Amanda L Jones1, John K Snyder. 1. Center for Chemical Methodology and Library Development, and the Department of Chemistry, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, USA.
Abstract
The Rh(I)-catalyzed inter- and intramolecular [2+2+2] cyclization of diynes with alpha,beta-unsaturated enones proceeds with microwave promotion in good yields. This chemistry was applied to the synthesis of (-)-alcyopterosin I.
The Rh(I)-catalyzed iical">nter- aical">nd iical">ntramolecular [2+2+2] cyclizatioical">n of n class="Chemical">diynes with alpha,beta-unsaturated enones proceeds with microwave promotion in good yields. This chemistry was applied to the synthesis of (-)-alcyopterosin I.