| Literature DB >> 19133720 |
Chae Kyu Kim1, Partha Ghosh, Chiara Pagliuca, Zheng-Jiang Zhu, Stefano Menichetti, Vincent M Rotello.
Abstract
Gold nanoparticles functionalized with water-soluble zwitterionic ligands form kinetically stable complexes with hydrophobic drugs and dyes. These drugs and dyes are efficiently released into cells, as demonstrated through fluorescence microscopy and cytotoxicity assays. Significantly, there is little or no cellular uptake of particle, making these low toxicity particles promising for delivery applications.Entities:
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Year: 2009 PMID： 19133720 PMCID： PMC2645269 DOI： 10.1021/ja808137c
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419