Literature DB >> 19337742

[Cellular therapy in autoimmune disease].

K Thümmler1, A Ramming, H Schulze-Koops, A Skapenko.   

Abstract

In addition to natural thymus-derived regulatory T-cells (Tregs), peripherally-induced Tregs are of central importance in immune homeostasis. Homotypic interactions between activated effector T-cells and resting memory T-cells induced the generation of IL-10 and IFNgamma producing Tregs in vitro. This mechanism in Treg development allows new insights into T-cell vaccination, which has been employed in pilot trials of multiple sclerosis and rheumatoid arthritis with promising results.

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Mesh：

Year:  2009        PMID： 19337742     DOI： 10.1007/s00393-009-0458-y

Source DB:  PubMed          Journal:  Z Rheumatol        ISSN： 0340-1855            Impact factor:   1.372


  11 in total

Review 1.  Tregs in T cell vaccination: exploring the regulation of regulation.

Authors:  Irun R Cohen; Francisco J Quintana; Avishai Mimran
Journal:  J Clin Invest       Date:  2004-11       Impact factor: 14.808

2.  T-T cell interactions are mediated by adhesion molecules.

Authors:  S A Brod; M Purvee; D Benjamin; D A Hafler
Journal:  Eur J Immunol       Date:  1990-10       Impact factor: 5.532

3.  A synaptic basis for paracrine interleukin-2 signaling during homotypic T cell interaction.

Authors:  Catherine A Sabatos; Junsang Doh; Sumone Chakravarti; Rachel S Friedman; Priya G Pandurangi; Aaron J Tooley; Matthew F Krummel
Journal:  Immunity       Date:  2008-07-31       Impact factor: 31.745

Review 4.  Regulatory T cells and immune tolerance.

Authors:  Shimon Sakaguchi; Tomoyuki Yamaguchi; Takashi Nomura; Masahiro Ono
Journal:  Cell       Date:  2008-05-30       Impact factor: 41.582

5.  T cell vaccination in multiple sclerosis: results of a preliminary study.

Authors:  Jingwu Z Zhang; Victor M Rivera; Maria V Tejada-Simon; Deye Yang; Jian Hong; Sufanfg Li; Hani Haykal; James Killian; Ying C Q Zang
Journal:  J Neurol       Date:  2002-02       Impact factor: 4.849

6.  T cell vaccination in systemic lupus erythematosus with autologous activated T cells.

Authors:  Z G Li; R Mu; Z P Dai; X M Gao
Journal:  Lupus       Date:  2005       Impact factor: 2.911

7.  Vaccination with selected synovial T cells in rheumatoid arthritis.

Authors:  Guangjie Chen; Ningli Li; Ying C Q Zang; Dongqing Zhang; Dongyi He; Guozhang Feng; Liqing Ni; Rong Xu; Li Wang; Baihua Shen; Jingwu Z Zhang
Journal:  Arthritis Rheum       Date:  2007-02

8.  CD4+ regulatory T cell responses induced by T cell vaccination in patients with multiple sclerosis.

Authors:  Jian Hong; Ying C Q Zang; Hong Nie; Jingwu Z Zhang
Journal:  Proc Natl Acad Sci U S A       Date:  2006-03-17       Impact factor: 11.205

Review 9.  T-cell vaccination in multiple sclerosis.

Authors:  Anat Achiron; Mathilda Mandel
Journal:  Autoimmun Rev       Date:  2004-01       Impact factor: 9.754

10.  Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice.

Authors:  Kristin V Tarbell; Lucine Petit; Xiaopan Zuo; Priscilla Toy; Xunrong Luo; Amina Mqadmi; Hua Yang; Manikkam Suthanthiran; Svetlana Mojsov; Ralph M Steinman
Journal:  J Exp Med       Date:  2007-01-08       Impact factor: 14.307
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  1 in total

1.  Successful use of mRNA-nucleofection for overexpression of interleukin-10 in murine monocytes/macrophages for anti-inflammatory therapy in a murine model of autoimmune myocarditis.

Authors:  Oliver Zimmermann; Jörg M Homann; Anna Bangert; Anna-Maria Müller; Georgi Hristov; Stefan Goeser; Juliane M Wiehe; Stefan Zittrich; Wolfgang Rottbauer; Jan Torzewski; Gabriele Pfitzer; Hugo A Katus; Ziya Kaya
Journal:  J Am Heart Assoc       Date:  2012-12-19       Impact factor: 5.501
  1 in total

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