Literature DB >> 19303311

Optimized therapeutic neutron beam for accelerator-based BNCT by analyzing the neutron angular distribution from (7)Li(p,n)(7)Be reaction.

Kyung-O Kim1, Jong Kyung Kim, Soon Young Kim.   

Abstract

Perpendicular neutrons (i.e., solid angle bin of 50-150 degrees ) among ones generated from (7)Li(p,n)(7)Be reaction were used to produce an optimized therapeutic neutron beam for accelerator-based BNCT. A new beam port assembly was also designed to shape the fast neutrons into epithermal ones and to reduce unnecessary radiation including gammas. As a result of a simulation, it is found that a tumor at a depth of 60mm from the head skin could be treated within 5 minutes, if a typical tumor is assumed to be taken about 20RBEGy for therapeutic treatment. It is, thus, expected that the neutrons emitted into the solid angle bin of 50-150 degrees from (7)Li(p,n)(7)Be reaction are very effective in producing epithermal neutron beams for BNCT.

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Year:  2009        PMID: 19303311     DOI: 10.1016/j.apradiso.2009.02.004

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  4 in total

Review 1.  KSNM60 in Non-thyroidal Radionuclide Therapy: Leaping into the Future.

Authors:  Byung Hyun Byun; Myoung Hyoun Kim; Yeon-Hee Han; Hwan-Jeong Jeong
Journal:  Nucl Med Mol Imaging       Date:  2021-08-23

2.  Therapeutic potential of atmospheric neutrons.

Authors:  Cyril Voyant; Rudy Roustit; Jennifer Tatje; Katia Biffi; Delphine Leschi; Jérome Briançon; Céline Lantieri Marcovici
Journal:  Rep Pract Oncol Radiother       Date:  2010-12-04

3.  Design of Beam Shaping Assemblies for Accelerator-Based BNCT With Multi-Terminals.

Authors:  Guangru Li; Wei Jiang; Lu Zhang; Weiqiang Chen; Qiang Li
Journal:  Front Public Health       Date:  2021-03-11

4.  Optimized beam shaping assembly for a 2.1-MeV proton-accelerator-based neutron source for boron neutron capture therapy.

Authors:  Pablo Torres-Sánchez; Ignacio Porras; Nataliya Ramos-Chernenko; Fernando Arias de Saavedra; Javier Praena
Journal:  Sci Rep       Date:  2021-04-07       Impact factor: 4.379

  4 in total

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