Literature DB >> 33777888

Design of Beam Shaping Assemblies for Accelerator-Based BNCT With Multi-Terminals.

Guangru Li1,2,3,4, Wei Jiang1, Lu Zhang1, Weiqiang Chen1,2,3,4, Qiang Li1,2,3,4.   

Abstract

To moderate fast neutrons produced by accelerator to appropriate therapeutic energies for boron neutron capture therapy (BNCT), beam shaping assembly (BSA) is required definitely. In this work, based on a model of 2.5 MeV/30 mA proton accelerator, the Monte Carlo simulation software MCNPX was employed to design multi-terminal BSAs. All parameters for both the thermal and epithermal neutron beams at the exit ports of the designed BSAs meet the treatment recommendation values proposed by the International Atomic Energy Agency (IAEA). The clinical parameters of the thermal and epithermal neutron beams were also calculated for clinical indication consideration.
Copyright © 2021 Li, Jiang, Zhang, Chen and Li.

Entities:  

Keywords:  accelerator-based BNCT; beam shaping assembly; epithermal neutron; multi-terminal; thermal neutron

Year:  2021        PMID: 33777888      PMCID: PMC7991290          DOI: 10.3389/fpubh.2021.642561

Source DB:  PubMed          Journal:  Front Public Health        ISSN: 2296-2565


  9 in total

1.  The study of physics and thermal characteristics for in-hospital neutron irradiator (IHNI).

Authors:  Guotu Ke; Ziyong Sun; Feng Shen; Tiancai Liu; Yiguo Li; Yongmao Zhou
Journal:  Appl Radiat Isot       Date:  2009-04-09       Impact factor: 1.513

2.  Optimized therapeutic neutron beam for accelerator-based BNCT by analyzing the neutron angular distribution from (7)Li(p,n)(7)Be reaction.

Authors:  Kyung-O Kim; Jong Kyung Kim; Soon Young Kim
Journal:  Appl Radiat Isot       Date:  2009-02-14       Impact factor: 1.513

3.  The uses of nuclear disintegration in the diagnosis and treatment of brain tumor.

Authors:  W H SWEET
Journal:  N Engl J Med       Date:  1951-12-06       Impact factor: 91.245

4.  Towards the final BSA modeling for the accelerator-driven BNCT facility at INFN LNL.

Authors:  C Ceballos; J Esposito; S Agosteo; P Colautti; V Conte; D Moro; A Pola
Journal:  Appl Radiat Isot       Date:  2011-02-01       Impact factor: 1.513

5.  Experimental verification of beam characteristics for cyclotron-based epithermal neutron source (C-BENS).

Authors:  H Tanaka; Y Sakurai; M Suzuki; S Masunaga; T Mitsumoto; K Fujita; G Kashino; Y Kinashi; Y Liu; M Takada; K Ono; A Maruhashi
Journal:  Appl Radiat Isot       Date:  2011-03-21       Impact factor: 1.513

Review 6.  Physics of epi-thermal boron neutron capture therapy (epi-thermal BNCT).

Authors:  Ryoichi Seki; Yushi Wakisaka; Nami Morimoto; Masaaki Takashina; Masahiko Koizumi; Hiroshi Toki; Mitsuhiro Fukuda
Journal:  Radiol Phys Technol       Date:  2017-11-20

7.  Clinical results of long-surviving brain tumor patients who underwent boron neutron capture therapy.

Authors:  H Hatanaka; Y Nakagawa
Journal:  Int J Radiat Oncol Biol Phys       Date:  1994-03-30       Impact factor: 7.038

Review 8.  Boron neutron capture therapy of primary and metastatic brain tumors.

Authors:  R F Barth; A H Soloway
Journal:  Mol Chem Neuropathol       Date:  1994 Feb-Apr

9.  Beam shaping assembly design of 7Li(p,n)7Be neutron source for boron neutron capture therapy of deep-seated tumor.

Authors:  L Zaidi; M Belgaid; S Taskaev; R Khelifi
Journal:  Appl Radiat Isot       Date:  2018-05-31       Impact factor: 1.513

  9 in total

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