PURPOSE: To determine the prevalence of osteonecrosis (ON) of the femoral head in renal transplant recipients and determine the natural history of previously undetected lesions. MATERIALS AND METHODS: The hips of 132 renal transplant recipients were examined with magnetic resonance (MR) imaging, with radiographs obtained only in the patients with positive MR images. RESULTS: Ten patients (15 hips) were considered to have ON (prevalence, 7.6%). Eleven of the hips had Ficat stage 0 disease (asymptomatic, preradiographic) and were followed up with serial radiography and MR imaging. Over an average follow-up of 22 months, only one of these lesions showed progression. The other 10 hips did not show progression at MR imaging or radiography. CONCLUSION: Previously undetected ON may have a benign course in many cases. Although a substantial number of patients have previously unsuspected disease, further study is necessary to assess the need for "prophylactic" surgery in such cases.
PURPOSE: To determine the prevalence of osteonecrosis (ON) of the femoral head in renal transplant recipients and determine the natural history of previously undetected lesions. MATERIALS AND METHODS: The hips of 132 renal transplant recipients were examined with magnetic resonance (MR) imaging, with radiographs obtained only in the patients with positive MR images. RESULTS: Ten patients (15 hips) were considered to have ON (prevalence, 7.6%). Eleven of the hips had Ficat stage 0 disease (asymptomatic, preradiographic) and were followed up with serial radiography and MR imaging. Over an average follow-up of 22 months, only one of these lesions showed progression. The other 10 hips did not show progression at MR imaging or radiography. CONCLUSION: Previously undetected ON may have a benign course in many cases. Although a substantial number of patients have previously unsuspected disease, further study is necessary to assess the need for "prophylactic" surgery in such cases.
Authors: Michael H M Chan; Paul K S Chan; James F Griffith; Iris H S Chan; Lydia C W Lit; C K Wong; Gregory E Antonio; Ester Y M Liu; David S C Hui; Michael W M Suen; Anil T Ahuja; Joseph J Y Sung; Christopher W K Lam Journal: Pathology Date: 2006-06 Impact factor: 5.306
Authors: Hui Lv; Sake J de Vlas; Wei Liu; Tian-Bao Wang; Zhao-Yang Cao; Chun-Peng Li; Wu-Chun Cao; Jan Hendrik Richardus Journal: Trop Med Int Health Date: 2009-06-05 Impact factor: 2.622