2009-05 Impact factor: 8.739

10. Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep-wake cycle and narcoleptic episodes in Ox-/- mice.

Authors: R X Guo; C Anaclet; J C Roberts; R Parmentier; M Zhang; G Guidon; C Buda; J P Sastre; J Q Feng; P Franco; S H Brown; N Upton; A D Medhurst; J S Lin
Journal: Br J Pharmacol Date: 2009-05 Impact factor: 8.739

3 in total