Literature DB >> 19321137

Binding reactions: epigenetic switches, signal transduction and cancer.

Mark Ptashne1.   

Abstract

Simple binding interactions lie at the heart of disparate biological functions. Multiple negative and positive 'add-ons', often with small individual effects, make elementary systems that work, work better. Cancer illustrates various of these fundamental processes gone awry.

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Year:  2009        PMID: 19321137     DOI: 10.1016/j.cub.2009.02.015

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  23 in total

1.  Probability landscape of heritable and robust epigenetic state of lysogeny in phage lambda.

Authors:  Youfang Cao; Hsiao-Mei Lu; Jie Liang
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-11       Impact factor: 11.205

2.  Linking cell signaling and the epigenetic machinery.

Authors:  Helai P Mohammad; Stephen B Baylin
Journal:  Nat Biotechnol       Date:  2010-10       Impact factor: 54.908

Review 3.  The chemistry of regulation of genes and other things.

Authors:  Mark Ptashne
Journal:  J Biol Chem       Date:  2014-01-02       Impact factor: 5.157

4.  An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation.

Authors:  Dimitrios Iliopoulos; Heather A Hirsch; Kevin Struhl
Journal:  Cell       Date:  2009-10-29       Impact factor: 41.582

5.  Principles of a switch.

Authors:  Mark Ptashne
Journal:  Nat Chem Biol       Date:  2011-07-18       Impact factor: 15.040

6.  Quantitation of protein-protein interactions by thermal stability shift analysis.

Authors:  Curtis J Layton; Homme W Hellinga
Journal:  Protein Sci       Date:  2011-07-11       Impact factor: 6.725

7.  A RSC/nucleosome complex determines chromatin architecture and facilitates activator binding.

Authors:  Monique Floer; Xin Wang; Vidya Prabhu; Georgina Berrozpe; Santosh Narayan; Dan Spagna; David Alvarez; Jude Kendall; Alexander Krasnitz; Asya Stepansky; James Hicks; Gene O Bryant; Mark Ptashne
Journal:  Cell       Date:  2010-04-30       Impact factor: 41.582

Review 8.  Regulation of histone methylation by noncoding RNAs.

Authors:  Richard I Joh; Christina M Palmieri; Ian T Hill; Mo Motamedi
Journal:  Biochim Biophys Acta       Date:  2014-06-17

9.  DNA demethylation dynamics.

Authors:  Nidhi Bhutani; David M Burns; Helen M Blau
Journal:  Cell       Date:  2011-09-16       Impact factor: 41.582

10.  An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis.

Authors:  Maria Hatziapostolou; Christos Polytarchou; Eleni Aggelidou; Alexandra Drakaki; George A Poultsides; Savina A Jaeger; Hisanobu Ogata; Michael Karin; Kevin Struhl; Margarita Hadzopoulou-Cladaras; Dimitrios Iliopoulos
Journal:  Cell       Date:  2011-12-09       Impact factor: 41.582

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