Literature DB >> 19264051

A prediction model for determining over ground walking speed after locomotor training in persons with motor incomplete spinal cord injury.

Patricia Winchester1, Patricia Smith, Nathan Foreman, James M Mosby, Fides Pacheco, Ross Querry, Keith Tansey.   

Abstract

BACKGROUND/
OBJECTIVE: To develop and test a clinically relevant model for predicting the recovery of over ground walking speed after 36 sessions of progressive body weight-supported treadmill training (BWSTT) in individuals with motor incomplete spinal cord injury (SCI).
DESIGN: A retrospective review and stepwise regression analysis of a SCI clinical outcomes data set.
SETTING: Outpatient SCI laboratory.
SUBJECTS: Thirty individuals with a motor incomplete SCI who had participated in locomotor training with BWSTT. Eight individuals with similar diagnoses were used to prospectively test the prediction model. MAIN OUTCOME MEASURES: Over ground walking speed was assessed using the 10-m walking test.
METHODS: The locomotor training program consisted of 36 sessions of sequential comprehensive training comprised of robotic assisted BWSTT, followed by manual assisted BWSTT, and over ground walking. The dose of locomotor training was standardized throughout the protocol.
RESULTS: Clinical characteristics with predictive value for walking speed were time from injury onset, the presence or absence of voluntary bowel and bladder voiding, a functional spasticity assessment, and over ground walking speed before locomotor training. The model identified that these characteristics accounted for 78.3% of the variability in the actual final over ground walking speed after 36 sessions of locomotor training. The model was successful in prospectively predicting over ground walking speed in the 8 test participants within 4.15 +/- 2.22 cm/s in their recovered walking speed.
CONCLUSIONS: This prediction model can identify individuals who are most likely to experience success using locomotor training by determining an expected magnitude of training effect, thereby allowing individualized decisions regarding the use of this intensive approach to rehabilitation.

Entities:  

Mesh:

Year:  2009        PMID: 19264051      PMCID: PMC2647503          DOI: 10.1080/10790268.2009.11760754

Source DB:  PubMed          Journal:  J Spinal Cord Med        ISSN: 1079-0268            Impact factor:   1.985


  30 in total

1.  Effect of locomotor training related to clinical and electrophysiological examinations in spinal cord injured humans.

Authors:  G Colombo; M Wirz; V Dietz
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2.  Spinal cord injury: prognostic indicators.

Authors:  Y Folman; W el Masri
Journal:  Injury       Date:  1989-03       Impact factor: 2.586

3.  Assessment of lower urinary tract functional deficit in rats with contusive spinal cord injury.

Authors:  V Pikov; R A Gillis; L Jasmin; J R Wrathall
Journal:  J Neurotrauma       Date:  1998-05       Impact factor: 5.269

4.  Effectiveness of automated locomotor training in patients with chronic incomplete spinal cord injury: a multicenter trial.

Authors:  Markus Wirz; David H Zemon; Ruediger Rupp; Anke Scheel; Gery Colombo; Volker Dietz; T George Hornby
Journal:  Arch Phys Med Rehabil       Date:  2005-04       Impact factor: 3.966

5.  Targeting recovery: priorities of the spinal cord-injured population.

Authors:  Kim D Anderson
Journal:  J Neurotrauma       Date:  2004-10       Impact factor: 5.269

6.  Robotic-assisted, body-weight-supported treadmill training in individuals following motor incomplete spinal cord injury.

Authors:  T George Hornby; David H Zemon; Donielle Campbell
Journal:  Phys Ther       Date:  2005-01

7.  A physiologically based clinical measure for spastic reflexes in spinal cord injury.

Authors:  Ela N Benz; T George Hornby; Rita K Bode; Robert A Scheidt; Brian D Schmit
Journal:  Arch Phys Med Rehabil       Date:  2005-01       Impact factor: 3.966

8.  Prediction of ambulatory performance based on motor scores derived from standards of the American Spinal Injury Association.

Authors:  R L Waters; R Adkins; J Yakura; D Vigil
Journal:  Arch Phys Med Rehabil       Date:  1994-07       Impact factor: 3.966

9.  Spinal cord injury: prognosis for ambulation based on sensory examination in patients who are initially motor complete.

Authors:  K S Crozier; V Graziani; J F Ditunno; G J Herbison
Journal:  Arch Phys Med Rehabil       Date:  1991-02       Impact factor: 3.966

10.  Laufband therapy based on 'rules of spinal locomotion' is effective in spinal cord injured persons.

Authors:  A Wernig; S Müller; A Nanassy; E Cagol
Journal:  Eur J Neurosci       Date:  1995-04-01       Impact factor: 3.386

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  12 in total

1.  Interventions to Reduce Spasticity and Improve Function in People With Chronic Incomplete Spinal Cord Injury: Distinctions Revealed by Different Analytical Methods.

Authors:  Lynsey D Duffell; Geoffrey L Brown; Mehdi M Mirbagheri
Journal:  Neurorehabil Neural Repair       Date:  2014-11-14       Impact factor: 3.919

Review 2.  A systematic review of the effects of pharmacological agents on walking function in people with spinal cord injury.

Authors:  Antoinette Domingo; Abdulaziz A Al-Yahya; Yousif Asiri; Janice J Eng; Tania Lam
Journal:  J Neurotrauma       Date:  2012-02-29       Impact factor: 5.269

3.  Volitional muscle strength in the legs predicts changes in walking speed following locomotor training in people with chronic spinal cord injury.

Authors:  Jaynie F Yang; Jonathan Norton; Jennifer Nevett-Duchcherer; Francois D Roy; Douglas P Gross; Monica A Gorassini
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4.  A combination therapy of neural and glial restricted precursor cells and chronic quipazine treatment paired with passive cycling promotes quipazine-induced stepping in adult spinalized rats.

Authors:  Elizabeth A Dugan; Jed S Shumsky
Journal:  J Spinal Cord Med       Date:  2014-10-20       Impact factor: 1.985

Review 5.  Training to achieve over ground walking after spinal cord injury: a review of who, what, when, and how.

Authors:  Jaynie F Yang; Kristin E Musselman
Journal:  J Spinal Cord Med       Date:  2012-09       Impact factor: 1.985

6.  Activity-based Therapies in Spinal Cord Injury:: Clinical Focus and Empirical Evidence in Three Independent Programs.

Authors:  Michael L Jones; Eric Harness; Paula Denison; Candy Tefertiller; Nicholas Evans; Cathy A Larson
Journal:  Top Spinal Cord Inj Rehabil       Date:  2012

7.  Leg strength, preferred walking speed, and daily step activity in adults with incomplete spinal cord injuries.

Authors:  Sandra L Stevens; Dana K Fuller; Don W Morgan
Journal:  Top Spinal Cord Inj Rehabil       Date:  2013

Review 8.  Supraspinal Control Predicts Locomotor Function and Forecasts Responsiveness to Training after Spinal Cord Injury.

Authors:  Edelle C Field-Fote; Jaynie F Yang; D Michele Basso; Monica A Gorassini
Journal:  J Neurotrauma       Date:  2016-12-20       Impact factor: 5.269

9.  Effects of serotonergic medications on locomotor performance in humans with incomplete spinal cord injury.

Authors:  Kristan A Leech; Catherine R Kinnaird; T George Hornby
Journal:  J Neurotrauma       Date:  2014-06-20       Impact factor: 5.269

10.  Walking improvement in chronic incomplete spinal cord injury with exoskeleton robotic training (WISE): a randomized controlled trial.

Authors:  Dylan J Edwards; Gail Forrest; Mar Cortes; Margaret M Weightman; Cristina Sadowsky; Shuo-Hsiu Chang; Kimberly Furman; Amy Bialek; Sara Prokup; John Carlow; Leslie VanHiel; Laura Kemp; Darrell Musick; Marc Campo; Arun Jayaraman
Journal:  Spinal Cord       Date:  2022-01-29       Impact factor: 2.473

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