Literature DB >> 19358908

Does statin usage reduce the risk of corticosteroid-related osteonecrosis in renal transplant population?

Muhammad Ajmal1, A J Matas, Michael Kuskowski, Edward Y Cheng.   

Abstract

The relationship between corticosteroids and osteonecrosis is well known. Limited data suggest that statins modulate cholesterol metabolism and may protect against osteonecrosis. The authors analyzed their prospective renal transplant database to determine if statin usage reduces the incidence of corticosteroid-related osteonecrosis and identified 2,881 renal transplantation patients who met the entry criteria. Among 338 patients on statins, 15 (4.4%) developed osteonecrosis, versus 180 of 2,543 (7%) patients who were not on statins. Osteonecrosis-free survival was similar in patients with and without statin exposure.

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Year:  2009        PMID： 19358908      PMCID： PMC2801433          DOI： 10.1016/j.ocl.2009.01.004

Source DB:  PubMed          Journal:  Orthop Clin North Am        ISSN： 0030-5898            Impact factor:   2.472


  30 in total

1.  Clinically occult avascular necrosis of the hip: prevalence in an asymptomatic population at risk.

Authors:  O Tervonen; D M Mueller; E L Matteson; J A Velosa; W W Ginsburg; R L Ehman
Journal:  Radiology       Date:  1992-03       Impact factor: 11.105

Review 2.  Nontraumatic avascular necrosis of the femoral head. Past, present, and future.

Authors:  J Arlet
Journal:  Clin Orthop Relat Res       Date:  1992-04       Impact factor: 4.176

Review 3.  Non-traumatic avascular necrosis of the femoral head.

Authors:  M A Mont; D S Hungerford
Journal:  J Bone Joint Surg Am       Date:  1995-03       Impact factor: 5.284

4.  Prevalence of previously undetected osteonecrosis of the femoral head in renal transplant recipients.

Authors:  B D Mulliken; D L Renfrew; R A Brand; C G Whitten
Journal:  Radiology       Date:  1994-09       Impact factor: 11.105

5.  Steroid-induced adipogenesis in a pluripotential cell line from bone marrow.

Authors:  Q Cui; G J Wang; G Balian
Journal:  J Bone Joint Surg Am       Date:  1997-07       Impact factor: 5.284

6.  Early arteriopathy and postulated pathogenesis of osteonecrosis of the femoral head. The intracapital arterioles.

Authors:  S Saito; K Ohzono; K Ono
Journal:  Clin Orthop Relat Res       Date:  1992-04       Impact factor: 4.176

7.  Early detection of avascular necrosis of the femoral head by MRI.

Authors:  M J Fordyce; L Solomon
Journal:  J Bone Joint Surg Br       Date:  1993-05

8.  Osteonecrosis of the hip in renal transplant recipients. Changes in functional status and magnetic resonance imaging findings over three years in three hundred five patients.

Authors:  J M Le Parc; T André; O Helenon; J Benoit; J B Paolaggi; H Kreis
Journal:  Rev Rhum Engl Ed       Date:  1996-06

9.  Risk factors for chronic rejection in renal allograft recipients.

Authors:  P S Almond; A Matas; K Gillingham; D L Dunn; W D Payne; P Gores; R Gruessner; J S Najarian
Journal:  Transplantation       Date:  1993-04       Impact factor: 4.939

10.  Fat embolism, intravascular coagulation, and osteonecrosis.

Authors:  J P Jones
Journal:  Clin Orthop Relat Res       Date:  1993-07       Impact factor: 4.176
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  28 in total

Review 1.  Musculoskeletal pain associated with corticosteroid therapy in cancer.

Authors:  Deborah A Frieze
Journal:  Curr Pain Headache Rep       Date:  2010-08

Review 2.  [Conservative treatment of atraumatic femoral head necrosis].

Authors:  U Maus; J Flechtenmacher; K M Peters
Journal:  Orthopade       Date:  2018-09       Impact factor: 1.087

3.  High risk of osteonecrosis of the femoral head in autoimmune disease patients showing no immediate increase in hepatic enzyme under steroid therapy.

Authors:  Shunichiro Okazaki; Satoshi Nagoya; Motohisa Yamamoto; Kenji Tateda; Hiroki Takahashi; Toshihiko Yamashita; Hiroshi Matsumoto
Journal:  Rheumatol Int       Date:  2012-01-04       Impact factor: 2.631

4.  National Cancer Institute, National Heart, Lung and Blood Institute/Pediatric Blood and Marrow Transplantation Consortium First International Consensus Conference on late effects after pediatric hematopoietic cell transplantation: the need for pediatric-specific long-term follow-up guidelines.

Authors:  Michael A Pulsipher; Roderick Skinner; George B McDonald; Sangeeta Hingorani; Saro H Armenian; Kenneth R Cooke; Clarisa Gracia; Anna Petryk; Smita Bhatia; Nancy Bunin; Michael L Nieder; Christopher C Dvorak; Lillian Sung; Jean E Sanders; Joanne Kurtzberg; K Scott Baker
Journal:  Biol Blood Marrow Transplant       Date:  2012-01-14       Impact factor: 5.742

5.  Real-time computerised tomography assisted porous tantalum implant in ARCO stage I-II non-traumatic osteonecrosis of the femoral head: minimum five-year follow up.

Authors:  Ruyin Hu; Pengfei Lei; Bo Li; Hao Liu; Xucheng Yang; Ting Wen; Yihe Hu; Xiaobin Tian
Journal:  Int Orthop       Date:  2018-03-27       Impact factor: 3.075

6.  ACTH protects against glucocorticoid-induced osteonecrosis of bone.

Authors:  Mone Zaidi; Li Sun; Lisa J Robinson; Irina L Tourkova; Li Liu; Yujuan Wang; Ling-Ling Zhu; Xuan Liu; Jianhua Li; Yuanzhen Peng; Guozhe Yang; Xingming Shi; Alice Levine; Jameel Iqbal; Beatrice B Yaroslavskiy; Carlos Isales; Harry C Blair
Journal:  Proc Natl Acad Sci U S A       Date:  2010-04-26       Impact factor: 11.205

Review 7.  Atraumatic Femoral Head Necrosis in Adults.

Authors:  Dariusch Arbab; Dietmar Pierre König
Journal:  Dtsch Arztebl Int       Date:  2016-01-22       Impact factor: 5.594

8.  Treatment with acetylsalicylic acid prevents short to mid-term radiographic progression of nontraumatic osteonecrosis of the femoral head: a pilot study.

Authors:  Anthony Albers; Alberto Carli; Bertrand Routy; Edward J Harvey; Chantal Séguin
Journal:  Can J Surg       Date:  2015-06       Impact factor: 2.089

Review 9.  Aseptic osteonecrosis of the hip in the adult: current evidence on conservative treatment.

Authors:  Raymond Klumpp; Carlo Trevisan
Journal:  Clin Cases Miner Bone Metab       Date:  2016-04-07

10.  Knee loading protects against osteonecrosis of the femoral head by enhancing vessel remodeling and bone healing.

Authors:  Daquan Liu; Xinle Li; Jie Li; Jing Yang; Hiroki Yokota; Ping Zhang
Journal:  Bone       Date:  2015-09-28       Impact factor: 4.398
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