| Literature DB >> 19348483 |
Enrique Lallana1, Eduardo Fernandez-Megia, Ricardo Riguera.
Abstract
The limitations (depolymerization and Cu contamination) in the use of Cu(I)-catalyzed azide-alkyne [3 + 2] cycloadditions (CuAAC) for the selective click functionalization of polysaccharide-based systems have been efficiently surpassed using a strain-promoted approach (SPAAC). The SPAAC decoration of chitosan-g-poly(ethylene glycol) nanostructures with an immunoglobulin G under physiological conditions represents a step forward in the preparation of immunonanoparticles.Entities:
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Year: 2009 PMID: 19348483 DOI: 10.1021/ja8100243
Source DB: PubMed Journal: J Am Chem Soc ISSN: 0002-7863 Impact factor: 15.419