Literature DB >> 19361931

The high prevalence of substance use disorders among recent MDMA users compared with other drug users: Implications for intervention.

Li-Tzy Wu1, Andy C Parrott, Christopher L Ringwalt, Ashwin A Patkar, Paolo Mannelli, Dan G Blazer.   

Abstract

AIM: In light of the resurgence in MDMA use and its association with polysubstance use, we investigated the 12-month prevalence of substance use disorders (SUDs) among adult MDMA users to determine whether they are at risk of other drug-related problems that would call for targeted interventions.
METHODS: Data were drawn from the 2006 National Survey on Drug Use and Health. Past-year adult drug users were grouped into three mutually exclusive categories: 1) recent MDMA users, who had used the drug within the past year; 2) former MDMA users, who had a history of using this drug but had not done so within the past year; and 3) other drug users, who had never used MDMA. Logistic regression procedures were used to estimate the association between respondents' SUDs and MDMA use while adjusting for their socioeconomic status, mental health, age of first use, and history of polydrug use.
RESULTS: Approximately 14% of adults reported drug use in the past year, and 24% of those past-year drug users reported a history of MDMA use. Recent MDMA users exhibited the highest prevalence of disorders related to alcohol (41%), marijuana (30%), cocaine (10%), pain reliever/opioid (8%), and tranquilizer (3%) use. Adjusted logistic regression analyses revealed that, relative to other drug users, those who had recently used MDMA were twice as likely to meet criteria for marijuana and pain reliever/opioid use disorders. They were also about twice as likely as former MDMA users to meet criteria for marijuana, cocaine, and tranquilizer use disorders.
CONCLUSIONS: Seven out of ten recent MDMA users report experiencing an SUD in the past year. Adults who have recently used MDMA should be screened for possible SUDs to ensure early detection and treatment.

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Substances:

Year:  2009        PMID: 19361931      PMCID: PMC2745898          DOI: 10.1016/j.addbeh.2009.03.029

Source DB:  PubMed          Journal:  Addict Behav        ISSN: 0306-4603            Impact factor:   3.913


  42 in total

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Review 2.  MDMA ('ecstasy') and other 'club drugs'. The new epidemic.

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3.  Inhalant abuse and dependence among adolescents in the United States.

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4.  Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication.

Authors:  Ronald C Kessler; Wai Tat Chiu; Olga Demler; Kathleen R Merikangas; Ellen E Walters
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5.  Age of onset of drug use and its association with DSM-IV drug abuse and dependence: results from the National Longitudinal Alcohol Epidemiologic Survey.

Authors:  B F Grant; D A Dawson
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6.  Adolescent sexual behavior, drug use, and violence: increased reporting with computer survey technology.

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7.  Problematic versus non-problematic ecstasy/MDMA use: the influence of drug usage patterns and pre-existing psychiatric factors.

Authors:  K Soar; J J D Turner; A C Parrott
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8.  Understanding reasons for drug use amongst young people: a functional perspective.

Authors:  A Boys; J Marsden; J Strang
Journal:  Health Educ Res       Date:  2001-08

9.  Concurrent use of methamphetamine, MDMA, LSD, ketamine, GHB, and flunitrazepam among American youths.

Authors:  Li-Tzy Wu; William E Schlenger; Deborah M Galvin
Journal:  Drug Alcohol Depend       Date:  2006-02-17       Impact factor: 4.492

10.  The nicotine dependence syndrome scale: a multidimensional measure of nicotine dependence.

Authors:  Saul Shiffman; Andrew Waters; Mary Hickcox
Journal:  Nicotine Tob Res       Date:  2004-04       Impact factor: 4.244

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2.  The variety of ecstasy/MDMA users: results from the National Epidemiologic Survey on alcohol and related conditions.

Authors:  Li-Tzy Wu; Andy C Parrott; Christopher L Ringwalt; Chongming Yang; Dan G Blazer
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3.  Hallucinogen-related disorders in a national sample of adolescents: the influence of ecstasy/MDMA use.

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Review 4.  Club drugs: review of the 'rave' with a note of concern for the Indian scenario.

Authors:  Kaustav Chakraborty; Rajarshi Neogi; Debasish Basu
Journal:  Indian J Med Res       Date:  2011-06       Impact factor: 2.375

5.  Neural Mechanisms Underlying the Rewarding and Therapeutic Effects of Ketamine as a Treatment for Alcohol Use Disorder.

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Journal:  Front Behav Neurosci       Date:  2020-12-10       Impact factor: 3.558

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