Literature DB >> 19369936

Clinically available pharmacogenomics tests.

D A Flockhart1, T Skaar, D S Berlin, T E Klein, A T Nguyen.   

Abstract

The development of robust and clinically valuable pharmacogenomic tests has been anticipated to be one of the first tangible results of the Human Genome Project. Despite both obvious and unanticipated obstacles, a number of tests have now become available in various practice settings. Lessons can be learned from examination of these tests, the evidence that has catalyzed their use, their value to prescribers, and their merit as tools for personalizing therapeutics.

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Year:  2009        PMID: 19369936      PMCID: PMC2730436          DOI: 10.1038/clpt.2009.39

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN: 0009-9236            Impact factor:   6.875


  31 in total

1.  Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin.

Authors:  Ji-Youn Han; Hyeong-Seok Lim; Eun Soon Shin; Yeon-Kyeong Yoo; Yong Hoon Park; Jong-Eun Lee; In-Jin Jang; Dae Ho Lee; Jin Soo Lee
Journal:  J Clin Oncol       Date:  2006-04-24       Impact factor: 44.544

2.  Women experience greater toxicity with fluorouracil-based chemotherapy for colorectal cancer.

Authors:  Jeff A Sloan; Richard M Goldberg; Daniel J Sargent; Delfino Vargas-Chanes; Suresh Nair; Steven S Cha; Paul J Novotny; Michael A Poon; Michael J O'Connell; Charles L Loprinzi
Journal:  J Clin Oncol       Date:  2002-03-15       Impact factor: 44.544

3.  An association between clozapine-induced agranulocytosis in schizophrenics and HLA-DQB1*0201.

Authors:  Avraham Amar; Ronnen H. Segman; Shlomo Shtrussberg; Leny Sherman; Cilly Safirman; Bernard Lerer; Chaim Brautbar
Journal:  Int J Neuropsychopharmacol       Date:  1998-07       Impact factor: 5.176

4.  Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

Authors:  Ewan Birney; John A Stamatoyannopoulos; Anindya Dutta; Roderic Guigó; Thomas R Gingeras; Elliott H Margulies; Zhiping Weng; Michael Snyder; Emmanouil T Dermitzakis; Robert E Thurman; Michael S Kuehn; Christopher M Taylor; Shane Neph; Christoph M Koch; Saurabh Asthana; Ankit Malhotra; Ivan Adzhubei; Jason A Greenbaum; Robert M Andrews; Paul Flicek; Patrick J Boyle; Hua Cao; Nigel P Carter; Gayle K Clelland; Sean Davis; Nathan Day; Pawandeep Dhami; Shane C Dillon; Michael O Dorschner; Heike Fiegler; Paul G Giresi; Jeff Goldy; Michael Hawrylycz; Andrew Haydock; Richard Humbert; Keith D James; Brett E Johnson; Ericka M Johnson; Tristan T Frum; Elizabeth R Rosenzweig; Neerja Karnani; Kirsten Lee; Gregory C Lefebvre; Patrick A Navas; Fidencio Neri; Stephen C J Parker; Peter J Sabo; Richard Sandstrom; Anthony Shafer; David Vetrie; Molly Weaver; Sarah Wilcox; Man Yu; Francis S Collins; Job Dekker; Jason D Lieb; Thomas D Tullius; Gregory E Crawford; Shamil Sunyaev; William S Noble; Ian Dunham; France Denoeud; Alexandre Reymond; Philipp Kapranov; Joel Rozowsky; Deyou Zheng; Robert Castelo; Adam Frankish; Jennifer Harrow; Srinka Ghosh; Albin Sandelin; Ivo L Hofacker; Robert Baertsch; Damian Keefe; Sujit Dike; Jill Cheng; Heather A Hirsch; Edward A Sekinger; Julien Lagarde; Josep F Abril; Atif Shahab; Christoph Flamm; Claudia Fried; Jörg Hackermüller; Jana Hertel; Manja Lindemeyer; Kristin Missal; Andrea Tanzer; Stefan Washietl; Jan Korbel; Olof Emanuelsson; Jakob S Pedersen; Nancy Holroyd; Ruth Taylor; David Swarbreck; Nicholas Matthews; Mark C Dickson; Daryl J Thomas; Matthew T Weirauch; James Gilbert; Jorg Drenkow; Ian Bell; XiaoDong Zhao; K G Srinivasan; Wing-Kin Sung; Hong Sain Ooi; Kuo Ping Chiu; Sylvain Foissac; Tyler Alioto; Michael Brent; Lior Pachter; Michael L Tress; Alfonso Valencia; Siew Woh Choo; Chiou Yu Choo; Catherine Ucla; Caroline Manzano; Carine Wyss; Evelyn Cheung; Taane G Clark; James B Brown; Madhavan Ganesh; Sandeep Patel; Hari Tammana; Jacqueline Chrast; Charlotte N Henrichsen; Chikatoshi Kai; Jun Kawai; Ugrappa Nagalakshmi; Jiaqian Wu; Zheng Lian; Jin Lian; Peter Newburger; Xueqing Zhang; Peter Bickel; John S Mattick; Piero Carninci; Yoshihide Hayashizaki; Sherman Weissman; Tim Hubbard; Richard M Myers; Jane Rogers; Peter F Stadler; Todd M Lowe; Chia-Lin Wei; Yijun Ruan; Kevin Struhl; Mark Gerstein; Stylianos E Antonarakis; Yutao Fu; Eric D Green; Ulaş Karaöz; Adam Siepel; James Taylor; Laura A Liefer; Kris A Wetterstrand; Peter J Good; Elise A Feingold; Mark S Guyer; Gregory M Cooper; George Asimenos; Colin N Dewey; Minmei Hou; Sergey Nikolaev; Juan I Montoya-Burgos; Ari Löytynoja; Simon Whelan; Fabio Pardi; Tim Massingham; Haiyan Huang; Nancy R Zhang; Ian Holmes; James C Mullikin; Abel Ureta-Vidal; Benedict Paten; Michael Seringhaus; Deanna Church; Kate Rosenbloom; W James Kent; Eric A Stone; Serafim Batzoglou; Nick Goldman; Ross C Hardison; David Haussler; Webb Miller; Arend Sidow; Nathan D Trinklein; Zhengdong D Zhang; Leah Barrera; Rhona Stuart; David C King; Adam Ameur; Stefan Enroth; Mark C Bieda; Jonghwan Kim; Akshay A Bhinge; Nan Jiang; Jun Liu; Fei Yao; Vinsensius B Vega; Charlie W H Lee; Patrick Ng; Atif Shahab; Annie Yang; Zarmik Moqtaderi; Zhou Zhu; Xiaoqin Xu; Sharon Squazzo; Matthew J Oberley; David Inman; Michael A Singer; Todd A Richmond; Kyle J Munn; Alvaro Rada-Iglesias; Ola Wallerman; Jan Komorowski; Joanna C Fowler; Phillippe Couttet; Alexander W Bruce; Oliver M Dovey; Peter D Ellis; Cordelia F Langford; David A Nix; Ghia Euskirchen; Stephen Hartman; Alexander E Urban; Peter Kraus; Sara Van Calcar; Nate Heintzman; Tae Hoon Kim; Kun Wang; Chunxu Qu; Gary Hon; Rosa Luna; Christopher K Glass; M Geoff Rosenfeld; Shelley Force Aldred; Sara J Cooper; Anason Halees; Jane M Lin; Hennady P Shulha; Xiaoling Zhang; Mousheng Xu; Jaafar N S Haidar; Yong Yu; Yijun Ruan; Vishwanath R Iyer; Roland D Green; Claes Wadelius; Peggy J Farnham; Bing Ren; Rachel A Harte; Angie S Hinrichs; Heather Trumbower; Hiram Clawson; Jennifer Hillman-Jackson; Ann S Zweig; Kayla Smith; Archana Thakkapallayil; Galt Barber; Robert M Kuhn; Donna Karolchik; Lluis Armengol; Christine P Bird; Paul I W de Bakker; Andrew D Kern; Nuria Lopez-Bigas; Joel D Martin; Barbara E Stranger; Abigail Woodroffe; Eugene Davydov; Antigone Dimas; Eduardo Eyras; Ingileif B Hallgrímsdóttir; Julian Huppert; Michael C Zody; Gonçalo R Abecasis; Xavier Estivill; Gerard G Bouffard; Xiaobin Guan; Nancy F Hansen; Jacquelyn R Idol; Valerie V B Maduro; Baishali Maskeri; Jennifer C McDowell; Morgan Park; Pamela J Thomas; Alice C Young; Robert W Blakesley; Donna M Muzny; Erica Sodergren; David A Wheeler; Kim C Worley; Huaiyang Jiang; George M Weinstock; Richard A Gibbs; Tina Graves; Robert Fulton; Elaine R Mardis; Richard K Wilson; Michele Clamp; James Cuff; Sante Gnerre; David B Jaffe; Jean L Chang; Kerstin Lindblad-Toh; Eric S Lander; Maxim Koriabine; Mikhail Nefedov; Kazutoyo Osoegawa; Yuko Yoshinaga; Baoli Zhu; Pieter J de Jong
Journal:  Nature       Date:  2007-06-14       Impact factor: 49.962

5.  Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine.

Authors:  Vered Stearns; Michael D Johnson; James M Rae; Alan Morocho; Antonella Novielli; Pankaj Bhargava; Daniel F Hayes; Zeruesenay Desta; David A Flockhart
Journal:  J Natl Cancer Inst       Date:  2003-12-03       Impact factor: 13.506

6.  Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group.

Authors:  Matthias Schwab; Ulrich M Zanger; Claudia Marx; Elke Schaeffeler; Kathrin Klein; Jürgen Dippon; Reinhold Kerb; Julia Blievernicht; Joachim Fischer; Ute Hofmann; Carsten Bokemeyer; Michel Eichelbaum
Journal:  J Clin Oncol       Date:  2008-02-25       Impact factor: 44.544

7.  High sensitivity of human leukocyte antigen-b*5701 as a marker for immunologically confirmed abacavir hypersensitivity in white and black patients.

Authors:  Michael Saag; Rukmini Balu; Elizabeth Phillips; Philip Brachman; Claudia Martorell; William Burman; Britt Stancil; Michael Mosteller; Cindy Brothers; Paul Wannamaker; Arlene Hughes; Denise Sutherland-Phillips; Simon Mallal; Mark Shaefer
Journal:  Clin Infect Dis       Date:  2008-04-01       Impact factor: 9.079

8.  Relative importance of dose, body surface area, sex, and age for 5-fluorouracil clearance.

Authors:  R E Port; B Daniel; R W Ding; R Herrmann
Journal:  Oncology       Date:  1991       Impact factor: 2.935

9.  Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism.

Authors:  L Lennard; J A Van Loon; R M Weinshilboum
Journal:  Clin Pharmacol Ther       Date:  1989-08       Impact factor: 6.875

10.  Pharmacogenetic testing of CYP2C9 and VKORC1 alleles for warfarin.

Authors:  David A Flockhart; Dennis O'Kane; Marc S Williams; Michael S Watson; David A Flockhart; Brian Gage; Roy Gandolfi; Richard King; Elaine Lyon; Robert Nussbaum; Dennis O'Kane; Kevin Schulman; David Veenstra; Marc S Williams; Michael S Watson
Journal:  Genet Med       Date:  2008-02       Impact factor: 8.822

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  21 in total

1.  Genetic self knowledge and the future of epidemiologic confounding.

Authors:  Tyler J VanderWeele; Tyler Vander Weele
Journal:  Am J Hum Genet       Date:  2010-08-13       Impact factor: 11.025

2.  Experimental therapeutics: a paradigm for personalized medicine.

Authors:  Scott A Waldman; Walter K Kraft; Timothy J Nelson; Andre Terzic
Journal:  Clin Transl Sci       Date:  2009-12       Impact factor: 4.689

3.  Survey of genetic counselors and clinical geneticists' use and attitudes toward pharmacogenetic testing.

Authors:  S B Haga; J M O'Daniel; G M Tindall; R Mills; I M Lipkus; R Agans
Journal:  Clin Genet       Date:  2012-02-19       Impact factor: 4.438

Review 4.  Concept of pharmacogenomics and future considerations.

Authors:  Harpreet Kaur; Sandeep Grover; Ritushree Kukreti
Journal:  CNS Neurosci Ther       Date:  2013-08-07       Impact factor: 5.243

Review 5.  Personalized genomic information: preparing for the future of genetic medicine.

Authors:  Alan E Guttmacher; Amy L McGuire; Bruce Ponder; Kári Stefánsson
Journal:  Nat Rev Genet       Date:  2010-01-12       Impact factor: 53.242

6.  Challenges of incorporating pharmacogenomics into clinical practice.

Authors:  Sharon Marsh; Tibor van Rooij
Journal:  Gastrointest Cancer Res       Date:  2009-09

7.  Bionic technologies transforming the science of healthcare delivery.

Authors:  Scott A Waldman; Andre Terzic
Journal:  Clin Transl Sci       Date:  2011-04       Impact factor: 4.689

8.  Exploring Variation in Known Pharmacogenetic Variants and its Association with Drug Response in Different Mexican Populations.

Authors:  Vanessa Gonzalez-Covarrubias; José Jaime Martínez-Magaña; Regina Coronado-Sosa; Beatriz Villegas-Torres; Alma D Genis-Mendoza; Pablo Canales-Herrerias; Humberto Nicolini; Xavier Soberón
Journal:  Pharm Res       Date:  2016-07-07       Impact factor: 4.200

Review 9.  Pharmacogenomics in the clinic.

Authors:  Mary V Relling; William E Evans
Journal:  Nature       Date:  2015-10-15       Impact factor: 49.962

Review 10.  The Emerging Potential for Network Analysis to Inform Precision Cancer Medicine.

Authors:  Kivilcim Ozturk; Michelle Dow; Daniel E Carlin; Rafael Bejar; Hannah Carter
Journal:  J Mol Biol       Date:  2018-06-15       Impact factor: 5.469

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