| Literature DB >> 19351115 |
Sarit S Agasti1, Apiwat Chompoosor, Chang-Cheng You, Partha Ghosh, Chae Kyu Kim, Vincent M Rotello.
Abstract
An anticancer drug (5-fluorouracil) was conjugated to the surface of gold nanoparticles through a photocleavable o-nitrobenzyl linkage. In this system, the particle serves as both cage and carrier for the therapeutic, providing a nontoxic conjugate that effectively releases the payload upon long wavelength UV irradiation.Entities:
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Year: 2009 PMID: 19351115 PMCID: PMC2673701 DOI: 10.1021/ja900591t
Source DB: PubMed Journal: J Am Chem Soc ISSN: 0002-7863 Impact factor: 15.419