Literature DB >> 20210307

Synthesis of unique scaffolds via Diels-Alder cycloadditions of tetrasubstituted cyclohexadienes.

Amanda L Jones1, John K Snyder.   

Abstract

Diels-Alder cycloadditions of highly substituted cyclohexadienes derived from rhodium-mediated [2 + 2 + 2] cyclizations are reported. Reactive heterodienophiles, including singlet oxygen ((1)O(2)), 4-substituted-1,2,4-triazoline-3,5-diones (TADs), and aryl- and acylnitroso compounds were employed, yielding novel heterocyclic products.

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Year:  2010        PMID： 20210307      PMCID： PMC2851182          DOI： 10.1021/ol100318f

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  16 in total

1.  Alkali metals plus silica gel: powerful reducing agents and convenient hydrogen sources.

Authors:  James L Dye; Kevin D Cram; Stephanie A Urbin; Mikhail Y Redko; James E Jackson; Michael Lefenfeld
Journal:  J Am Chem Soc       Date:  2005-07-06       Impact factor: 15.419

2.  Copper-catalyzed Diels-Alder reactions.

Authors:  Sébastien Reymond; Janine Cossy
Journal:  Chem Rev       Date:  2008-12       Impact factor: 60.622

3.  Synthesis of highly substituted cyclohexenes via mixed Lewis acid-catalyzed Diels-Alder reactions of highly substituted dienes and dienophiles.

Authors:  Michael E Jung; David Ho; Hiufung V Chu
Journal:  Org Lett       Date:  2005-04-14       Impact factor: 6.005

4.  Novel [2+2+2]annulation of 1,6-diynes mediated by methallylchromate or methallylmagnesium chloride under CrCl3 catalysis.

Authors:  T Nishikawa; H Kakiya; H Shinokubo; K Oshima
Journal:  J Am Chem Soc       Date:  2001-05-16       Impact factor: 15.419

5.  Intramolecular rhodium-catalyzed [2+2+2] cyclizations of diynes with enones.

Authors:  Amanda L Jones; John K Snyder
Journal:  J Org Chem       Date:  2009-04-03       Impact factor: 4.354

6.  A new pd-catalyzed cascade reaction for the synthesis of strained aromatic polycycles.

Authors:  Gaëlle Blond; Christophe Bour; Bahaâ Salem; Jean Suffert
Journal:  Org Lett       Date:  2008-02-15       Impact factor: 6.005

7.  Cytotoxicity of artemisinin-related endoperoxides to Ehrlich ascites tumor cells.

Authors:  H J Woerdenbag; T A Moskal; N Pras; T M Malingré; F S el-Feraly; H H Kampinga; A W Konings
Journal:  J Nat Prod       Date:  1993-06       Impact factor: 4.050

8.  Preparation and biological evaluation of novel leucomycin analogs derived from nitroso Diels-Alder reactions.

Authors:  Baiyuan Yang; Tina Zöllner; Peter Gebhardt; Ute Möllmann; Marvin J Miller
Journal:  Org Biomol Chem       Date:  2009-12-11       Impact factor: 3.876

9.  Coupling of the R-Cp or indenyl ligand with the diene moiety of bis(substituted cyclopentadienyl)- or bis(indenyl)zirconacyclopentadienes.

Authors:  Shenyong Ren; Eri Igarashi; Kiyohiko Nakajima; Ken-ichiro Kanno; Tamotsu Takahashi
Journal:  J Am Chem Soc       Date:  2009-06-10       Impact factor: 15.419

10.  Syntheses and biological activity studies of novel sterol analogs from nitroso Diels-Alder reactions of ergosterol.

Authors:  Baiyuan Yang; Patricia A Miller; Ute Möllmann; Marvin J Miller
Journal:  Org Lett       Date:  2009-07-02       Impact factor: 6.005
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  3 in total

1.  Synthesis and chemical diversity analysis of bicyclo[3.3.1]non-3-en-2-ones.

Authors:  Jared T Hammill; Julia Contreras-García; Aaron M Virshup; David Beratan; Weitao Yang; Peter Wipf
Journal:  Tetrahedron       Date:  2010-03-31       Impact factor: 2.457

2.  Remodelling of the natural product fumagillol employing a reaction discovery approach.

Authors:  Bradley R Balthaser; Meghan C Maloney; Aaron B Beeler; John A Porco; John K Snyder
Journal:  Nat Chem       Date:  2011-12       Impact factor: 24.427

Review 3.  Stereo- and regioselectivity of the hetero-Diels-Alder reaction of nitroso derivatives with conjugated dienes.

Authors:  Lucie Brulíková; Aidan Harrison; Marvin J Miller; Jan Hlaváč
Journal:  Beilstein J Org Chem       Date:  2016-09-01       Impact factor: 2.883
  3 in total

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