Literature DB >> 19268515

Nanomedicine: perspective and promises with ligand-directed molecular imaging.

Dipanjan Pan1, Gregory M Lanza, Samuel A Wickline, Shelton D Caruthers.   

Abstract

Molecular imaging and targeted drug delivery play an important role toward personalized medicine, which is the future of patient management. Of late, nanoparticle-based molecular imaging has emerged as an interdisciplinary area, which shows promises to understand the components, processes, dynamics and therapies of a disease at a molecular level. The unprecedented potential of nanoplatforms for early detection, diagnosis and personalized treatment of diseases, have found application in every biomedical imaging modality. Biological and biophysical barriers are overcome by the integration of targeting ligands, imaging agents and therapeutics into the nanoplatform which allow for theranostic applications. In this article, we have discussed the opportunities and potential of targeted molecular imaging with various modalities putting a particular emphasis on perfluorocarbon nanoemulsion-based platform technology.

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Year:  2009        PMID: 19268515     DOI: 10.1016/j.ejrad.2009.01.042

Source DB:  PubMed          Journal:  Eur J Radiol        ISSN: 0720-048X            Impact factor:   3.528


  27 in total

1.  Ultrasound-mediated tumor imaging and nanotherapy using drug loaded, block copolymer stabilized perfluorocarbon nanoemulsions.

Authors:  Natalya Rapoport; Kweon-Ho Nam; Roohi Gupta; Zhongao Gao; Praveena Mohan; Allison Payne; Nick Todd; Xin Liu; Taeho Kim; Jill Shea; Courtney Scaife; Dennis L Parker; Eun-Kee Jeong; Anne M Kennedy
Journal:  J Control Release       Date:  2011-01-26       Impact factor: 9.776

2.  Manganese-based MRI contrast agents: past, present and future.

Authors:  Dipanjan Pan; Anne H Schmieder; Samuel A Wickline; Gregory M Lanza
Journal:  Tetrahedron       Date:  2011-11-04       Impact factor: 2.457

Review 3.  Revisiting an old friend: manganese-based MRI contrast agents.

Authors:  Dipanjan Pan; Shelton D Caruthers; Angana Senpan; Ann H Schmieder; Samuel A Wickline; Gregory M Lanza
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2010-09-21

4.  In Vivo Micro-CT Imaging of Human Mesenchymal Stem Cells Labeled with Gold-Poly-L-Lysine Nanocomplexes.

Authors:  Taeho Kim; Nohyun Lee; Dian R Arifin; Irina Shats; Miroslaw Janowski; Piotr Walczak; Taeghwan Hyeon; Jeff W M Bulte
Journal:  Adv Funct Mater       Date:  2016-11-28       Impact factor: 18.808

Review 5.  Phase-shift, stimuli-responsive perfluorocarbon nanodroplets for drug delivery to cancer.

Authors:  Natalya Rapoport
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2012-06-22

Review 6.  Phase-shift, stimuli-responsive drug carriers for targeted delivery.

Authors:  Brian E O'Neill; Natalya Rapoport
Journal:  Ther Deliv       Date:  2011-09

7.  Interaction of melittin peptides with perfluorocarbon nanoemulsion particles.

Authors:  Sun-Joo Lee; Paul H Schlesinger; Samuel A Wickline; Gregory M Lanza; Nathan A Baker
Journal:  J Phys Chem B       Date:  2011-12-06       Impact factor: 2.991

8.  A facile synthesis of novel self-assembled gold nanorods designed for near-infrared imaging.

Authors:  Dipanjan Pan; Manojit Pramanik; Angana Senpan; Samuel A Wickline; Lihong V Wang; Gregory M Lanza
Journal:  J Nanosci Nanotechnol       Date:  2010-12

9.  Multifunctional nanoemulsion platform for imaging guided therapy evaluated in experimental cancer.

Authors:  Anita Gianella; Peter A Jarzyna; Venkatesh Mani; Sarayu Ramachandran; Claudia Calcagno; Jun Tang; Benjamin Kann; Wouter J R Dijk; Victor L Thijssen; Arjan W Griffioen; Gert Storm; Zahi A Fayad; Willem J M Mulder
Journal:  ACS Nano       Date:  2011-05-25       Impact factor: 15.881

10.  Tunable plasmonic nanobubbles for cell theranostics.

Authors:  E Y Lukianova-Hleb; E Y Hanna; J H Hafner; D O Lapotko
Journal:  Nanotechnology       Date:  2010-01-25       Impact factor: 3.874

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