Literature DB >> 19362245

Secondary neutron doses for several beam configurations for proton therapy.

Dongho Shin1, Myonggeun Yoon, Jungwon Kwak, Jungwook Shin, Se Byeong Lee, Sung Yong Park, Soah Park, Dae Yong Kim, Kwan Ho Cho.   

Abstract

PURPOSE: To compare possible neutron doses produced in scanning and scattering modes, with the latter assessed using a newly built passive-scattering proton beam line. METHODS AND MATERIALS: A 40 x 30.5 x 30-cm water phantom was irradiated with 230-MeV proton beams using a gantry angle of 270 degrees , a 10-cm-diameter snout, and a brass aperture with a diameter of 7 cm and a thickness of 6.5 cm. The secondary neutron doses during irradiation were measured at various points using CR-39 detectors, and these measurements were cross-checked using a neutron survey meter with a 22-cm range and a 5-cm spread-out Bragg peak.
RESULTS: The maximum doses due to secondary neutrons produced by a scattering beam-delivery system were on the order of 0.152 mSv/Gy and 1.17 mSv/Gy at 50 cm from the beam isocenter in the longitudinal (0 degrees ) and perpendicular (90 degrees ) directions, respectively. The neutron dose equivalent to the proton absorbed dose, measured from 10 cm to 100 cm from the isocenter, ranged from 0.071 mSv/Gy to 1.96 mSv/Gy in the direction of the beam line (i.e., phi = 0 degrees ). The largest neutron dose, of 3.88 mSv/Gy, was observed at 135 degrees and 25 cm from the isocenter.
CONCLUSIONS: Although the secondary neutron doses in proton therapy were higher when a scattering mode rather than a scanning mode was used, they did not exceed the scattered photon dose in typical photon treatments.

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Year:  2009        PMID: 19362245     DOI: 10.1016/j.ijrobp.2008.10.090

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  8 in total

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Authors:  Rui Zhang; Angélica Pérez-Andújar; Jonas D Fontenot; Phillip J Taddei; Wayne D Newhauser
Journal:  Phys Med Biol       Date:  2010-11-12       Impact factor: 3.609

2.  The determination of a dose deposited in reference medium due to (p,n) reaction occurring during proton therapy.

Authors:  Anna Dawidowska; Monika Paluch Ferszt; Adam Konefał
Journal:  Rep Pract Oncol Radiother       Date:  2014-05-05

3.  Secondary neutron spectrum from 250-MeV passively scattered proton therapy: measurement with an extended-range Bonner sphere system.

Authors:  Rebecca M Howell; E A Burgett
Journal:  Med Phys       Date:  2014-09       Impact factor: 4.071

4.  Reduction of the secondary neutron dose in passively scattered proton radiotherapy, using an optimized pre-collimator/collimator.

Authors:  David J Brenner; Carl D Elliston; Eric J Hall; Harald Paganetti
Journal:  Phys Med Biol       Date:  2009-09-24       Impact factor: 3.609

5.  Hypofractionated passively scattered proton radiotherapy for low- and intermediate-risk prostate cancer is not associated with post-treatment testosterone suppression.

Authors:  Whoon Jong Kil; Romaine C Nichols; Bradford S Hoppe; Christopher G Morris; Robert B Marcus; William Mendenhall; Nancy P Mendenhall; Zuofeng Li; Joseph A Costa; Christopher R Williams; Randal H Henderson
Journal:  Acta Oncol       Date:  2013-04       Impact factor: 4.089

6.  Radiotherapy-induced malignancies: review of clinical features, pathobiology, and evolving approaches for mitigating risk.

Authors:  Steve Braunstein; Jean L Nakamura
Journal:  Front Oncol       Date:  2013-04-03       Impact factor: 6.244

7.  Secondary neutron dose measurement for proton eye treatment using an eye snout with a borated neutron absorber.

Authors:  Dong Wook Kim; Weon Kuu Chung; Jungwook Shin; Young Kyung Lim; Dongho Shin; Se Byeong Lee; Myongguen Yoon; Sung-Yong Park; Dong Oh Shin; Jung Keun Cho
Journal:  Radiat Oncol       Date:  2013-07-17       Impact factor: 3.481

8.  Serum testosterone changes in patients treated with radiation therapy alone for prostate cancer on NRG oncology RTOG 9408.

Authors:  R Charles Nichols; Chen Hu; Jean-Paul Bahary; Kenneth L Zeitzer; Luis Souhami; Mark H Leibenhaut; Marvin Rotman; Elizabeth M Gore; Alexander G Balogh; David McGowan; Jeff Michalski; Adam Raben; Shari Rudoler; Christopher U Jones; Howard Sandler
Journal:  Adv Radiat Oncol       Date:  2017-08-03
  8 in total

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